Gadoteridol for mr imaging of lymphatic vessels in lymphoedematous patients : initial experience after intracutaneous injection
Identifieur interne : 007916 ( Main/Merge ); précédent : 007915; suivant : 007917Gadoteridol for mr imaging of lymphatic vessels in lymphoedematous patients : initial experience after intracutaneous injection
Auteurs : C. Lohrmann [Allemagne] ; E. Foeldi [Allemagne] ; J.-P. Bartholomae [Allemagne] ; M. Langer [Allemagne]Source :
- British journal of radiology [ 0007-1285 ] ; 2007.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme, Médecine nucléaire.
English descriptors
- KwdEn :
Abstract
The aim of this study was to evaluate the feasibility of gadoteridol in visualizing lymphatic vessels of lymphoedematous patients after intracutaneous injection. 20 lower extremities in 10 lymphoedematous patients were examined. Gadoteridol (9 ml) was subdivided into five portions and injected intracutaneously into the dorsal aspect of each foot. For MRI, a three-dimensional spoiled gradient echo sequence was performed. No complications were observed during or after intracutaneous injection of gadoteridol. The lymphoedema was bilateral in seven and unilateral in three of the examined patients. Contrast enhancement of gadoteridol was detected in lymphatic vessels at the level of the lower leg in 17 lower extremities (85%). Enhancing lymphatic vessels of the upper leg were observed in 11 lower extremities (55%). Furthermore, gadoteridol enhanced 10 out of 20 inguinal lymph node groups (50%). No external iliac lymph nodes were observed in any of the patients. Regions of dermal backflow, indicating proximal lymphatic obstruction, were seen in 13 lower extremities (65%). As soon as 15 min after gadoteridol injection, accompanying venous enhancement was detected in all lower extremities (100%). MRI of lymphatic vessels in lymphoedematous patients is safe and feasible after intracutaneous injection of gadoteridol if the diagnosis of lymphoedema necessitates a better definition for optimal therapeutic planning or an objective, diagnostic baseline is required. The proposed technique represents a minimally invasive imaging method of identifying anatomical and physiological derangements in lymphatic vessels.
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 000440
- to stream PascalFrancis, to step Curation: 000520
- to stream PascalFrancis, to step Checkpoint: 000472
Links to Exploration step
Pascal:07-0433599Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Gadoteridol for mr imaging of lymphatic vessels in lymphoedematous patients : initial experience after intracutaneous injection</title><author><name sortKey="Lohrmann, C" sort="Lohrmann, C" uniqKey="Lohrmann C" first="C." last="Lohrmann">C. Lohrmann</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Division of Diagnostic Radiology, Department of Radiology, University Hospital of Freiburg, Hugstetter Strasse 55</s1><s2>79106, Freiburg</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Fribourg-en-Brisgau</region><settlement type="city">Fribourg-en-Brisgau</settlement></placeName></affiliation></author><author><name sortKey="Foeldi, E" sort="Foeldi, E" uniqKey="Foeldi E" first="E." last="Foeldi">E. Foeldi</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Foeldi Clinic for Lymphology, Hinterzarten, Rölehofweg 2-6</s1> <s2>79856, Hinterzarten</s2><s3>DEU</s3><sZ>2 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Hinterzarten</wicri:noRegion><wicri:noRegion>Rölehofweg 2-6</wicri:noRegion> <wicri:noRegion>79856, Hinterzarten</wicri:noRegion></affiliation></author><author><name sortKey="Bartholomae, J P" sort="Bartholomae, J P" uniqKey="Bartholomae J" first="J.-P." last="Bartholomae">J.-P. Bartholomae</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Division of Diagnostic Radiology, Department of Radiology, University Hospital of Freiburg, Hugstetter Strasse 55</s1><s2>79106, Freiburg</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Fribourg-en-Brisgau</region><settlement type="city">Fribourg-en-Brisgau</settlement></placeName></affiliation></author><author><name sortKey="Langer, M" sort="Langer, M" uniqKey="Langer M" first="M." last="Langer">M. Langer</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Division of Diagnostic Radiology, Department of Radiology, University Hospital of Freiburg, Hugstetter Strasse 55</s1><s2>79106, Freiburg</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Fribourg-en-Brisgau</region><settlement type="city">Fribourg-en-Brisgau</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">07-0433599</idno><date when="2007">2007</date><idno type="stanalyst">PASCAL 07-0433599 INIST</idno><idno type="RBID">Pascal:07-0433599</idno><idno type="wicri:Area/PascalFrancis/Corpus">000440</idno><idno type="wicri:Area/PascalFrancis/Curation">000520</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000472</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000472</idno><idno type="wicri:doubleKey">0007-1285:2007:Lohrmann C:gadoteridol:for:mr</idno><idno type="wicri:Area/Main/Merge">007916</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Gadoteridol for mr imaging of lymphatic vessels in lymphoedematous patients : initial experience after intracutaneous injection</title><author><name sortKey="Lohrmann, C" sort="Lohrmann, C" uniqKey="Lohrmann C" first="C." last="Lohrmann">C. Lohrmann</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Division of Diagnostic Radiology, Department of Radiology, University Hospital of Freiburg, Hugstetter Strasse 55</s1><s2>79106, Freiburg</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Fribourg-en-Brisgau</region><settlement type="city">Fribourg-en-Brisgau</settlement></placeName></affiliation></author><author><name sortKey="Foeldi, E" sort="Foeldi, E" uniqKey="Foeldi E" first="E." last="Foeldi">E. Foeldi</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Foeldi Clinic for Lymphology, Hinterzarten, Rölehofweg 2-6</s1> <s2>79856, Hinterzarten</s2><s3>DEU</s3><sZ>2 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Hinterzarten</wicri:noRegion><wicri:noRegion>Rölehofweg 2-6</wicri:noRegion> <wicri:noRegion>79856, Hinterzarten</wicri:noRegion></affiliation></author><author><name sortKey="Bartholomae, J P" sort="Bartholomae, J P" uniqKey="Bartholomae J" first="J.-P." last="Bartholomae">J.-P. Bartholomae</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Division of Diagnostic Radiology, Department of Radiology, University Hospital of Freiburg, Hugstetter Strasse 55</s1><s2>79106, Freiburg</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Fribourg-en-Brisgau</region><settlement type="city">Fribourg-en-Brisgau</settlement></placeName></affiliation></author><author><name sortKey="Langer, M" sort="Langer, M" uniqKey="Langer M" first="M." last="Langer">M. Langer</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Division of Diagnostic Radiology, Department of Radiology, University Hospital of Freiburg, Hugstetter Strasse 55</s1><s2>79106, Freiburg</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Fribourg-en-Brisgau</region><settlement type="city">Fribourg-en-Brisgau</settlement></placeName></affiliation></author></analytic><series><title level="j" type="main">British journal of radiology</title><title level="j" type="abbreviated">Br. j. radiol.</title><idno type="ISSN">0007-1285</idno><imprint><date when="2007">2007</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">British journal of radiology</title><title level="j" type="abbreviated">Br. j. radiol.</title><idno type="ISSN">0007-1285</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Blood vessel</term><term>Contrast media</term><term>Derm</term><term>Diagnosis</term><term>Foot</term><term>Gadoteridol</term><term>Human</term><term>Inguinal</term><term>Intravenous administration</term><term>Leg</term><term>Lymph node</term><term>Lymphatic</term><term>Lymphatic system</term><term>Lymphedema</term><term>Nuclear magnetic resonance imaging</term><term>Nuclear medicine</term><term>Paramagnetic contrast agent</term><term>Radiology</term><term>Treatment</term><term>Vein</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Lymphoedème</term><term>Gadotéridol</term><term>Imagerie RMN</term><term>Lymphatique</term><term>Système lymphatique</term><term>Ganglion lymphatique</term><term>Homme</term><term>Vaisseau sanguin</term><term>Pied</term><term>Jambe</term><term>Inguinal</term><term>Derme</term><term>Voie intraveineuse</term><term>Veine</term><term>Diagnostic</term><term>Traitement</term><term>Médecine nucléaire</term><term>Radiologie</term><term>Agent contraste paramagnétique</term><term>Produit contraste</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term><term>Médecine nucléaire</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The aim of this study was to evaluate the feasibility of gadoteridol in visualizing lymphatic vessels of lymphoedematous patients after intracutaneous injection. 20 lower extremities in 10 lymphoedematous patients were examined. Gadoteridol (9 ml) was subdivided into five portions and injected intracutaneously into the dorsal aspect of each foot. For MRI, a three-dimensional spoiled gradient echo sequence was performed. No complications were observed during or after intracutaneous injection of gadoteridol. The lymphoedema was bilateral in seven and unilateral in three of the examined patients. Contrast enhancement of gadoteridol was detected in lymphatic vessels at the level of the lower leg in 17 lower extremities (85%). Enhancing lymphatic vessels of the upper leg were observed in 11 lower extremities (55%). Furthermore, gadoteridol enhanced 10 out of 20 inguinal lymph node groups (50%). No external iliac lymph nodes were observed in any of the patients. Regions of dermal backflow, indicating proximal lymphatic obstruction, were seen in 13 lower extremities (65%). As soon as 15 min after gadoteridol injection, accompanying venous enhancement was detected in all lower extremities (100%). MRI of lymphatic vessels in lymphoedematous patients is safe and feasible after intracutaneous injection of gadoteridol if the diagnosis of lymphoedema necessitates a better definition for optimal therapeutic planning or an objective, diagnostic baseline is required. The proposed technique represents a minimally invasive imaging method of identifying anatomical and physiological derangements in lymphatic vessels.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>Bade-Wurtemberg</li><li>District de Fribourg-en-Brisgau</li></region><settlement><li>Fribourg-en-Brisgau</li></settlement></list><tree><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Lohrmann, C" sort="Lohrmann, C" uniqKey="Lohrmann C" first="C." last="Lohrmann">C. Lohrmann</name></region><name sortKey="Bartholomae, J P" sort="Bartholomae, J P" uniqKey="Bartholomae J" first="J.-P." last="Bartholomae">J.-P. Bartholomae</name><name sortKey="Foeldi, E" sort="Foeldi, E" uniqKey="Foeldi E" first="E." last="Foeldi">E. Foeldi</name><name sortKey="Langer, M" sort="Langer, M" uniqKey="Langer M" first="M." last="Langer">M. Langer</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 007916 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 007916 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Merge
|type= RBID
|clé= Pascal:07-0433599
|texte= Gadoteridol for mr imaging of lymphatic vessels in lymphoedematous patients : initial experience after intracutaneous injection
}}
| This area was generated with Dilib version V0.6.31. |  |