The effects of low-thrombin fibrin sealant on wound serous drainage, seroma formation and length of postoperative stay in patients undergoing axillary node dissection for breast cancer. A randomized controlled trial.
Identifieur interne : 002428 ( Main/Merge ); précédent : 002427; suivant : 002429The effects of low-thrombin fibrin sealant on wound serous drainage, seroma formation and length of postoperative stay in patients undergoing axillary node dissection for breast cancer. A randomized controlled trial.
Auteurs : Raffaella Benevento [Italie] ; Antonio Santoriello ; Gianluca Pellino ; Guido Sciaudone ; Giuseppe Candilio ; G Serena De Fatico ; Francesco Selvaggi ; Silvestro CanonicoSource :
- International journal of surgery (London, England) [ 1743-9159 ] ; 2014.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Aisselle, Aspiration (technique), Carcinome canalaire du sein (), Carcinome canalaire du sein (anatomopathologie), Carcinome lobulaire (), Carcinome lobulaire (anatomopathologie), Colle de fibrine (usage thérapeutique), Durée du séjour, Femelle, Humains, Hémostatiques (usage thérapeutique), Incidence, Lymphadénectomie (effets indésirables), Lymphoedème (), Lymphoedème (épidémiologie), Mastectomie (effets indésirables), Méthode en double aveugle, Sujet âgé, Sérome (), Sérome (épidémiologie), Thrombine (usage thérapeutique), Tumeurs du sein (), Tumeurs du sein (anatomopathologie).
- MESH :
- anatomopathologie : Carcinome canalaire du sein, Carcinome lobulaire, Tumeurs du sein.
- effets indésirables : Lymphadénectomie, Mastectomie.
- usage thérapeutique : Colle de fibrine, Hémostatiques, Thrombine.
- épidémiologie : Lymphoedème, Sérome.
- Adulte, Adulte d'âge moyen, Aisselle, Aspiration (technique), Carcinome canalaire du sein, Carcinome lobulaire, Durée du séjour, Femelle, Humains, Incidence, Lymphoedème, Méthode en double aveugle, Sujet âgé, Sérome, Tumeurs du sein.
English descriptors
- KwdEn :
- Adult, Aged, Axilla, Breast Neoplasms (pathology), Breast Neoplasms (surgery), Carcinoma, Ductal, Breast (pathology), Carcinoma, Ductal, Breast (surgery), Carcinoma, Lobular (pathology), Carcinoma, Lobular (surgery), Double-Blind Method, Female, Fibrin Tissue Adhesive (therapeutic use), Hemostatics (therapeutic use), Humans, Incidence, Length of Stay, Lymph Node Excision (adverse effects), Lymphedema (epidemiology), Lymphedema (prevention & control), Mastectomy (adverse effects), Middle Aged, Seroma (epidemiology), Seroma (prevention & control), Suction, Thrombin (therapeutic use).
- MESH :
- chemical , therapeutic use : Fibrin Tissue Adhesive, Hemostatics, Thrombin.
- adverse effects : Lymph Node Excision, Mastectomy.
- epidemiology : Lymphedema, Seroma.
- pathology : Breast Neoplasms, Carcinoma, Ductal, Breast, Carcinoma, Lobular.
- prevention & control : Lymphedema, Seroma.
- surgery : Breast Neoplasms, Carcinoma, Ductal, Breast, Carcinoma, Lobular.
- Adult, Aged, Axilla, Double-Blind Method, Female, Humans, Incidence, Length of Stay, Middle Aged, Suction.
Abstract
Breast cancer surgery with axillary lymphadenectomy may be associated with prolonged stay of the drain in the axilla due to high wound output, which may require further treatments and prolong the length of stay, impairing quality of life. No definitive data are available concerning how to prevent this complication. Our aim was to assess the efficacy of a new low-thrombin fibrin glue in reducing the serous output from the axillary surgical wound in patients undergoing axillary node dissection for breast cancer, and its long-term effects on lymphedema.
DOI: 10.1016/j.ijsu.2014.10.005
PubMed: 25462702
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pubmed:25462702Le document en format XML
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<wicri:regionArea>Unit of General and Geriatric Surgery, Department of Medical, Surgical, Neurological, Metabolic and Ageing Sciences, Second University of Naples, Piazza Miraglia 5, 80138 Naples</wicri:regionArea>
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<author><name sortKey="Santoriello, Antonio" sort="Santoriello, Antonio" uniqKey="Santoriello A" first="Antonio" last="Santoriello">Antonio Santoriello</name>
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<author><name sortKey="Sciaudone, Guido" sort="Sciaudone, Guido" uniqKey="Sciaudone G" first="Guido" last="Sciaudone">Guido Sciaudone</name>
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<author><name sortKey="Candilio, Giuseppe" sort="Candilio, Giuseppe" uniqKey="Candilio G" first="Giuseppe" last="Candilio">Giuseppe Candilio</name>
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<author><name sortKey="De Fatico, G Serena" sort="De Fatico, G Serena" uniqKey="De Fatico G" first="G Serena" last="De Fatico">G Serena De Fatico</name>
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<author><name sortKey="Selvaggi, Francesco" sort="Selvaggi, Francesco" uniqKey="Selvaggi F" first="Francesco" last="Selvaggi">Francesco Selvaggi</name>
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<author><name sortKey="Canonico, Silvestro" sort="Canonico, Silvestro" uniqKey="Canonico S" first="Silvestro" last="Canonico">Silvestro Canonico</name>
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<series><title level="j">International journal of surgery (London, England)</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Axilla</term>
<term>Breast Neoplasms (pathology)</term>
<term>Breast Neoplasms (surgery)</term>
<term>Carcinoma, Ductal, Breast (pathology)</term>
<term>Carcinoma, Ductal, Breast (surgery)</term>
<term>Carcinoma, Lobular (pathology)</term>
<term>Carcinoma, Lobular (surgery)</term>
<term>Double-Blind Method</term>
<term>Female</term>
<term>Fibrin Tissue Adhesive (therapeutic use)</term>
<term>Hemostatics (therapeutic use)</term>
<term>Humans</term>
<term>Incidence</term>
<term>Length of Stay</term>
<term>Lymph Node Excision (adverse effects)</term>
<term>Lymphedema (epidemiology)</term>
<term>Lymphedema (prevention & control)</term>
<term>Mastectomy (adverse effects)</term>
<term>Middle Aged</term>
<term>Seroma (epidemiology)</term>
<term>Seroma (prevention & control)</term>
<term>Suction</term>
<term>Thrombin (therapeutic use)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Aisselle</term>
<term>Aspiration (technique)</term>
<term>Carcinome canalaire du sein ()</term>
<term>Carcinome canalaire du sein (anatomopathologie)</term>
<term>Carcinome lobulaire ()</term>
<term>Carcinome lobulaire (anatomopathologie)</term>
<term>Colle de fibrine (usage thérapeutique)</term>
<term>Durée du séjour</term>
<term>Femelle</term>
<term>Humains</term>
<term>Hémostatiques (usage thérapeutique)</term>
<term>Incidence</term>
<term>Lymphadénectomie (effets indésirables)</term>
<term>Lymphoedème ()</term>
<term>Lymphoedème (épidémiologie)</term>
<term>Mastectomie (effets indésirables)</term>
<term>Méthode en double aveugle</term>
<term>Sujet âgé</term>
<term>Sérome ()</term>
<term>Sérome (épidémiologie)</term>
<term>Thrombine (usage thérapeutique)</term>
<term>Tumeurs du sein ()</term>
<term>Tumeurs du sein (anatomopathologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Fibrin Tissue Adhesive</term>
<term>Hemostatics</term>
<term>Thrombin</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Lymph Node Excision</term>
<term>Mastectomy</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Carcinome canalaire du sein</term>
<term>Carcinome lobulaire</term>
<term>Tumeurs du sein</term>
</keywords>
<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Lymphadénectomie</term>
<term>Mastectomie</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Lymphedema</term>
<term>Seroma</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Breast Neoplasms</term>
<term>Carcinoma, Ductal, Breast</term>
<term>Carcinoma, Lobular</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Lymphedema</term>
<term>Seroma</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Breast Neoplasms</term>
<term>Carcinoma, Ductal, Breast</term>
<term>Carcinoma, Lobular</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Colle de fibrine</term>
<term>Hémostatiques</term>
<term>Thrombine</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Lymphoedème</term>
<term>Sérome</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Axilla</term>
<term>Double-Blind Method</term>
<term>Female</term>
<term>Humans</term>
<term>Incidence</term>
<term>Length of Stay</term>
<term>Middle Aged</term>
<term>Suction</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Aisselle</term>
<term>Aspiration (technique)</term>
<term>Carcinome canalaire du sein</term>
<term>Carcinome lobulaire</term>
<term>Durée du séjour</term>
<term>Femelle</term>
<term>Humains</term>
<term>Incidence</term>
<term>Lymphoedème</term>
<term>Méthode en double aveugle</term>
<term>Sujet âgé</term>
<term>Sérome</term>
<term>Tumeurs du sein</term>
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<front><div type="abstract" xml:lang="en">Breast cancer surgery with axillary lymphadenectomy may be associated with prolonged stay of the drain in the axilla due to high wound output, which may require further treatments and prolong the length of stay, impairing quality of life. No definitive data are available concerning how to prevent this complication. Our aim was to assess the efficacy of a new low-thrombin fibrin glue in reducing the serous output from the axillary surgical wound in patients undergoing axillary node dissection for breast cancer, and its long-term effects on lymphedema.</div>
</front>
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