High-Grade Breast Epithelioid Angiosarcoma Secondary to Radiotherapy Metastasizing to the Contralateral Lymph Node: Unusual Presentation and Potential Pitfall
Identifieur interne : 004E80 ( Main/Merge ); précédent : 004E79; suivant : 004E81High-Grade Breast Epithelioid Angiosarcoma Secondary to Radiotherapy Metastasizing to the Contralateral Lymph Node: Unusual Presentation and Potential Pitfall
Auteurs : Ana Luísa Cunha ; Isabel AmendoeiraSource :
- Breast Care [ 1661-3791 ] ; 2011.
Abstract
Breast angiosarcoma is a rare disease occurring as primary tumour or secondary to lymphoedema or radiotherapy. The more frequent use of breast-conserving therapy and radiotherapy for breast carcinoma explains the increasing diagnosis of these tumours.
We report a case of a breast epithelioid angiosarcoma which metastasized to the contralateral axillary lymph node, occurring 4 years after breast-conserving therapy with axillary lymph node dissection and radiotherapy. The patient presented skin lesions and an axillary lump (clinically diagnosed as carcinoma relapse and lymph node metastasis). Fine-needle cytology on both lesions and a core needle biopsy of the axillary lump were carried out. Differential diagnosis included carcinoma, malignant melanoma, and angiosarcoma. Immunohistochemistry confirmed the diagnosis of angiosarcoma.
Breast angiosarcoma is a challenge – clinically, radiologically and pathologically – and requires a high index of suspicion in susceptible patients.
Url:
DOI: 10.1159/000329323
PubMed: 21779229
PubMed Central: 3132971
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