The role of macrophages on the expression of sex difference in the susceptibility to Brugia pahangi infection in C57BL/6 mice.
Identifieur interne : 00DE02 ( Main/Exploration ); précédent : 00DE01; suivant : 00DE03The role of macrophages on the expression of sex difference in the susceptibility to Brugia pahangi infection in C57BL/6 mice.
Auteurs : H. Nakanishi [Japon] ; Y. Horii ; K. FujitaSource :
- Journal of helminthology [ 0022-149X ] ; 1989.
Descripteurs français
- KwdFr :
- Animaux, Brugia (immunologie), Brugia (isolement et purification), Carbone (pharmacologie), Facteurs sexuels, Femelle, Filariose lymphatique (immunologie), Filarioses (immunologie), Granulocytes éosinophiles (), Granulocytes éosinophiles (immunologie), Macrophages (), Macrophages (immunologie), Mâle, Numération cellulaire, Prométhazine (pharmacologie), Souris, Souris de lignée C57BL, Susceptibilité à une maladie.
- MESH :
- immunologie : Brugia, Filariose lymphatique, Filarioses, Granulocytes éosinophiles, Macrophages.
- isolement et purification : Brugia.
- pharmacologie : Carbone, Prométhazine.
- Animaux, Facteurs sexuels, Femelle, Granulocytes éosinophiles, Macrophages, Mâle, Numération cellulaire, Souris, Souris de lignée C57BL, Susceptibilité à une maladie.
English descriptors
- KwdEn :
- Animals, Brugia (immunology), Brugia (isolation & purification), Carbon (pharmacology), Cell Count, Disease Susceptibility, Elephantiasis, Filarial (immunology), Eosinophils (drug effects), Eosinophils (immunology), Female, Filariasis (immunology), Macrophages (drug effects), Macrophages (immunology), Male, Mice, Mice, Inbred C57BL, Promethazine (pharmacology), Sex Factors.
- MESH :
- chemical , pharmacology : Carbon, Promethazine.
- drug effects : Eosinophils, Macrophages.
- immunology : Brugia, Elephantiasis, Filarial, Eosinophils, Filariasis, Macrophages.
- isolation & purification : Brugia.
- Animals, Cell Count, Disease Susceptibility, Female, Male, Mice, Mice, Inbred C57BL, Sex Factors.
Abstract
The role of macrophages or eosinophils on the expression of sex difference in the susceptibility to a primary Brugia pahangi infection in C57BL/6 mice was investigated by using a macrophage blockade technique (carbon treatment) or a histamine type 1 (H1) receptor antagonist (promethazine). Carbon treatment remarkably inhibited macrophage exudation, reduced the resistance of female mice, and completely abolished sex difference in the susceptibility to B. pahangi infection. Although promethazine treatment inhibited eosinophil exudation, it caused only a little increase (not significant) in the recovery rate of worms. These results suggest that macrophages have more important role(s) than do eosinophils on the expression of sex difference in the susceptibility to a primary B. pahangi infection in C57BL/6 mice.
PubMed: 2794454
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 005F39
- to stream PubMed, to step Curation: 005F39
- to stream PubMed, to step Checkpoint: 005F39
- to stream Ncbi, to step Merge: 008B00
- to stream Ncbi, to step Curation: 008B00
- to stream Ncbi, to step Checkpoint: 008B00
- to stream Main, to step Merge: 00EA21
- to stream Main, to step Curation: 00DE02
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The role of macrophages on the expression of sex difference in the susceptibility to Brugia pahangi infection in C57BL/6 mice.</title>
<author><name sortKey="Nakanishi, H" sort="Nakanishi, H" uniqKey="Nakanishi H" first="H" last="Nakanishi">H. Nakanishi</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Medical Zoology, Nagasaki University School of Medicine, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Medical Zoology, Nagasaki University School of Medicine</wicri:regionArea>
<wicri:noRegion>Nagasaki University School of Medicine</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Horii, Y" sort="Horii, Y" uniqKey="Horii Y" first="Y" last="Horii">Y. Horii</name>
</author>
<author><name sortKey="Fujita, K" sort="Fujita, K" uniqKey="Fujita K" first="K" last="Fujita">K. Fujita</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="1989">1989</date>
<idno type="RBID">pubmed:2794454</idno>
<idno type="pmid">2794454</idno>
<idno type="wicri:Area/PubMed/Corpus">005F39</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">005F39</idno>
<idno type="wicri:Area/PubMed/Curation">005F39</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">005F39</idno>
<idno type="wicri:Area/PubMed/Checkpoint">005F39</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">005F39</idno>
<idno type="wicri:Area/Ncbi/Merge">008B00</idno>
<idno type="wicri:Area/Ncbi/Curation">008B00</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">008B00</idno>
<idno type="wicri:doubleKey">0022-149X:1989:Nakanishi H:the:role:of</idno>
<idno type="wicri:Area/Main/Merge">00EA21</idno>
<idno type="wicri:Area/Main/Curation">00DE02</idno>
<idno type="wicri:Area/Main/Exploration">00DE02</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">The role of macrophages on the expression of sex difference in the susceptibility to Brugia pahangi infection in C57BL/6 mice.</title>
<author><name sortKey="Nakanishi, H" sort="Nakanishi, H" uniqKey="Nakanishi H" first="H" last="Nakanishi">H. Nakanishi</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Medical Zoology, Nagasaki University School of Medicine, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Medical Zoology, Nagasaki University School of Medicine</wicri:regionArea>
<wicri:noRegion>Nagasaki University School of Medicine</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Horii, Y" sort="Horii, Y" uniqKey="Horii Y" first="Y" last="Horii">Y. Horii</name>
</author>
<author><name sortKey="Fujita, K" sort="Fujita, K" uniqKey="Fujita K" first="K" last="Fujita">K. Fujita</name>
</author>
</analytic>
<series><title level="j">Journal of helminthology</title>
<idno type="ISSN">0022-149X</idno>
<imprint><date when="1989" type="published">1989</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Brugia (immunology)</term>
<term>Brugia (isolation & purification)</term>
<term>Carbon (pharmacology)</term>
<term>Cell Count</term>
<term>Disease Susceptibility</term>
<term>Elephantiasis, Filarial (immunology)</term>
<term>Eosinophils (drug effects)</term>
<term>Eosinophils (immunology)</term>
<term>Female</term>
<term>Filariasis (immunology)</term>
<term>Macrophages (drug effects)</term>
<term>Macrophages (immunology)</term>
<term>Male</term>
<term>Mice</term>
<term>Mice, Inbred C57BL</term>
<term>Promethazine (pharmacology)</term>
<term>Sex Factors</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Brugia (immunologie)</term>
<term>Brugia (isolement et purification)</term>
<term>Carbone (pharmacologie)</term>
<term>Facteurs sexuels</term>
<term>Femelle</term>
<term>Filariose lymphatique (immunologie)</term>
<term>Filarioses (immunologie)</term>
<term>Granulocytes éosinophiles ()</term>
<term>Granulocytes éosinophiles (immunologie)</term>
<term>Macrophages ()</term>
<term>Macrophages (immunologie)</term>
<term>Mâle</term>
<term>Numération cellulaire</term>
<term>Prométhazine (pharmacologie)</term>
<term>Souris</term>
<term>Souris de lignée C57BL</term>
<term>Susceptibilité à une maladie</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Carbon</term>
<term>Promethazine</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Eosinophils</term>
<term>Macrophages</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Brugia</term>
<term>Filariose lymphatique</term>
<term>Filarioses</term>
<term>Granulocytes éosinophiles</term>
<term>Macrophages</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Brugia</term>
<term>Elephantiasis, Filarial</term>
<term>Eosinophils</term>
<term>Filariasis</term>
<term>Macrophages</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Brugia</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Brugia</term>
</keywords>
<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Carbone</term>
<term>Prométhazine</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Cell Count</term>
<term>Disease Susceptibility</term>
<term>Female</term>
<term>Male</term>
<term>Mice</term>
<term>Mice, Inbred C57BL</term>
<term>Sex Factors</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Facteurs sexuels</term>
<term>Femelle</term>
<term>Granulocytes éosinophiles</term>
<term>Macrophages</term>
<term>Mâle</term>
<term>Numération cellulaire</term>
<term>Souris</term>
<term>Souris de lignée C57BL</term>
<term>Susceptibilité à une maladie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The role of macrophages or eosinophils on the expression of sex difference in the susceptibility to a primary Brugia pahangi infection in C57BL/6 mice was investigated by using a macrophage blockade technique (carbon treatment) or a histamine type 1 (H1) receptor antagonist (promethazine). Carbon treatment remarkably inhibited macrophage exudation, reduced the resistance of female mice, and completely abolished sex difference in the susceptibility to B. pahangi infection. Although promethazine treatment inhibited eosinophil exudation, it caused only a little increase (not significant) in the recovery rate of worms. These results suggest that macrophages have more important role(s) than do eosinophils on the expression of sex difference in the susceptibility to a primary B. pahangi infection in C57BL/6 mice.</div>
</front>
</TEI>
<affiliations><list><country><li>Japon</li>
</country>
</list>
<tree><noCountry><name sortKey="Fujita, K" sort="Fujita, K" uniqKey="Fujita K" first="K" last="Fujita">K. Fujita</name>
<name sortKey="Horii, Y" sort="Horii, Y" uniqKey="Horii Y" first="Y" last="Horii">Y. Horii</name>
</noCountry>
<country name="Japon"><noRegion><name sortKey="Nakanishi, H" sort="Nakanishi, H" uniqKey="Nakanishi H" first="H" last="Nakanishi">H. Nakanishi</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 00DE02 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 00DE02 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= Main |étape= Exploration |type= RBID |clé= pubmed:2794454 |texte= The role of macrophages on the expression of sex difference in the susceptibility to Brugia pahangi infection in C57BL/6 mice. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:2794454" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a LymphedemaV1
This area was generated with Dilib version V0.6.31. |