LymphedemaV1, Main, Exploration, bibRecord, 00DA69

Age-related changes of the susceptibility to infection with Brugia pahangi in male and female BALB/c mice.

Identifieur interne : 00DA69 ( Main/Exploration ); précédent : 00DA68; suivant : 00DA70

Age-related changes of the susceptibility to infection with Brugia pahangi in male and female BALB/c mice.

Auteurs : H. Nakanishi [Japon] ; Y. Horii ; K. Terashima ; K. Fujita

Source :

The Journal of parasitology [ 0022-3395 ] ; 1990.

RBID : pubmed:2319434

Descripteurs français

KwdFr :
- Animaux, Brugia, Facteurs sexuels, Femelle, Filariose lymphatique (immunologie), Filarioses (immunologie), Mâle, Souris, Souris de lignée BALB C, Susceptibilité à une maladie, Vieillissement (immunologie).
MESH :
- immunologie : Filariose lymphatique, Filarioses, Vieillissement.
- Animaux, Brugia, Facteurs sexuels, Femelle, Mâle, Souris, Souris de lignée BALB C, Susceptibilité à une maladie.

English descriptors

KwdEn :
- Aging (immunology), Animals, Brugia, Disease Susceptibility, Elephantiasis, Filarial (immunology), Female, Filariasis (immunology), Male, Mice, Mice, Inbred BALB C, Sex Factors.
MESH :
- immunology : Aging, Elephantiasis, Filarial, Filariasis.
- Animals, Brugia, Disease Susceptibility, Female, Male, Mice, Mice, Inbred BALB C, Sex Factors.

Abstract

Effects of host age and sex on murine Brugia pahangi infection were examined. In female BALB/c mice, partial resistance to B. pahangi developed rapidly with age. In animals inoculated at 5-6 wk of age, resistance was about 2 times higher than in the youngest group (2-3 wk) and remained at a similar level through the study period (12 wk). Male BALB/c mice showed a similar tendency until 5-6 wk of age, but afterward their susceptibility increased with age. Significant difference in the susceptibility was detected between sexes after sexual maturation. After macrophage blockade by an injection of carbon particles into the mice, the age- and sex-related differences were completely abolished. This suggests that macrophages might have an important role(s) in the age- and sex-related changes of susceptibility to B. pahangi in BALB/c mice.

PubMed: 2319434

Affiliations:

Japon

Le document en format XML

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<author><name sortKey="Terashima, K" sort="Terashima, K" uniqKey="Terashima K" first="K" last="Terashima">K. Terashima</name>
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<term>Mâle</term>
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<term>Vieillissement (immunologie)</term>
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<term>Filarioses</term>
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<front><div type="abstract" xml:lang="en">Effects of host age and sex on murine Brugia pahangi infection were examined. In female BALB/c mice, partial resistance to B. pahangi developed rapidly with age. In animals inoculated at 5-6 wk of age, resistance was about 2 times higher than in the youngest group (2-3 wk) and remained at a similar level through the study period (12 wk). Male BALB/c mice showed a similar tendency until 5-6 wk of age, but afterward their susceptibility increased with age. Significant difference in the susceptibility was detected between sexes after sexual maturation. After macrophage blockade by an injection of carbon particles into the mice, the age- and sex-related differences were completely abolished. This suggests that macrophages might have an important role(s) in the age- and sex-related changes of susceptibility to B. pahangi in BALB/c mice.</div>
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<name sortKey="Terashima, K" sort="Terashima, K" uniqKey="Terashima K" first="K" last="Terashima">K. Terashima</name>
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<country name="Japon"><noRegion><name sortKey="Nakanishi, H" sort="Nakanishi, H" uniqKey="Nakanishi H" first="H" last="Nakanishi">H. Nakanishi</name>
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Age-related changes of the susceptibility to infection with Brugia pahangi in male and female BALB/c mice.

Age-related changes of the susceptibility to infection with Brugia pahangi in male and female BALB/c mice.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
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