LymphedemaV1, Main, Exploration, bibRecordById, pubmed:9550853

The LYMFASIM simulation program for modeling lymphatic filariasis and its control.

Identifieur interne : 00B053 ( Main/Exploration ); précédent : 00B052; suivant : 00B054

The LYMFASIM simulation program for modeling lymphatic filariasis and its control.

Auteurs : A P Plaisier [Pays-Bas] ; S. Subramanian ; P K Das ; W. Souza ; T. Lapa ; A F Furtado ; C P Van Der Ploeg ; J D Habbema ; G J Van Oortmarssen

Source :

Methods of information in medicine [ 0026-1270 ] ; 1998.

RBID : pubmed:9550853

Descripteurs français

KwdFr :
- Adolescent, Animaux, Brésil, Enfant, Enfant d'âge préscolaire, Femelle, Filariose lymphatique (), Filariose lymphatique (parasitologie), Filariose lymphatique (physiopathologie), Filariose lymphatique (épidémiologie), Humains, Modèles biologiques, Mâle, Nourrisson, Nouveau-né, Prise de décision assistée par ordinateur, Simulation numérique, Wuchereria bancrofti (physiologie).
MESH :
- parasitologie : Filariose lymphatique.
- physiologie : Wuchereria bancrofti.
- physiopathologie : Filariose lymphatique.
- épidémiologie : Filariose lymphatique.
- Adolescent, Animaux, Brésil, Enfant, Enfant d'âge préscolaire, Femelle, Filariose lymphatique, Humains, Modèles biologiques, Mâle, Nourrisson, Nouveau-né, Prise de décision assistée par ordinateur, Simulation numérique.
Wicri :
- geographic : Brésil.

English descriptors

KwdEn :
- Adolescent, Animals, Brazil, Child, Child, Preschool, Computer Simulation, Decision Making, Computer-Assisted, Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (parasitology), Elephantiasis, Filarial (physiopathology), Elephantiasis, Filarial (prevention & control), Female, Humans, Infant, Infant, Newborn, Male, Models, Biological, Wuchereria bancrofti (physiology).
MESH :
- geographic : Brazil.
- epidemiology : Elephantiasis, Filarial.
- parasitology : Elephantiasis, Filarial.
- physiology : Wuchereria bancrofti.
- physiopathology : Elephantiasis, Filarial.
- prevention & control : Elephantiasis, Filarial.
- Adolescent, Animals, Child, Child, Preschool, Computer Simulation, Decision Making, Computer-Assisted, Female, Humans, Infant, Infant, Newborn, Male, Models, Biological.

Abstract

The LYMFASIM modeling framework for the transmission and control of the tropical parasitic disease lymphatic filariasis is described and its use in the context of an endemic community in north-eastern Brazil is illustrated. Lymphatic filariasis is a disease with a complex natural history with many unknowns. This complicates decision making with respect to control strategies. With LYMFASIM, a variety of hypotheses can be tested about the life history of the parasite Wuchereria bancrofti, its transmission from man to man through mosquitoes, the role of the immune system in regulating parasite numbers, the development of disease symptoms, and the effects of control measures (drug treatment or mosquito control). The implications of alternative assumptions and uncertainty about the quantification of parameters for the effectiveness of control strategies can be investigated. Thanks to the use of stochastic microsimulation, LYMFASIM is highly flexible and can be adapted and extended as new knowledge emerges.

PubMed: 9550853

Affiliations:

Pays-Bas

Le document en format XML

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<front><div type="abstract" xml:lang="en">The LYMFASIM modeling framework for the transmission and control of the tropical parasitic disease lymphatic filariasis is described and its use in the context of an endemic community in north-eastern Brazil is illustrated. Lymphatic filariasis is a disease with a complex natural history with many unknowns. This complicates decision making with respect to control strategies. With LYMFASIM, a variety of hypotheses can be tested about the life history of the parasite Wuchereria bancrofti, its transmission from man to man through mosquitoes, the role of the immune system in regulating parasite numbers, the development of disease symptoms, and the effects of control measures (drug treatment or mosquito control). The implications of alternative assumptions and uncertainty about the quantification of parameters for the effectiveness of control strategies can be investigated. Thanks to the use of stochastic microsimulation, LYMFASIM is highly flexible and can be adapted and extended as new knowledge emerges.</div>
</front>
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Serveur d'exploration sur le lymphœdème

The LYMFASIM simulation program for modeling lymphatic filariasis and its control.

The LYMFASIM simulation program for modeling lymphatic filariasis and its control.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
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