In vivo three-dimensional photoacoustic imaging based on a clinical matrix array ultrasound probe
Identifieur interne : 004584 ( Main/Exploration ); précédent : 004583; suivant : 004585In vivo three-dimensional photoacoustic imaging based on a clinical matrix array ultrasound probe
Auteurs : Yu Wang [États-Unis] ; Todd N. Erpelding [États-Unis] ; Ladislav Jankovic [États-Unis] ; Zijian Guo [États-Unis] ; Jean-Luc Robert [États-Unis] ; Guillaume David [États-Unis] ; Lihong V. Wang [États-Unis]Source :
- Journal of Biomedical Optics [ 1083-3668 ] ; 2012.
Abstract
We present an integrated photoacoustic and ultrasonic three-dimensional (3-D) volumetric imaging system based on a two-dimensional (2-D) matrix array ultrasound probe. A wavelength-tunable dye laser pumped by a
Url:
DOI: 10.1117/1.JBO.17.6.061208
PubMed: 22734738
PubMed Central: 3380932
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><title>Abstract.</title>
<p>We present an integrated photoacoustic and ultrasonic three-dimensional (3-D) volumetric imaging system based on a two-dimensional (2-D) matrix array ultrasound probe. A wavelength-tunable dye laser pumped by a <inline-formula><mml:math id="M1"><mml:mrow><mml:mi>Q</mml:mi>
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-switched Nd:YAG laser serves as the light source and a modified commercial ultrasound imaging system (iU22, Philips Healthcare) with a 2-D array transducer (X7-2, Philips Healthcare) detects both the pulse-echo ultrasound and photoacoustic signals. A multichannel data acquisition system acquires the RF channel data. The imaging system enables rendering of co-registered 3-D ultrasound and photoacoustic images without mechanical scanning. The resolution along the azimuth, elevation, and axial direction are measured to be 0.69, 0.90 and 0.84 mm for photoacoustic imaging. <italic>In vivo</italic>
3-D photoacoustic mapping of the sentinel lymph node was demonstrated in a rat model using methylene blue dye. These results highlight the clinical potential of 3-D PA imaging for identification of sentinel lymph nodes for cancer staging in humans.</p>
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<name sortKey="Erpelding, Todd N" sort="Erpelding, Todd N" uniqKey="Erpelding T" first="Todd N." last="Erpelding">Todd N. Erpelding</name>
<name sortKey="Guo, Zijian" sort="Guo, Zijian" uniqKey="Guo Z" first="Zijian" last="Guo">Zijian Guo</name>
<name sortKey="Jankovic, Ladislav" sort="Jankovic, Ladislav" uniqKey="Jankovic L" first="Ladislav" last="Jankovic">Ladislav Jankovic</name>
<name sortKey="Robert, Jean Luc" sort="Robert, Jean Luc" uniqKey="Robert J" first="Jean-Luc" last="Robert">Jean-Luc Robert</name>
<name sortKey="Wang, Lihong V" sort="Wang, Lihong V" uniqKey="Wang L" first="Lihong V." last="Wang">Lihong V. Wang</name>
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