Therapeutic Effect of Sirolimus for Lymphangioleiomyomatosis Remaining in the Abdominopelvic Region After Lung Transplantation: A Case Report.
Identifieur interne : 012909 ( Main/Exploration ); précédent : 012908; suivant : 012910Therapeutic Effect of Sirolimus for Lymphangioleiomyomatosis Remaining in the Abdominopelvic Region After Lung Transplantation: A Case Report.
Auteurs : T. Ito [Japon] ; M. Suno [Japon] ; K. Sakamoto [Japon] ; Y. Yoshizaki [Japon] ; K. Yamamoto [Japon] ; R. Nakanishi [Japon] ; Y. Hirano [Japon] ; M. Irie [Japon] ; T. Kurosaki [Japon] ; S. Otani [Japon] ; M. Yamane [Japon] ; S. Sugimoto [Japon] ; K. Miyoshi [Japon] ; T. Oto [Japon]Source :
- Transplantation proceedings [ 1873-2623 ]
Descripteurs français
- KwdFr :
- Abdomen (anatomopathologie), Acide mycophénolique (analogues et dérivés), Acide mycophénolique (usage thérapeutique), Adulte, Femelle, Humains, Immunosuppresseurs (usage thérapeutique), Immunosuppression thérapeutique (), Lymphangioléiomyomatose (), Lymphangioléiomyomatose (anatomopathologie), Lymphangioléiomyomatose (traitement médicamenteux), Lymphoedème (traitement médicamenteux), Lymphoedème (étiologie), Maladie résiduelle, Pelvis (anatomopathologie), Prednisolone (usage thérapeutique), Qualité de vie, Sirolimus (usage thérapeutique), Tacrolimus (usage thérapeutique), Transplantation pulmonaire, Tumeurs du poumon (anatomopathologie), Tumeurs du poumon (traitement médicamenteux).
- MESH :
- analogues et dérivés : Acide mycophénolique.
- anatomopathologie : Abdomen, Lymphangioléiomyomatose, Pelvis, Tumeurs du poumon.
- traitement médicamenteux : Lymphangioléiomyomatose, Lymphoedème, Tumeurs du poumon.
- usage thérapeutique : Acide mycophénolique, Immunosuppresseurs, Prednisolone, Sirolimus, Tacrolimus.
- étiologie : Lymphoedème.
- Adulte, Femelle, Humains, Immunosuppression thérapeutique, Lymphangioléiomyomatose, Maladie résiduelle, Qualité de vie, Transplantation pulmonaire.
English descriptors
- KwdEn :
- Abdomen (pathology), Adult, Female, Humans, Immunosuppression (methods), Immunosuppressive Agents (therapeutic use), Lung Neoplasms (drug therapy), Lung Neoplasms (pathology), Lung Transplantation, Lymphangioleiomyomatosis (drug therapy), Lymphangioleiomyomatosis (pathology), Lymphangioleiomyomatosis (surgery), Lymphedema (drug therapy), Lymphedema (etiology), Mycophenolic Acid (analogs & derivatives), Mycophenolic Acid (therapeutic use), Neoplasm, Residual, Pelvis (pathology), Prednisolone (therapeutic use), Quality of Life, Sirolimus (therapeutic use), Tacrolimus (therapeutic use).
- MESH :
- chemical , analogs & derivatives : Mycophenolic Acid.
- chemical , therapeutic use : Immunosuppressive Agents, Mycophenolic Acid, Prednisolone, Sirolimus, Tacrolimus.
- drug therapy : Lung Neoplasms, Lymphangioleiomyomatosis, Lymphedema.
- etiology : Lymphedema.
- methods : Immunosuppression.
- pathology : Abdomen, Lung Neoplasms, Lymphangioleiomyomatosis, Pelvis.
- surgery : Lymphangioleiomyomatosis.
- Adult, Female, Humans, Lung Transplantation, Neoplasm, Residual, Quality of Life.
Abstract
Sirolimus (SRL) is used to treat pulmonary lymphangioleiomyomatosis (P-LAM). There is limited evidence that SRL has systemic efficacy for the patients with extrapulmonary lymphangioleiomyomatosis (E-LAM) remaining after lung transplantation (LT) for P-LAM. This report examines the efficacy of SRL treatment for the patient with E-LAM remaining after an LT for P-LAM.
DOI: 10.1016/j.transproceed.2015.12.021
PubMed: 26915883
Affiliations:
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Ito</name><affiliation wicri:level="1"><nlm:affiliation>Division of Oncology Pharmaceutical Care & Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oncology Pharmaceutical Care & Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University</wicri:regionArea><wicri:noRegion>Okayama University</wicri:noRegion></affiliation></author><author><name sortKey="Suno, M" sort="Suno, M" uniqKey="Suno M" first="M" last="Suno">M. Suno</name><affiliation wicri:level="1"><nlm:affiliation>Division of Oncology Pharmaceutical Care & Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Japan. Electronic address: sunoma@pharm.okayama-u.ac.jp.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oncology Pharmaceutical Care & Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University</wicri:regionArea><wicri:noRegion>Okayama University</wicri:noRegion></affiliation></author><author><name sortKey="Sakamoto, K" sort="Sakamoto, K" uniqKey="Sakamoto K" first="K" last="Sakamoto">K. Sakamoto</name><affiliation wicri:level="1"><nlm:affiliation>Division of Oncology Pharmaceutical Care & Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oncology Pharmaceutical Care & Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University</wicri:regionArea><wicri:noRegion>Okayama University</wicri:noRegion></affiliation></author><author><name sortKey="Yoshizaki, Y" sort="Yoshizaki, Y" uniqKey="Yoshizaki Y" first="Y" last="Yoshizaki">Y. Yoshizaki</name><affiliation wicri:level="1"><nlm:affiliation>Division of Oncology Pharmaceutical Care & Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oncology Pharmaceutical Care & Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University</wicri:regionArea><wicri:noRegion>Okayama University</wicri:noRegion></affiliation></author><author><name sortKey="Yamamoto, K" sort="Yamamoto, K" uniqKey="Yamamoto K" first="K" last="Yamamoto">K. Yamamoto</name><affiliation wicri:level="1"><nlm:affiliation>Division of Oncology Pharmaceutical Care & Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oncology Pharmaceutical Care & Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University</wicri:regionArea><wicri:noRegion>Okayama University</wicri:noRegion></affiliation></author><author><name sortKey="Nakanishi, R" sort="Nakanishi, R" uniqKey="Nakanishi R" first="R" last="Nakanishi">R. Nakanishi</name><affiliation wicri:level="1"><nlm:affiliation>Division of Oncology Pharmaceutical Care & Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Oncology Pharmaceutical Care & Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University</wicri:regionArea><wicri:noRegion>Okayama University</wicri:noRegion></affiliation></author><author><name sortKey="Hirano, Y" sort="Hirano, Y" uniqKey="Hirano Y" first="Y" last="Hirano">Y. Hirano</name><affiliation wicri:level="1"><nlm:affiliation>Department of Thoracic Surgery, Okayama University Hospital, Okayama, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Thoracic Surgery, Okayama University Hospital, Okayama</wicri:regionArea><wicri:noRegion>Okayama</wicri:noRegion></affiliation></author><author><name sortKey="Irie, M" sort="Irie, M" uniqKey="Irie M" first="M" last="Irie">M. Irie</name><affiliation wicri:level="1"><nlm:affiliation>Department of Thoracic Surgery, Okayama University Hospital, Okayama, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Thoracic Surgery, Okayama University Hospital, Okayama</wicri:regionArea><wicri:noRegion>Okayama</wicri:noRegion></affiliation></author><author><name sortKey="Kurosaki, T" sort="Kurosaki, T" uniqKey="Kurosaki T" first="T" last="Kurosaki">T. Kurosaki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Thoracic Surgery, Okayama University Hospital, Okayama, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Thoracic Surgery, Okayama University Hospital, Okayama</wicri:regionArea><wicri:noRegion>Okayama</wicri:noRegion></affiliation></author><author><name sortKey="Otani, S" sort="Otani, S" uniqKey="Otani S" first="S" last="Otani">S. Otani</name><affiliation wicri:level="1"><nlm:affiliation>Department of Thoracic Surgery, Okayama University Hospital, Okayama, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Thoracic Surgery, Okayama University Hospital, Okayama</wicri:regionArea><wicri:noRegion>Okayama</wicri:noRegion></affiliation></author><author><name sortKey="Yamane, M" sort="Yamane, M" uniqKey="Yamane M" first="M" last="Yamane">M. Yamane</name><affiliation wicri:level="1"><nlm:affiliation>Department of Thoracic Surgery, Okayama University Hospital, Okayama, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Thoracic Surgery, Okayama University Hospital, Okayama</wicri:regionArea><wicri:noRegion>Okayama</wicri:noRegion></affiliation></author><author><name sortKey="Sugimoto, S" sort="Sugimoto, S" uniqKey="Sugimoto S" first="S" last="Sugimoto">S. Sugimoto</name><affiliation wicri:level="1"><nlm:affiliation>Department of Thoracic Surgery, Okayama University Hospital, Okayama, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Thoracic Surgery, Okayama University Hospital, Okayama</wicri:regionArea><wicri:noRegion>Okayama</wicri:noRegion></affiliation></author><author><name sortKey="Miyoshi, K" sort="Miyoshi, K" uniqKey="Miyoshi K" first="K" last="Miyoshi">K. Miyoshi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Thoracic Surgery, Okayama University Hospital, Okayama, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Thoracic Surgery, Okayama University Hospital, Okayama</wicri:regionArea><wicri:noRegion>Okayama</wicri:noRegion></affiliation></author><author><name sortKey="Oto, T" sort="Oto, T" uniqKey="Oto T" first="T" last="Oto">T. Oto</name><affiliation wicri:level="1"><nlm:affiliation>Department of Thoracic Surgery, Okayama University Hospital, Okayama, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Thoracic Surgery, Okayama University Hospital, Okayama</wicri:regionArea><wicri:noRegion>Okayama</wicri:noRegion></affiliation></author></analytic><series><title level="j">Transplantation proceedings</title><idno type="eISSN">1873-2623</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Abdomen (pathology)</term><term>Adult</term><term>Female</term><term>Humans</term><term>Immunosuppression (methods)</term><term>Immunosuppressive Agents (therapeutic use)</term><term>Lung Neoplasms (drug therapy)</term><term>Lung Neoplasms (pathology)</term><term>Lung Transplantation</term><term>Lymphangioleiomyomatosis (drug therapy)</term><term>Lymphangioleiomyomatosis (pathology)</term><term>Lymphangioleiomyomatosis (surgery)</term><term>Lymphedema (drug therapy)</term><term>Lymphedema (etiology)</term><term>Mycophenolic Acid (analogs & derivatives)</term><term>Mycophenolic Acid (therapeutic use)</term><term>Neoplasm, Residual</term><term>Pelvis (pathology)</term><term>Prednisolone (therapeutic use)</term><term>Quality of Life</term><term>Sirolimus (therapeutic use)</term><term>Tacrolimus (therapeutic use)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Abdomen (anatomopathologie)</term><term>Acide mycophénolique (analogues et dérivés)</term><term>Acide mycophénolique (usage thérapeutique)</term><term>Adulte</term><term>Femelle</term><term>Humains</term><term>Immunosuppresseurs (usage thérapeutique)</term><term>Immunosuppression thérapeutique ()</term><term>Lymphangioléiomyomatose ()</term><term>Lymphangioléiomyomatose (anatomopathologie)</term><term>Lymphangioléiomyomatose (traitement médicamenteux)</term><term>Lymphoedème (traitement médicamenteux)</term><term>Lymphoedème (étiologie)</term><term>Maladie résiduelle</term><term>Pelvis (anatomopathologie)</term><term>Prednisolone (usage thérapeutique)</term><term>Qualité de vie</term><term>Sirolimus (usage thérapeutique)</term><term>Tacrolimus (usage thérapeutique)</term><term>Transplantation pulmonaire</term><term>Tumeurs du poumon (anatomopathologie)</term><term>Tumeurs du poumon (traitement médicamenteux)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Mycophenolic Acid</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Immunosuppressive Agents</term><term>Mycophenolic Acid</term><term>Prednisolone</term><term>Sirolimus</term><term>Tacrolimus</term></keywords><keywords scheme="MESH" qualifier="analogues et dérivés" xml:lang="fr"><term>Acide mycophénolique</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Abdomen</term><term>Lymphangioléiomyomatose</term><term>Pelvis</term><term>Tumeurs du poumon</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Lung Neoplasms</term><term>Lymphangioleiomyomatosis</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Immunosuppression</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Abdomen</term><term>Lung Neoplasms</term><term>Lymphangioleiomyomatosis</term><term>Pelvis</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Lymphangioleiomyomatosis</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Lymphangioléiomyomatose</term><term>Lymphoedème</term><term>Tumeurs du poumon</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Acide mycophénolique</term><term>Immunosuppresseurs</term><term>Prednisolone</term><term>Sirolimus</term><term>Tacrolimus</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Lymphoedème</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Female</term><term>Humans</term><term>Lung Transplantation</term><term>Neoplasm, Residual</term><term>Quality of Life</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Femelle</term><term>Humains</term><term>Immunosuppression thérapeutique</term><term>Lymphangioléiomyomatose</term><term>Maladie résiduelle</term><term>Qualité de vie</term><term>Transplantation pulmonaire</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Sirolimus (SRL) is used to treat pulmonary lymphangioleiomyomatosis (P-LAM). There is limited evidence that SRL has systemic efficacy for the patients with extrapulmonary lymphangioleiomyomatosis (E-LAM) remaining after lung transplantation (LT) for P-LAM. This report examines the efficacy of SRL treatment for the patient with E-LAM remaining after an LT for P-LAM.</div></front></TEI><affiliations><list><country><li>Japon</li></country></list><tree><country name="Japon"><noRegion><name sortKey="Ito, T" sort="Ito, T" uniqKey="Ito T" first="T" last="Ito">T. Ito</name></noRegion><name sortKey="Hirano, Y" sort="Hirano, Y" uniqKey="Hirano Y" first="Y" last="Hirano">Y. Hirano</name><name sortKey="Irie, M" sort="Irie, M" uniqKey="Irie M" first="M" last="Irie">M. Irie</name><name sortKey="Kurosaki, T" sort="Kurosaki, T" uniqKey="Kurosaki T" first="T" last="Kurosaki">T. Kurosaki</name><name sortKey="Miyoshi, K" sort="Miyoshi, K" uniqKey="Miyoshi K" first="K" last="Miyoshi">K. Miyoshi</name><name sortKey="Nakanishi, R" sort="Nakanishi, R" uniqKey="Nakanishi R" first="R" last="Nakanishi">R. Nakanishi</name><name sortKey="Otani, S" sort="Otani, S" uniqKey="Otani S" first="S" last="Otani">S. Otani</name><name sortKey="Oto, T" sort="Oto, T" uniqKey="Oto T" first="T" last="Oto">T. Oto</name><name sortKey="Sakamoto, K" sort="Sakamoto, K" uniqKey="Sakamoto K" first="K" last="Sakamoto">K. Sakamoto</name><name sortKey="Sugimoto, S" sort="Sugimoto, S" uniqKey="Sugimoto S" first="S" last="Sugimoto">S. Sugimoto</name><name sortKey="Suno, M" sort="Suno, M" uniqKey="Suno M" first="M" last="Suno">M. Suno</name><name sortKey="Yamamoto, K" sort="Yamamoto, K" uniqKey="Yamamoto K" first="K" last="Yamamoto">K. Yamamoto</name><name sortKey="Yamane, M" sort="Yamane, M" uniqKey="Yamane M" first="M" last="Yamane">M. Yamane</name><name sortKey="Yoshizaki, Y" sort="Yoshizaki, Y" uniqKey="Yoshizaki Y" first="Y" last="Yoshizaki">Y. Yoshizaki</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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