The passive biomechanics of human pelvic collecting lymphatic vessels
Identifieur interne : 000090 ( Main/Merge ); précédent : 000089; suivant : 000091The passive biomechanics of human pelvic collecting lymphatic vessels
Auteurs : Dimitrios Athanasiou [Royaume-Uni] ; Lowell T. Edgar [Royaume-Uni] ; Mohammad Jafarnejad [Royaume-Uni] ; Katherine Nixon [Royaume-Uni] ; Delfim Duarte [Royaume-Uni] ; Edwin D. Hawkins [Australie] ; Samira Jamalian [Royaume-Uni] ; Paula Cunnea [Royaume-Uni] ; Cristina Lo Celso [Royaume-Uni] ; Shunichi Kobayashi [Japon] ; Christina Fotopoulou [Royaume-Uni] ; James E. Moore [Royaume-Uni]Source :
- PLoS ONE [ 1932-6203 ] ; 2017.
Abstract
The lymphatic system has a major significance in the metastatic pathways in women’s cancers. Lymphatic pumping depends on both extrinsic and intrinsic mechanisms, and the mechanical behavior of lymphatic vessels regulates the function of the system. However, data on the mechanical properties and function of human lymphatics are lacking. Our aim is to characterize, for the first time, the passive biomechanical behavior of human collecting lymphatic vessels removed at pelvic lymph node dissection during primary debulking surgeries for epithelial ovarian cancer. Isolated vessels were cannulated and then pressurized at varying levels of applied axial stretch in a calcium-free Krebs buffer. Pressurized vessels were then imaged using multi-photon microscopy for collagen-elastin structural composition and fiber orientation. Both pressure-diameter and force-elongation responses were highly nonlinear, and axial stretching of the vessel served to decrease diameter at constant pressure. Pressure-diameter behavior for the human vessels is very similar to data from rat mesenteric vessels, though the human vessels were approximately 10× larger than those from rats. Multiphoton microscopy revealed the vessels to be composed of an inner layer of elastin with an outer layer of aligned collagen fibers. This is the first study that successfully described the passive biomechanical response and composition of human lymphatic vessels in patients with ovarian cancer. Future work should expand on this knowledge base with investigations of vessels from other anatomical locations, contractile behavior, and the implications on metastatic cell transport.
Url:
DOI: 10.1371/journal.pone.0183222
PubMed: 28827843
PubMed Central: 5565099
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 004431
- to stream Pmc, to step Curation: 004430
- to stream Pmc, to step Checkpoint: 000030
- to stream Ncbi, to step Merge: 009402
- to stream Ncbi, to step Curation: 009402
- to stream Ncbi, to step Checkpoint: 009402
Links to Exploration step
PMC:5565099Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The passive biomechanics of human pelvic collecting lymphatic vessels</title>
<author><name sortKey="Athanasiou, Dimitrios" sort="Athanasiou, Dimitrios" uniqKey="Athanasiou D" first="Dimitrios" last="Athanasiou">Dimitrios Athanasiou</name>
<affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Bioengineering, Imperial College, London, South Kensington Campus, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Bioengineering, Imperial College, London, South Kensington Campus, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Edgar, Lowell T" sort="Edgar, Lowell T" uniqKey="Edgar L" first="Lowell T." last="Edgar">Lowell T. Edgar</name>
<affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Bioengineering, Imperial College, London, South Kensington Campus, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Bioengineering, Imperial College, London, South Kensington Campus, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jafarnejad, Mohammad" sort="Jafarnejad, Mohammad" uniqKey="Jafarnejad M" first="Mohammad" last="Jafarnejad">Mohammad Jafarnejad</name>
<affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Bioengineering, Imperial College, London, South Kensington Campus, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Bioengineering, Imperial College, London, South Kensington Campus, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Nixon, Katherine" sort="Nixon, Katherine" uniqKey="Nixon K" first="Katherine" last="Nixon">Katherine Nixon</name>
<affiliation wicri:level="3"><nlm:aff id="aff002"><addr-line>Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, Hammersmith Hospital, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, Hammersmith Hospital, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Duarte, Delfim" sort="Duarte, Delfim" uniqKey="Duarte D" first="Delfim" last="Duarte">Delfim Duarte</name>
<affiliation wicri:level="3"><nlm:aff id="aff003"><addr-line>Department of Life Sciences and the Francis Crick Institute, Imperial College London, South Kensington Campus, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Life Sciences and the Francis Crick Institute, Imperial College London, South Kensington Campus, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hawkins, Edwin D" sort="Hawkins, Edwin D" uniqKey="Hawkins E" first="Edwin D." last="Hawkins">Edwin D. Hawkins</name>
<affiliation wicri:level="1"><nlm:aff id="aff004"><addr-line>Immunology Division at the Walter and Eliza Hall, Institute of Medical Research, Department of Medical Biology, University of Melbourne, Victoria, Australia</addr-line>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Immunology Division at the Walter and Eliza Hall, Institute of Medical Research, Department of Medical Biology, University of Melbourne, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jamalian, Samira" sort="Jamalian, Samira" uniqKey="Jamalian S" first="Samira" last="Jamalian">Samira Jamalian</name>
<affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Bioengineering, Imperial College, London, South Kensington Campus, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Bioengineering, Imperial College, London, South Kensington Campus, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Cunnea, Paula" sort="Cunnea, Paula" uniqKey="Cunnea P" first="Paula" last="Cunnea">Paula Cunnea</name>
<affiliation wicri:level="3"><nlm:aff id="aff002"><addr-line>Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, Hammersmith Hospital, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, Hammersmith Hospital, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lo Celso, Cristina" sort="Lo Celso, Cristina" uniqKey="Lo Celso C" first="Cristina" last="Lo Celso">Cristina Lo Celso</name>
<affiliation wicri:level="3"><nlm:aff id="aff003"><addr-line>Department of Life Sciences and the Francis Crick Institute, Imperial College London, South Kensington Campus, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Life Sciences and the Francis Crick Institute, Imperial College London, South Kensington Campus, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kobayashi, Shunichi" sort="Kobayashi, Shunichi" uniqKey="Kobayashi S" first="Shunichi" last="Kobayashi">Shunichi Kobayashi</name>
<affiliation wicri:level="1"><nlm:aff id="aff005"><addr-line>Department of Mechanical Engineering and Robotics, Shinshu University, Ueda, Nagano, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Mechanical Engineering and Robotics, Shinshu University, Ueda, Nagano</wicri:regionArea>
<wicri:noRegion>Nagano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Fotopoulou, Christina" sort="Fotopoulou, Christina" uniqKey="Fotopoulou C" first="Christina" last="Fotopoulou">Christina Fotopoulou</name>
<affiliation wicri:level="3"><nlm:aff id="aff002"><addr-line>Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, Hammersmith Hospital, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, Hammersmith Hospital, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Moore, James E" sort="Moore, James E" uniqKey="Moore J" first="James E." last="Moore">James E. Moore</name>
<affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Bioengineering, Imperial College, London, South Kensington Campus, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Bioengineering, Imperial College, London, South Kensington Campus, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">28827843</idno>
<idno type="pmc">5565099</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565099</idno>
<idno type="RBID">PMC:5565099</idno>
<idno type="doi">10.1371/journal.pone.0183222</idno>
<date when="2017">2017</date>
<idno type="wicri:Area/Pmc/Corpus">004431</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">004431</idno>
<idno type="wicri:Area/Pmc/Curation">004430</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">004430</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000030</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000030</idno>
<idno type="wicri:Area/Ncbi/Merge">009402</idno>
<idno type="wicri:Area/Ncbi/Curation">009402</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">009402</idno>
<idno type="wicri:Area/Main/Merge">000090</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The passive biomechanics of human pelvic collecting lymphatic vessels</title>
<author><name sortKey="Athanasiou, Dimitrios" sort="Athanasiou, Dimitrios" uniqKey="Athanasiou D" first="Dimitrios" last="Athanasiou">Dimitrios Athanasiou</name>
<affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Bioengineering, Imperial College, London, South Kensington Campus, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Bioengineering, Imperial College, London, South Kensington Campus, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Edgar, Lowell T" sort="Edgar, Lowell T" uniqKey="Edgar L" first="Lowell T." last="Edgar">Lowell T. Edgar</name>
<affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Bioengineering, Imperial College, London, South Kensington Campus, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Bioengineering, Imperial College, London, South Kensington Campus, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jafarnejad, Mohammad" sort="Jafarnejad, Mohammad" uniqKey="Jafarnejad M" first="Mohammad" last="Jafarnejad">Mohammad Jafarnejad</name>
<affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Bioengineering, Imperial College, London, South Kensington Campus, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Bioengineering, Imperial College, London, South Kensington Campus, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Nixon, Katherine" sort="Nixon, Katherine" uniqKey="Nixon K" first="Katherine" last="Nixon">Katherine Nixon</name>
<affiliation wicri:level="3"><nlm:aff id="aff002"><addr-line>Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, Hammersmith Hospital, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, Hammersmith Hospital, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Duarte, Delfim" sort="Duarte, Delfim" uniqKey="Duarte D" first="Delfim" last="Duarte">Delfim Duarte</name>
<affiliation wicri:level="3"><nlm:aff id="aff003"><addr-line>Department of Life Sciences and the Francis Crick Institute, Imperial College London, South Kensington Campus, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Life Sciences and the Francis Crick Institute, Imperial College London, South Kensington Campus, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hawkins, Edwin D" sort="Hawkins, Edwin D" uniqKey="Hawkins E" first="Edwin D." last="Hawkins">Edwin D. Hawkins</name>
<affiliation wicri:level="1"><nlm:aff id="aff004"><addr-line>Immunology Division at the Walter and Eliza Hall, Institute of Medical Research, Department of Medical Biology, University of Melbourne, Victoria, Australia</addr-line>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Immunology Division at the Walter and Eliza Hall, Institute of Medical Research, Department of Medical Biology, University of Melbourne, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jamalian, Samira" sort="Jamalian, Samira" uniqKey="Jamalian S" first="Samira" last="Jamalian">Samira Jamalian</name>
<affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Bioengineering, Imperial College, London, South Kensington Campus, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Bioengineering, Imperial College, London, South Kensington Campus, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Cunnea, Paula" sort="Cunnea, Paula" uniqKey="Cunnea P" first="Paula" last="Cunnea">Paula Cunnea</name>
<affiliation wicri:level="3"><nlm:aff id="aff002"><addr-line>Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, Hammersmith Hospital, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, Hammersmith Hospital, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lo Celso, Cristina" sort="Lo Celso, Cristina" uniqKey="Lo Celso C" first="Cristina" last="Lo Celso">Cristina Lo Celso</name>
<affiliation wicri:level="3"><nlm:aff id="aff003"><addr-line>Department of Life Sciences and the Francis Crick Institute, Imperial College London, South Kensington Campus, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Life Sciences and the Francis Crick Institute, Imperial College London, South Kensington Campus, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kobayashi, Shunichi" sort="Kobayashi, Shunichi" uniqKey="Kobayashi S" first="Shunichi" last="Kobayashi">Shunichi Kobayashi</name>
<affiliation wicri:level="1"><nlm:aff id="aff005"><addr-line>Department of Mechanical Engineering and Robotics, Shinshu University, Ueda, Nagano, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Mechanical Engineering and Robotics, Shinshu University, Ueda, Nagano</wicri:regionArea>
<wicri:noRegion>Nagano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Fotopoulou, Christina" sort="Fotopoulou, Christina" uniqKey="Fotopoulou C" first="Christina" last="Fotopoulou">Christina Fotopoulou</name>
<affiliation wicri:level="3"><nlm:aff id="aff002"><addr-line>Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, Hammersmith Hospital, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, Hammersmith Hospital, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Moore, James E" sort="Moore, James E" uniqKey="Moore J" first="James E." last="Moore">James E. Moore</name>
<affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Bioengineering, Imperial College, London, South Kensington Campus, London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Bioengineering, Imperial College, London, South Kensington Campus, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">PLoS ONE</title>
<idno type="eISSN">1932-6203</idno>
<imprint><date when="2017">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>The lymphatic system has a major significance in the metastatic pathways in women’s cancers. Lymphatic pumping depends on both extrinsic and intrinsic mechanisms, and the mechanical behavior of lymphatic vessels regulates the function of the system. However, data on the mechanical properties and function of human lymphatics are lacking. Our aim is to characterize, for the first time, the passive biomechanical behavior of human collecting lymphatic vessels removed at pelvic lymph node dissection during primary debulking surgeries for epithelial ovarian cancer. Isolated vessels were cannulated and then pressurized at varying levels of applied axial stretch in a calcium-free Krebs buffer. Pressurized vessels were then imaged using multi-photon microscopy for collagen-elastin structural composition and fiber orientation. Both pressure-diameter and force-elongation responses were highly nonlinear, and axial stretching of the vessel served to decrease diameter at constant pressure. Pressure-diameter behavior for the human vessels is very similar to data from rat mesenteric vessels, though the human vessels were approximately 10× larger than those from rats. Multiphoton microscopy revealed the vessels to be composed of an inner layer of elastin with an outer layer of aligned collagen fibers. This is the first study that successfully described the passive biomechanical response and composition of human lymphatic vessels in patients with ovarian cancer. Future work should expand on this knowledge base with investigations of vessels from other anatomical locations, contractile behavior, and the implications on metastatic cell transport.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Gashev, Aa" uniqKey="Gashev A">AA Gashev</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Deng, X" uniqKey="Deng X">X Deng</name>
</author>
<author><name sortKey="Marinov, G" uniqKey="Marinov G">G Marinov</name>
</author>
<author><name sortKey="Marois, Y" uniqKey="Marois Y">Y Marois</name>
</author>
<author><name sortKey="Guidoin, R" uniqKey="Guidoin R">R Guidoin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rahbar, E" uniqKey="Rahbar E">E Rahbar</name>
</author>
<author><name sortKey="Weimer, J" uniqKey="Weimer J">J Weimer</name>
</author>
<author><name sortKey="Gibbs, H" uniqKey="Gibbs H">H Gibbs</name>
</author>
<author><name sortKey="Yeh, At" uniqKey="Yeh A">AT Yeh</name>
</author>
<author><name sortKey="Bertram, Cd" uniqKey="Bertram C">CD Bertram</name>
</author>
<author><name sortKey="Davis, Mj" uniqKey="Davis M">MJ Davis</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zhang, Rz" uniqKey="Zhang R">RZ Zhang</name>
</author>
<author><name sortKey="Gashev, Aa" uniqKey="Gashev A">AA Gashev</name>
</author>
<author><name sortKey="Zawieja, Dc" uniqKey="Zawieja D">DC Zawieja</name>
</author>
<author><name sortKey="Davis, Mj" uniqKey="Davis M">MJ Davis</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Davis, Mj" uniqKey="Davis M">MJ Davis</name>
</author>
<author><name sortKey="Rahbar, E" uniqKey="Rahbar E">E Rahbar</name>
</author>
<author><name sortKey="Gashev, Aa" uniqKey="Gashev A">AA Gashev</name>
</author>
<author><name sortKey="Zawieja, Dc" uniqKey="Zawieja D">DC Zawieja</name>
</author>
<author><name sortKey="Moore, Je Jr" uniqKey="Moore J">JE, Jr. Moore</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Scallan, Jp" uniqKey="Scallan J">JP Scallan</name>
</author>
<author><name sortKey="Zawieja, Sd" uniqKey="Zawieja S">SD Zawieja</name>
</author>
<author><name sortKey="Castorena Gonzalez, Ja" uniqKey="Castorena Gonzalez J">JA Castorena-Gonzalez</name>
</author>
<author><name sortKey="Davis, Mj" uniqKey="Davis M">MJ Davis</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kornuta, Ja" uniqKey="Kornuta J">JA Kornuta</name>
</author>
<author><name sortKey="Nepiyushchikh, Z" uniqKey="Nepiyushchikh Z">Z Nepiyushchikh</name>
</author>
<author><name sortKey="Gasheva, Oy" uniqKey="Gasheva O">OY Gasheva</name>
</author>
<author><name sortKey="Mukherjee, A" uniqKey="Mukherjee A">A Mukherjee</name>
</author>
<author><name sortKey="Zawieja, Dc" uniqKey="Zawieja D">DC Zawieja</name>
</author>
<author><name sortKey="Dixon, Jb" uniqKey="Dixon J">JB Dixon</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Padera, Tp" uniqKey="Padera T">TP Padera</name>
</author>
<author><name sortKey="Meijer, Ef" uniqKey="Meijer E">EF Meijer</name>
</author>
<author><name sortKey="Munn, Ll" uniqKey="Munn L">LL Munn</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Arkill, Kp" uniqKey="Arkill K">KP Arkill</name>
</author>
<author><name sortKey="Moger, J" uniqKey="Moger J">J Moger</name>
</author>
<author><name sortKey="Winlove, Cp" uniqKey="Winlove C">CP Winlove</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Caulk, Aw" uniqKey="Caulk A">AW Caulk</name>
</author>
<author><name sortKey="Nepiyushchikh, Zv" uniqKey="Nepiyushchikh Z">ZV Nepiyushchikh</name>
</author>
<author><name sortKey="Shaw, R" uniqKey="Shaw R">R Shaw</name>
</author>
<author><name sortKey="Dixon, Jb" uniqKey="Dixon J">JB Dixon</name>
</author>
<author><name sortKey="Gleason, Rl Jr" uniqKey="Gleason R">RL, Jr. Gleason</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zawieja, Dc" uniqKey="Zawieja D">DC Zawieja</name>
</author>
<author><name sortKey="Davis, Kl" uniqKey="Davis K">KL Davis</name>
</author>
<author><name sortKey="Schuster, R" uniqKey="Schuster R">R Schuster</name>
</author>
<author><name sortKey="Hinds, Wm" uniqKey="Hinds W">WM Hinds</name>
</author>
<author><name sortKey="Granger, Hj" uniqKey="Granger H">HJ Granger</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ohhashi, T" uniqKey="Ohhashi T">T Ohhashi</name>
</author>
<author><name sortKey="Azuma, T" uniqKey="Azuma T">T Azuma</name>
</author>
<author><name sortKey="Sakaguchi, M" uniqKey="Sakaguchi M">M Sakaguchi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Telinius, N" uniqKey="Telinius N">N Telinius</name>
</author>
<author><name sortKey="Drewsen, N" uniqKey="Drewsen N">N Drewsen</name>
</author>
<author><name sortKey="Pilegaard, H" uniqKey="Pilegaard H">H Pilegaard</name>
</author>
<author><name sortKey="Kold Petersen, H" uniqKey="Kold Petersen H">H Kold-Petersen</name>
</author>
<author><name sortKey="De Leval, M" uniqKey="De Leval M">M de Leval</name>
</author>
<author><name sortKey="Aalkjaer, C" uniqKey="Aalkjaer C">C Aalkjaer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bachmann, C" uniqKey="Bachmann C">C Bachmann</name>
</author>
<author><name sortKey="Bachmann, R" uniqKey="Bachmann R">R Bachmann</name>
</author>
<author><name sortKey="Kraemer, B" uniqKey="Kraemer B">B Kraemer</name>
</author>
<author><name sortKey="Brucker, Sy" uniqKey="Brucker S">SY Brucker</name>
</author>
<author><name sortKey="Staebler, A" uniqKey="Staebler A">A Staebler</name>
</author>
<author><name sortKey="Fend, F" uniqKey="Fend F">F Fend</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ledermann, Ja" uniqKey="Ledermann J">JA Ledermann</name>
</author>
<author><name sortKey="Raja, Fa" uniqKey="Raja F">FA Raja</name>
</author>
<author><name sortKey="Fotopoulou, C" uniqKey="Fotopoulou C">C Fotopoulou</name>
</author>
<author><name sortKey="Gonzalez Martin, A" uniqKey="Gonzalez Martin A">A Gonzalez-Martin</name>
</author>
<author><name sortKey="Colombo, N" uniqKey="Colombo N">N Colombo</name>
</author>
<author><name sortKey="Sessa, C" uniqKey="Sessa C">C Sessa</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schindelin, J" uniqKey="Schindelin J">J Schindelin</name>
</author>
<author><name sortKey="Arganda Carreras, I" uniqKey="Arganda Carreras I">I Arganda-Carreras</name>
</author>
<author><name sortKey="Frise, E" uniqKey="Frise E">E Frise</name>
</author>
<author><name sortKey="Kaynig, V" uniqKey="Kaynig V">V Kaynig</name>
</author>
<author><name sortKey="Longair, M" uniqKey="Longair M">M Longair</name>
</author>
<author><name sortKey="Pietzsch, T" uniqKey="Pietzsch T">T Pietzsch</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Fung, Yc" uniqKey="Fung Y">YC Fung</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Fung, Yc" uniqKey="Fung Y">YC Fung</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bertram, Cd" uniqKey="Bertram C">CD Bertram</name>
</author>
<author><name sortKey="Macaskill, C" uniqKey="Macaskill C">C Macaskill</name>
</author>
<author><name sortKey="Moore, Je Jr" uniqKey="Moore J">JE, Jr. Moore</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ayres, C" uniqKey="Ayres C">C Ayres</name>
</author>
<author><name sortKey="Bowlin, Gl" uniqKey="Bowlin G">GL Bowlin</name>
</author>
<author><name sortKey="Henderson, Sc" uniqKey="Henderson S">SC Henderson</name>
</author>
<author><name sortKey="Taylor, L" uniqKey="Taylor L">L Taylor</name>
</author>
<author><name sortKey="Shultz, J" uniqKey="Shultz J">J Shultz</name>
</author>
<author><name sortKey="Alexander, J" uniqKey="Alexander J">J Alexander</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Prat, J" uniqKey="Prat J">J Prat</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jamalian, S" uniqKey="Jamalian S">S Jamalian</name>
</author>
<author><name sortKey="Bertram, Cd" uniqKey="Bertram C">CD Bertram</name>
</author>
<author><name sortKey="Richardson, Wj" uniqKey="Richardson W">WJ Richardson</name>
</author>
<author><name sortKey="Moore, Je Jr" uniqKey="Moore J">JE, Jr. Moore</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zou, Y" uniqKey="Zou Y">Y Zou</name>
</author>
<author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chen, H" uniqKey="Chen H">H Chen</name>
</author>
<author><name sortKey="Slipchenko, Mn" uniqKey="Slipchenko M">MN Slipchenko</name>
</author>
<author><name sortKey="Liu, Y" uniqKey="Liu Y">Y Liu</name>
</author>
<author><name sortKey="Zhao, X" uniqKey="Zhao X">X Zhao</name>
</author>
<author><name sortKey="Cheng, Jx" uniqKey="Cheng J">JX Cheng</name>
</author>
<author><name sortKey="Lanir, Y" uniqKey="Lanir Y">Y Lanir</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
</listBibl>
</div1>
</back>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000090 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 000090 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= Main |étape= Merge |type= RBID |clé= PMC:5565099 |texte= The passive biomechanics of human pelvic collecting lymphatic vessels }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Merge/RBID.i -Sk "pubmed:28827843" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Merge/biblio.hfd \ | NlmPubMed2Wicri -a LymphedemaV1
This area was generated with Dilib version V0.6.31. |