Regulation of immune responses in lymphatic filariasis.
Identifieur interne : 00E596 ( Main/Exploration ); précédent : 00E595; suivant : 00E597Regulation of immune responses in lymphatic filariasis.
Auteurs : W F Piessens ; A A Wadee ; L. KurniawanSource :
- Ciba Foundation symposium [ 0300-5208 ] ; 1987.
Descripteurs français
- KwdFr :
- Activation des lymphocytes, Animaux, Antigènes d'helminthe (immunologie), Brugia (immunologie), Filariose lymphatique (immunologie), Humains, Immunité cellulaire, Immunoglobuline G (biosynthèse), Immunoglobuline M (biosynthèse), Lymphocytes T régulateurs (immunologie), Lymphoedème (immunologie), Production d'anticorps, Tolérance immunitaire.
- MESH :
English descriptors
- KwdEn :
- Animals, Antibody Formation, Antigens, Helminth (immunology), Brugia (immunology), Elephantiasis, Filarial (immunology), Humans, Immune Tolerance, Immunity, Cellular, Immunoglobulin G (biosynthesis), Immunoglobulin M (biosynthesis), Lymphedema (immunology), Lymphocyte Activation, T-Lymphocytes, Regulatory (immunology).
- MESH :
- chemical , biosynthesis : Immunoglobulin G, Immunoglobulin M.
- chemical , immunology : Antigens, Helminth.
- immunology : Brugia, Elephantiasis, Filarial, Lymphedema, T-Lymphocytes, Regulatory.
- Animals, Antibody Formation, Humans, Immune Tolerance, Immunity, Cellular, Lymphocyte Activation.
Abstract
The nature and intensity of immune reactions to filarial antigens appear to be controlled by two broad mechanisms: immunoregulation and immune tolerance. Parasite molecules of high molecular weight activate suppressor T lymphocytes; suppressive parasite products are present in sera from microfilaraemic patients. Prenatal or perinatal exposure to soluble parasite antigens may influence a person's future ability to react to filarial antigens.
PubMed: 2954794
Affiliations:
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Le document en format XML
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<term>Antibody Formation</term>
<term>Antigens, Helminth (immunology)</term>
<term>Brugia (immunology)</term>
<term>Elephantiasis, Filarial (immunology)</term>
<term>Humans</term>
<term>Immune Tolerance</term>
<term>Immunity, Cellular</term>
<term>Immunoglobulin G (biosynthesis)</term>
<term>Immunoglobulin M (biosynthesis)</term>
<term>Lymphedema (immunology)</term>
<term>Lymphocyte Activation</term>
<term>T-Lymphocytes, Regulatory (immunology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Activation des lymphocytes</term>
<term>Animaux</term>
<term>Antigènes d'helminthe (immunologie)</term>
<term>Brugia (immunologie)</term>
<term>Filariose lymphatique (immunologie)</term>
<term>Humains</term>
<term>Immunité cellulaire</term>
<term>Immunoglobuline G (biosynthèse)</term>
<term>Immunoglobuline M (biosynthèse)</term>
<term>Lymphocytes T régulateurs (immunologie)</term>
<term>Lymphoedème (immunologie)</term>
<term>Production d'anticorps</term>
<term>Tolérance immunitaire</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>Immunoglobulin G</term>
<term>Immunoglobulin M</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antigens, Helminth</term>
</keywords>
<keywords scheme="MESH" qualifier="biosynthèse" xml:lang="fr"><term>Immunoglobuline G</term>
<term>Immunoglobuline M</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Antigènes d'helminthe</term>
<term>Brugia</term>
<term>Filariose lymphatique</term>
<term>Lymphocytes T régulateurs</term>
<term>Lymphoedème</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Brugia</term>
<term>Elephantiasis, Filarial</term>
<term>Lymphedema</term>
<term>T-Lymphocytes, Regulatory</term>
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<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Antibody Formation</term>
<term>Humans</term>
<term>Immune Tolerance</term>
<term>Immunity, Cellular</term>
<term>Lymphocyte Activation</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Activation des lymphocytes</term>
<term>Animaux</term>
<term>Humains</term>
<term>Immunité cellulaire</term>
<term>Production d'anticorps</term>
<term>Tolérance immunitaire</term>
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<front><div type="abstract" xml:lang="en">The nature and intensity of immune reactions to filarial antigens appear to be controlled by two broad mechanisms: immunoregulation and immune tolerance. Parasite molecules of high molecular weight activate suppressor T lymphocytes; suppressive parasite products are present in sera from microfilaraemic patients. Prenatal or perinatal exposure to soluble parasite antigens may influence a person's future ability to react to filarial antigens.</div>
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<affiliations><list></list>
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<name sortKey="Piessens, W F" sort="Piessens, W F" uniqKey="Piessens W" first="W F" last="Piessens">W F Piessens</name>
<name sortKey="Wadee, A A" sort="Wadee, A A" uniqKey="Wadee A" first="A A" last="Wadee">A A Wadee</name>
</noCountry>
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</record>
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