Lymphatic flow in humans as indicated by the clearance of 125I-labeled albumin from the subcutaneous tissue of the leg
Identifieur interne : 00F448 ( Main/Exploration ); précédent : 00F447; suivant : 00F449Lymphatic flow in humans as indicated by the clearance of 125I-labeled albumin from the subcutaneous tissue of the leg
Auteurs : M. J. Fernandez [Royaume-Uni] ; W. T. Davies [États-Unis] ; G. M. Owen [Royaume-Uni] ; A. Tyler [Royaume-Uni]Source :
- Journal of Surgical Research [ 0022-4804 ] ; 1983.
Abstract
Since the removal of albumin from the extracellular space and its return to the vascular compartment is the essential function of the lymphatic system, the rate at which it is removed from the interstitial tissue may be regarded as a means of estimating lymphatic efficiency. An objective measure of lymphatic function can be obtained by monitoring the rate of clearance following injection of 125I-labeled albumin (RIHSA) from the subcutaneous tissue of a limb. The clearance of 125I-RIHSA from the lower limb was monitored in a group of patients with normal limbs, patients with unilateral edema due to deep vein thrombosis, and patients with bilateral edema due to hypoproteinemia. The mean T12 in normal legs was 32.7 hr, compared to 23.7 hr in edematous limbs due to deep vein thrombosis and 19.4 in edematous limbs due to hypoproteinemia. There is a clear-cut difference in clearance rate between edematous and nonedematous limbs. This suggests that lymphatic flow is increased in edema due to venous obstruction and hypoproteinemia.
Url:
DOI: 10.1016/0022-4804(83)90131-2
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 006E76
- to stream Istex, to step Curation: 006E76
- to stream Istex, to step Checkpoint: 006210
- to stream Main, to step Merge: 010345
- to stream Main, to step Curation: 00F448
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Lymphatic flow in humans as indicated by the clearance of 125I-labeled albumin from the subcutaneous tissue of the leg</title><author><name sortKey="Fernandez, M J" sort="Fernandez, M J" uniqKey="Fernandez M" first="M. J." last="Fernandez">M. J. Fernandez</name></author><author><name sortKey="Davies, W T" sort="Davies, W T" uniqKey="Davies W" first="W. T." last="Davies">W. T. Davies</name></author><author><name sortKey="Owen, G M" sort="Owen, G M" uniqKey="Owen G" first="G. M." last="Owen">G. M. Owen</name></author><author><name sortKey="Tyler, A" sort="Tyler, A" uniqKey="Tyler A" first="A." last="Tyler">A. Tyler</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:EC2A1A2DB909C463AA85EB1BFF19AEABBA0A2FC9</idno><date when="1983" year="1983">1983</date><idno type="doi">10.1016/0022-4804(83)90131-2</idno><idno type="url">https://api.istex.fr/document/EC2A1A2DB909C463AA85EB1BFF19AEABBA0A2FC9/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">006E76</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">006E76</idno><idno type="wicri:Area/Istex/Curation">006E76</idno><idno type="wicri:Area/Istex/Checkpoint">006210</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">006210</idno><idno type="wicri:doubleKey">0022-4804:1983:Fernandez M:lymphatic:flow:in</idno><idno type="wicri:Area/Main/Merge">010345</idno><idno type="wicri:Area/Main/Curation">00F448</idno><idno type="wicri:Area/Main/Exploration">00F448</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Lymphatic flow in humans as indicated by the clearance of 125I-labeled albumin from the subcutaneous tissue of the leg</title><author><name sortKey="Fernandez, M J" sort="Fernandez, M J" uniqKey="Fernandez M" first="M. J." last="Fernandez">M. J. Fernandez</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Surgery, Welsh National School of Medicine, Heath Park, Cardiff, CF4 4XN Wales</wicri:regionArea><wicri:noRegion>CF4 4XN Wales</wicri:noRegion></affiliation></author><author><name sortKey="Davies, W T" sort="Davies, W T" uniqKey="Davies W" first="W. T." last="Davies">W. T. Davies</name><affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Surgery, Columbus Hospital, 2520 North Lakeview Avenue, Chicago, Illinois 60614</wicri:regionArea><wicri:noRegion>Illinois 60614</wicri:noRegion></affiliation></author><author><name sortKey="Owen, G M" sort="Owen, G M" uniqKey="Owen G" first="G. M." last="Owen">G. M. Owen</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Medical Physics, Welsh National School of Medicine, Heath Park, Cardiff, CF4 4XN Wales</wicri:regionArea><wicri:noRegion>CF4 4XN Wales</wicri:noRegion></affiliation></author><author><name sortKey="Tyler, A" sort="Tyler, A" uniqKey="Tyler A" first="A." last="Tyler">A. Tyler</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Medical Physics, Welsh National School of Medicine, Heath Park, Cardiff, CF4 4XN Wales</wicri:regionArea><wicri:noRegion>CF4 4XN Wales</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Surgical Research</title><title level="j" type="abbrev">YJSRE</title><idno type="ISSN">0022-4804</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1983">1983</date><biblScope unit="volume">35</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="101">101</biblScope><biblScope unit="page" to="104">104</biblScope></imprint><idno type="ISSN">0022-4804</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0022-4804</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Since the removal of albumin from the extracellular space and its return to the vascular compartment is the essential function of the lymphatic system, the rate at which it is removed from the interstitial tissue may be regarded as a means of estimating lymphatic efficiency. An objective measure of lymphatic function can be obtained by monitoring the rate of clearance following injection of 125I-labeled albumin (RIHSA) from the subcutaneous tissue of a limb. The clearance of 125I-RIHSA from the lower limb was monitored in a group of patients with normal limbs, patients with unilateral edema due to deep vein thrombosis, and patients with bilateral edema due to hypoproteinemia. The mean T12 in normal legs was 32.7 hr, compared to 23.7 hr in edematous limbs due to deep vein thrombosis and 19.4 in edematous limbs due to hypoproteinemia. There is a clear-cut difference in clearance rate between edematous and nonedematous limbs. This suggests that lymphatic flow is increased in edema due to venous obstruction and hypoproteinemia.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li><li>États-Unis</li></country></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Fernandez, M J" sort="Fernandez, M J" uniqKey="Fernandez M" first="M. J." last="Fernandez">M. J. Fernandez</name></noRegion><name sortKey="Owen, G M" sort="Owen, G M" uniqKey="Owen G" first="G. M." last="Owen">G. M. Owen</name><name sortKey="Tyler, A" sort="Tyler, A" uniqKey="Tyler A" first="A." last="Tyler">A. Tyler</name></country><country name="États-Unis"><noRegion><name sortKey="Davies, W T" sort="Davies, W T" uniqKey="Davies W" first="W. T." last="Davies">W. T. Davies</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 00F448 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 00F448 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:EC2A1A2DB909C463AA85EB1BFF19AEABBA0A2FC9
|texte= Lymphatic flow in humans as indicated by the clearance of 125I-labeled albumin from the subcutaneous tissue of the leg
}}
| This area was generated with Dilib version V0.6.31. |  |