Lymphoedema in urological cancer
Identifieur interne : 008D11 ( Main/Exploration ); précédent : 008D10; suivant : 008D12Lymphoedema in urological cancer
Auteurs : A. A. Okeke [Royaume-Uni] ; D. O. Bates [Royaume-Uni] ; D. A. Gillatt [Royaume-Uni]Source :
- European urology [ 0302-2838 ] ; 2004.
Descripteurs français
- KwdFr :
- Appareil urogénital (physiologie), Humains, Jambe, Lymphoedème (), Lymphoedème (diagnostic), Lymphoedème (épidémiologie), Lymphoedème (étiologie), Maladies de l'appareil génital mâle (), Maladies de l'appareil génital mâle (diagnostic), Maladies de l'appareil génital mâle (épidémiologie), Maladies de l'appareil génital mâle (étiologie), Mâle, Prévalence, Tumeurs urologiques ().
- MESH :
- diagnostic : Lymphoedème, Maladies de l'appareil génital mâle.
- physiologie : Appareil urogénital.
- épidémiologie : Lymphoedème, Maladies de l'appareil génital mâle.
- étiologie : Lymphoedème, Maladies de l'appareil génital mâle.
- Pascal (Inist)
English descriptors
- KwdEn :
- Genital Diseases, Male (diagnosis), Genital Diseases, Male (epidemiology), Genital Diseases, Male (etiology), Genital Diseases, Male (therapy), Humans, Incidence, Leg, Lymphedema, Lymphedema (diagnosis), Lymphedema (epidemiology), Lymphedema (etiology), Lymphedema (therapy), Male, Malignant tumor, Nephrology, Pathophysiology, Prevalence, Treatment, Urogenital System (physiology), Urologic Neoplasms (complications), Urology.
- MESH :
- complications : Urologic Neoplasms.
- diagnosis : Genital Diseases, Male, Lymphedema.
- epidemiology : Genital Diseases, Male, Lymphedema.
- etiology : Genital Diseases, Male, Lymphedema.
- physiology : Urogenital System.
- therapy : Genital Diseases, Male, Lymphedema.
- Humans, Leg, Male, Prevalence.
Abstract
Objectives: To review the evidence underlying the diagnosis, pathology and treatment of lymphoedema of the lower extremities and genitalia from or following the treatment for urological cancer, and to suggest possible underlying pathophysiological mechanisms that may explain its development. Methods: Reviews of the epidemiological, surgical, and scientific literature and personal experience of treatment of patients are used to build a picture of clinical setting and the physiological principles underlying lymphoedema of the leg. Results: Lymphoedema of the leg and genitals results in serious morbidity for the patient. The incidence is largely unknown, but varies according to the type and location of tumours and may be up to 50% in advanced stages of penile carcinoma, or following its treatment. Although the aetiology of the condition is either iatrogenic, or associated with malignancy, the underlying pathophysiology is not well understood. Conclusions: Recent studies in breast cancer related lymphoedema point to underlying vascular as well as lymphatic problems, but the parallels with lower limb lymphoedema are not known.
Affiliations:
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Le document en format XML
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A." last="Okeke">A. A. Okeke</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Bristol Urological Institute, Southmead Hospital, Westbury-on-Trym</s1><s2>Bristol BS10 5NB</s2><s3>GBR</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Bristol BS10 5NB</wicri:noRegion></affiliation></author><author><name sortKey="Bates, D O" sort="Bates, D O" uniqKey="Bates D" first="D. O." last="Bates">D. O. Bates</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Microvascular Research Laboratories, Department of Physiology, Preclinical Veterinary School, University of Bristol, Southwell Street</s1><s2>Bristol BS2 8EJ</s2><s3>GBR</s3><sZ>2 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Bristol BS2 8EJ</wicri:noRegion></affiliation></author><author><name sortKey="Gillatt, D A" sort="Gillatt, D A" uniqKey="Gillatt D" first="D. A." last="Gillatt">D. A. Gillatt</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Bristol Urological Institute, Southmead Hospital, Westbury-on-Trym</s1><s2>Bristol BS10 5NB</s2><s3>GBR</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Bristol BS10 5NB</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">European urology</title><title level="j" type="abbreviated">Eur. urol.</title><idno type="ISSN">0302-2838</idno><imprint><date when="2004">2004</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">European urology</title><title level="j" type="abbreviated">Eur. urol.</title><idno type="ISSN">0302-2838</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Genital Diseases, Male (diagnosis)</term><term>Genital Diseases, Male (epidemiology)</term><term>Genital Diseases, Male (etiology)</term><term>Genital Diseases, Male (therapy)</term><term>Humans</term><term>Incidence</term><term>Leg</term><term>Lymphedema</term><term>Lymphedema (diagnosis)</term><term>Lymphedema (epidemiology)</term><term>Lymphedema (etiology)</term><term>Lymphedema (therapy)</term><term>Male</term><term>Malignant tumor</term><term>Nephrology</term><term>Pathophysiology</term><term>Prevalence</term><term>Treatment</term><term>Urogenital System (physiology)</term><term>Urologic Neoplasms (complications)</term><term>Urology</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Appareil urogénital (physiologie)</term><term>Humains</term><term>Jambe</term><term>Lymphoedème ()</term><term>Lymphoedème (diagnostic)</term><term>Lymphoedème (épidémiologie)</term><term>Lymphoedème (étiologie)</term><term>Maladies de l'appareil génital mâle ()</term><term>Maladies de l'appareil génital mâle (diagnostic)</term><term>Maladies de l'appareil génital mâle (épidémiologie)</term><term>Maladies de l'appareil génital mâle (étiologie)</term><term>Mâle</term><term>Prévalence</term><term>Tumeurs urologiques ()</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Urologic Neoplasms</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Genital Diseases, Male</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Lymphoedème</term><term>Maladies de l'appareil génital mâle</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Genital Diseases, Male</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Genital Diseases, Male</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Appareil urogénital</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Urogenital System</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Genital Diseases, Male</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Lymphoedème</term><term>Maladies de l'appareil génital mâle</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Lymphoedème</term><term>Maladies de l'appareil génital mâle</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Leg</term><term>Male</term><term>Prevalence</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Humains</term><term>Jambe</term><term>Lymphoedème</term><term>Maladies de l'appareil génital mâle</term><term>Mâle</term><term>Prévalence</term><term>Tumeur maligne</term><term>Incidence</term><term>Physiopathologie</term><term>Traitement</term><term>Tumeurs urologiques</term><term>Urologie</term><term>Néphrologie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objectives: To review the evidence underlying the diagnosis, pathology and treatment of lymphoedema of the lower extremities and genitalia from or following the treatment for urological cancer, and to suggest possible underlying pathophysiological mechanisms that may explain its development. Methods: Reviews of the epidemiological, surgical, and scientific literature and personal experience of treatment of patients are used to build a picture of clinical setting and the physiological principles underlying lymphoedema of the leg. Results: Lymphoedema of the leg and genitals results in serious morbidity for the patient. The incidence is largely unknown, but varies according to the type and location of tumours and may be up to 50% in advanced stages of penile carcinoma, or following its treatment. Although the aetiology of the condition is either iatrogenic, or associated with malignancy, the underlying pathophysiology is not well understood. Conclusions: Recent studies in breast cancer related lymphoedema point to underlying vascular as well as lymphatic problems, but the parallels with lower limb lymphoedema are not known.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Okeke, A A" sort="Okeke, A A" uniqKey="Okeke A" first="A. A." last="Okeke">A. A. Okeke</name></noRegion><name sortKey="Bates, D O" sort="Bates, D O" uniqKey="Bates D" first="D. O." last="Bates">D. O. Bates</name><name sortKey="Gillatt, D A" sort="Gillatt, D A" uniqKey="Gillatt D" first="D. A." last="Gillatt">D. A. Gillatt</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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