Diethylcarbamazine salt in the control of lymphatic filariasis.
Identifieur interne : 00C856 ( Main/Exploration ); précédent : 00C855; suivant : 00C857Diethylcarbamazine salt in the control of lymphatic filariasis.
Auteurs : H. GelbandSource :
- The American journal of tropical medicine and hygiene [ 0002-9637 ] ; 1994.
Descripteurs français
- KwdFr :
- MESH :
- traitement médicamenteux : Filariose lymphatique.
- usage thérapeutique : Diéthylcarbamazine.
- Animaux, Brugia malayi, Chine, Filariose lymphatique, Humains, Inde, Taïwan, Wuchereria bancrofti.
- Wicri :
- geographic : République populaire de Chine, Inde, Taïwan.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Diethylcarbamazine.
- geographic : China, India, Taiwan.
- drug therapy : Elephantiasis, Filarial.
- prevention & control : Elephantiasis, Filarial.
- Animals, Brugia malayi, Humans, Wuchereria bancrofti.
Abstract
Where lymphatic filariasis has diminished since about the 1950s, it has most frequently, though not always, been a direct result of chemotherapeutic intervention against the parasite. Diethylcarbamazine (DEC), a well-established drug, has been the single agent of chemotherapeutic control and has been successful in a wide variety of regimens. This paper reviews the experience with one strategy: long-term, low-dose treatment through DEC-medicated common salt. Diethylcarbamazine-medicated salt played a major role in the Chinese filariasis control program and has been successful in more limited trials in India, Brazil, and Tanzania. It is not being used today in any endemic area, but the evidence suggests that it is safe, effective, and relatively inexpensive. Enough is already known about the beneficial effects of DEC-medicated salt from community-wide studies to develop specific guidelines for its use in community programs.
PubMed: 8024057
Affiliations:
Links toward previous steps (curation, corpus...)
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Le document en format XML
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Brugia malayi</term>
<term>China</term>
<term>Diethylcarbamazine (therapeutic use)</term>
<term>Elephantiasis, Filarial (drug therapy)</term>
<term>Elephantiasis, Filarial (prevention & control)</term>
<term>Humans</term>
<term>India</term>
<term>Taiwan</term>
<term>Wuchereria bancrofti</term>
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<term>Brugia malayi</term>
<term>Chine</term>
<term>Diéthylcarbamazine (usage thérapeutique)</term>
<term>Filariose lymphatique ()</term>
<term>Filariose lymphatique (traitement médicamenteux)</term>
<term>Humains</term>
<term>Inde</term>
<term>Taïwan</term>
<term>Wuchereria bancrofti</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Diethylcarbamazine</term>
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<term>India</term>
<term>Taiwan</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Elephantiasis, Filarial</term>
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<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Filariose lymphatique</term>
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<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Diéthylcarbamazine</term>
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<term>Brugia malayi</term>
<term>Humans</term>
<term>Wuchereria bancrofti</term>
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<term>Brugia malayi</term>
<term>Chine</term>
<term>Filariose lymphatique</term>
<term>Humains</term>
<term>Inde</term>
<term>Taïwan</term>
<term>Wuchereria bancrofti</term>
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<front><div type="abstract" xml:lang="en">Where lymphatic filariasis has diminished since about the 1950s, it has most frequently, though not always, been a direct result of chemotherapeutic intervention against the parasite. Diethylcarbamazine (DEC), a well-established drug, has been the single agent of chemotherapeutic control and has been successful in a wide variety of regimens. This paper reviews the experience with one strategy: long-term, low-dose treatment through DEC-medicated common salt. Diethylcarbamazine-medicated salt played a major role in the Chinese filariasis control program and has been successful in more limited trials in India, Brazil, and Tanzania. It is not being used today in any endemic area, but the evidence suggests that it is safe, effective, and relatively inexpensive. Enough is already known about the beneficial effects of DEC-medicated salt from community-wide studies to develop specific guidelines for its use in community programs.</div>
</front>
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<tree><noCountry><name sortKey="Gelband, H" sort="Gelband, H" uniqKey="Gelband H" first="H" last="Gelband">H. Gelband</name>
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