Serveur d'exploration sur le lymphœdème

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Regulation of immune responses in lymphatic filariasis.

Identifieur interne : 00E596 ( Main/Exploration ); précédent : 00E595; suivant : 00E597

Regulation of immune responses in lymphatic filariasis.

Auteurs : W F Piessens ; A A Wadee ; L. Kurniawan

Source :

RBID : pubmed:2954794

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English descriptors

Abstract

The nature and intensity of immune reactions to filarial antigens appear to be controlled by two broad mechanisms: immunoregulation and immune tolerance. Parasite molecules of high molecular weight activate suppressor T lymphocytes; suppressive parasite products are present in sera from microfilaraemic patients. Prenatal or perinatal exposure to soluble parasite antigens may influence a person's future ability to react to filarial antigens.

PubMed: 2954794


Affiliations:


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Le document en format XML

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<term>Animals</term>
<term>Antibody Formation</term>
<term>Antigens, Helminth (immunology)</term>
<term>Brugia (immunology)</term>
<term>Elephantiasis, Filarial (immunology)</term>
<term>Humans</term>
<term>Immune Tolerance</term>
<term>Immunity, Cellular</term>
<term>Immunoglobulin G (biosynthesis)</term>
<term>Immunoglobulin M (biosynthesis)</term>
<term>Lymphedema (immunology)</term>
<term>Lymphocyte Activation</term>
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<term>Activation des lymphocytes</term>
<term>Animaux</term>
<term>Antigènes d'helminthe (immunologie)</term>
<term>Brugia (immunologie)</term>
<term>Filariose lymphatique (immunologie)</term>
<term>Humains</term>
<term>Immunité cellulaire</term>
<term>Immunoglobuline G (biosynthèse)</term>
<term>Immunoglobuline M (biosynthèse)</term>
<term>Lymphocytes T régulateurs (immunologie)</term>
<term>Lymphoedème (immunologie)</term>
<term>Production d'anticorps</term>
<term>Tolérance immunitaire</term>
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<term>Immunoglobulin G</term>
<term>Immunoglobulin M</term>
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<term>Antigens, Helminth</term>
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<keywords scheme="MESH" qualifier="biosynthèse" xml:lang="fr">
<term>Immunoglobuline G</term>
<term>Immunoglobuline M</term>
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<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr">
<term>Antigènes d'helminthe</term>
<term>Brugia</term>
<term>Filariose lymphatique</term>
<term>Lymphocytes T régulateurs</term>
<term>Lymphoedème</term>
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<keywords scheme="MESH" qualifier="immunology" xml:lang="en">
<term>Brugia</term>
<term>Elephantiasis, Filarial</term>
<term>Lymphedema</term>
<term>T-Lymphocytes, Regulatory</term>
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<term>Activation des lymphocytes</term>
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<div type="abstract" xml:lang="en">The nature and intensity of immune reactions to filarial antigens appear to be controlled by two broad mechanisms: immunoregulation and immune tolerance. Parasite molecules of high molecular weight activate suppressor T lymphocytes; suppressive parasite products are present in sera from microfilaraemic patients. Prenatal or perinatal exposure to soluble parasite antigens may influence a person's future ability to react to filarial antigens.</div>
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