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Locoregional treatment of early breast cancer with isolated tumor cells or micrometastases on sentinel lymph node biopsy

Identifieur interne : 000E98 ( Main/Merge ); précédent : 000E97; suivant : 000E99

Locoregional treatment of early breast cancer with isolated tumor cells or micrometastases on sentinel lymph node biopsy

Auteurs : Agnès Tallet ; Eric Lambaudie ; Monique Cohen ; Mathieu Minsat ; Marie Bannier ; Michel Resbeut ; Gilles Houvenaeghel

Source :

RBID : PMC:4826970

Abstract

The advent of sentinel lymph-node technique has led to a shift in lymph-node staging, due to the emergence of new entities namely micrometastases (pN1mi) and isolated tumor cells [pN0(i+)]. The prognostic significance of this low positivity in axillary lymph nodes is currently debated, as is, therefore its management. This article provides updates evidence-based medicine data to take into account for treatment decision-making in this setting, discussing the locoregional treatment in pN0(i+) and pN1mi patients (completion axillary dissection, axillary irradiation with or without regional nodes irradiation, or observation), according to systemic treatment, with the goal to help physicians in their daily practice.


Url:
DOI: 10.5306/wjco.v7.i2.243
PubMed: 27081647
PubMed Central: 4826970

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PMC:4826970

Le document en format XML

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<name sortKey="Minsat, Mathieu" sort="Minsat, Mathieu" uniqKey="Minsat M" first="Mathieu" last="Minsat">Mathieu Minsat</name>
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<name sortKey="Bannier, Marie" sort="Bannier, Marie" uniqKey="Bannier M" first="Marie" last="Bannier">Marie Bannier</name>
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<name sortKey="Resbeut, Michel" sort="Resbeut, Michel" uniqKey="Resbeut M" first="Michel" last="Resbeut">Michel Resbeut</name>
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<p>The advent of sentinel lymph-node technique has led to a shift in lymph-node staging, due to the emergence of new entities namely micrometastases (pN1mi) and isolated tumor cells [pN0(i+)]. The prognostic significance of this low positivity in axillary lymph nodes is currently debated, as is, therefore its management. This article provides updates evidence-based medicine data to take into account for treatment decision-making in this setting, discussing the locoregional treatment in pN0(i+) and pN1mi patients (completion axillary dissection, axillary irradiation with or without regional nodes irradiation, or observation), according to systemic treatment, with the goal to help physicians in their daily practice.</p>
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