Locoregional treatment of early breast cancer with isolated tumor cells or micrometastases on sentinel lymph node biopsy
Identifieur interne : 000E98 ( Main/Merge ); précédent : 000E97; suivant : 000E99Locoregional treatment of early breast cancer with isolated tumor cells or micrometastases on sentinel lymph node biopsy
Auteurs : Agnès Tallet ; Eric Lambaudie ; Monique Cohen ; Mathieu Minsat ; Marie Bannier ; Michel Resbeut ; Gilles HouvenaeghelSource :
- World Journal of Clinical Oncology [ 2218-4333 ] ; 2016.
Abstract
The advent of sentinel lymph-node technique has led to a shift in lymph-node staging, due to the emergence of new entities namely micrometastases (pN1mi) and isolated tumor cells [pN0(i+)]. The prognostic significance of this low positivity in axillary lymph nodes is currently debated, as is, therefore its management. This article provides updates evidence-based medicine data to take into account for treatment decision-making in this setting, discussing the locoregional treatment in pN0(i+) and pN1mi patients (completion axillary dissection, axillary irradiation with or without regional nodes irradiation, or observation), according to systemic treatment, with the goal to help physicians in their daily practice.
Url:
DOI: 10.5306/wjco.v7.i2.243
PubMed: 27081647
PubMed Central: 4826970
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PMC:4826970Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>The advent of sentinel lymph-node technique has led to a shift in lymph-node staging, due to the emergence of new entities namely micrometastases (pN1mi) and isolated tumor cells [pN0(i+)]. The prognostic significance of this low positivity in axillary lymph nodes is currently debated, as is, therefore its management. This article provides updates evidence-based medicine data to take into account for treatment decision-making in this setting, discussing the locoregional treatment in pN0(i+) and pN1mi patients (completion axillary dissection, axillary irradiation with or without regional nodes irradiation, or observation), according to systemic treatment, with the goal to help physicians in their daily practice.</p>
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