Lymphatic function is required prenatally for lung inflation at birth
Identifieur interne : 002898 ( Main/Exploration ); précédent : 002897; suivant : 002899Lymphatic function is required prenatally for lung inflation at birth
Auteurs : Zoltán Jakus ; Jason P. Gleghorn ; David R. Enis ; Aslihan Sen ; Stephanie Chia ; Xi Liu ; David R. Rawnsley ; Yiqing Yang ; Paul R. Hess ; Zhiying Zou ; Jisheng Yang ; Susan H. Guttentag ; Celeste M. Nelson ; Mark L. KahnSource :
- The Journal of Experimental Medicine [ 0022-1007 ] ; 2014.
Abstract
Neonatal mice lacking lymphatic vessels due to loss of lymphangiogenic factor CCBE1 or VEGFR3 function fail to inflate their lungs, suggestive of respiratory failure in infants with congenital pulmonary lymphangiectasia.
Url:
DOI: 10.1084/jem.20132308
PubMed: 24733830
PubMed Central: 4010903
Affiliations:
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<front><div type="abstract" xml:lang="en"><p>Neonatal mice lacking lymphatic vessels due to loss of lymphangiogenic factor CCBE1 or VEGFR3 function fail to inflate their lungs, suggestive of respiratory failure in infants with congenital pulmonary lymphangiectasia.</p>
</div>
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<tree><noCountry><name sortKey="Chia, Stephanie" sort="Chia, Stephanie" uniqKey="Chia S" first="Stephanie" last="Chia">Stephanie Chia</name>
<name sortKey="Enis, David R" sort="Enis, David R" uniqKey="Enis D" first="David R." last="Enis">David R. Enis</name>
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