Selective Inguinal Lymphadenectomy in the Treatment of Invasive Squamous Cell Carcinoma of the Vulva
Identifieur interne : 004B85 ( Main/Merge ); précédent : 004B84; suivant : 004B86Selective Inguinal Lymphadenectomy in the Treatment of Invasive Squamous Cell Carcinoma of the Vulva
Auteurs : Christopher P. Desimone [États-Unis] ; Jeffrey Elder [États-Unis] ; John R. Van Nagell [États-Unis]Source :
- International Journal of Surgical Oncology [ 2090-1402 ] ; 2011.
Abstract
En bloc radical vulvectomy with bilateral inguinofemoral lymphadenectomy has now been replaced by radical wide excision and selective inguinal lymphadenectomy based on the stage and location of invasive vulvar cancer. Early stage lateral cancers can be effectively treated by radical wide excision and ipsilateral superficial inguinal lymphadenectomy. Lymph node mapping using perilesional injection of radiocolloid and blue dye may identify sentinel lymph nodes which can be removed, thereby avoiding the morbidity of full inguinal lymphadenectomy in selected patients with early stage disease.
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DOI: 10.1155/2011/284374
PubMed: 22312500
PubMed Central: 3263651
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Desimone</name><affiliation wicri:level="1"><nlm:aff id="I1">Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The University of Kentucky Chandler Medical Center-Markey Cancer Center, 800 Rose Street, Lexington, KY 40536-0293, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The University of Kentucky Chandler Medical Center-Markey Cancer Center, 800 Rose Street, Lexington, KY 40536-0293</wicri:regionArea><wicri:noRegion>KY 40536-0293</wicri:noRegion></affiliation></author><author><name sortKey="Elder, Jeffrey" sort="Elder, Jeffrey" uniqKey="Elder J" first="Jeffrey" last="Elder">Jeffrey Elder</name><affiliation wicri:level="1"><nlm:aff id="I1">Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The University of Kentucky Chandler Medical Center-Markey Cancer Center, 800 Rose Street, Lexington, KY 40536-0293, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The University of Kentucky Chandler Medical Center-Markey Cancer Center, 800 Rose Street, Lexington, KY 40536-0293</wicri:regionArea><wicri:noRegion>KY 40536-0293</wicri:noRegion></affiliation></author><author><name sortKey="Van Nagell, John R" sort="Van Nagell, John R" uniqKey="Van Nagell J" first="John R." last="Van Nagell">John R. Van Nagell</name><affiliation wicri:level="1"><nlm:aff id="I1">Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The University of Kentucky Chandler Medical Center-Markey Cancer Center, 800 Rose Street, Lexington, KY 40536-0293, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The University of Kentucky Chandler Medical Center-Markey Cancer Center, 800 Rose Street, Lexington, KY 40536-0293</wicri:regionArea><wicri:noRegion>KY 40536-0293</wicri:noRegion></affiliation></author></analytic><series><title level="j">International Journal of Surgical Oncology</title><idno type="ISSN">2090-1402</idno><idno type="eISSN">2090-1410</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>En bloc radical vulvectomy with bilateral inguinofemoral lymphadenectomy has now been replaced by radical wide excision and selective inguinal lymphadenectomy based on the stage and location of invasive vulvar cancer. Early stage lateral cancers can be effectively treated by radical wide excision and ipsilateral superficial inguinal lymphadenectomy. Lymph node mapping using perilesional injection of radiocolloid and blue dye may identify sentinel lymph nodes which can be removed, thereby avoiding the morbidity of full inguinal lymphadenectomy in selected patients with early stage disease.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Jemal, A" uniqKey="Jemal A">A Jemal</name></author><author><name sortKey="Siegel, R" uniqKey="Siegel R">R Siegel</name></author><author><name sortKey="Ward, E" uniqKey="Ward E">E Ward</name></author><author><name sortKey="Hao, Y" uniqKey="Hao Y">Y Hao</name></author><author><name sortKey="Xu, J" uniqKey="Xu J">J Xu</name></author><author><name sortKey="Thun, Mj" uniqKey="Thun M">MJ Thun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Plentl, Aa" uniqKey="Plentl A">AA Plentl</name></author><author><name sortKey="Friedman, Ea" uniqKey="Friedman E">EA 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