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[Kaposi sarcoma in cyclosporin A therapy of actinic reticuloid].

Identifieur interne : 00B717 ( Main/Exploration ); précédent : 00B716; suivant : 00B718

[Kaposi sarcoma in cyclosporin A therapy of actinic reticuloid].

Auteurs : V. Waldmann ; W. Kempf ; G. Burg ; R. Dummer

Source :

RBID : pubmed:9206716

Descripteurs français

English descriptors

Abstract

A 76 year old patient with actinic reticuloid was treated with Cyclosporin A. 11 months after beginning the immunosuppressive therapy, he developed lymphoedema and livid nodular skin lesions of the right leg, which histologically showed Kaposi's sarcoma. After stopping the Cyclosporin A and intralesional therapy with Interferon alpha, no regression of the Kaposi sarcoma could be seen. The characteristics of Kaposi sarcoma arising during immunosuppressive therapy and the differences in incidence, risk groups and distribution pattern compared to the classic sporadic and the AIDS-related Kaposi sarcoma will be described. The development of Kaposi sarcoma during immunosuppressive therapy for actinic reticuloid has not been previously described.

PubMed: 9206716


Affiliations:


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Le document en format XML

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<term>Cyclosporine (adverse effects)</term>
<term>Cyclosporine (therapeutic use)</term>
<term>Humans</term>
<term>Immunosuppressive Agents (adverse effects)</term>
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<term>Sarcoma, Kaposi (chemically induced)</term>
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<term>Ciclosporine (effets indésirables)</term>
<term>Ciclosporine (usage thérapeutique)</term>
<term>Facteurs de risque</term>
<term>Humains</term>
<term>Immunosuppresseurs (effets indésirables)</term>
<term>Immunosuppresseurs (usage thérapeutique)</term>
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<term>Peau (anatomopathologie)</term>
<term>Photodermatoses (anatomopathologie)</term>
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<term>Sarcome de Kaposi ()</term>
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<div type="abstract" xml:lang="en">A 76 year old patient with actinic reticuloid was treated with Cyclosporin A. 11 months after beginning the immunosuppressive therapy, he developed lymphoedema and livid nodular skin lesions of the right leg, which histologically showed Kaposi's sarcoma. After stopping the Cyclosporin A and intralesional therapy with Interferon alpha, no regression of the Kaposi sarcoma could be seen. The characteristics of Kaposi sarcoma arising during immunosuppressive therapy and the differences in incidence, risk groups and distribution pattern compared to the classic sporadic and the AIDS-related Kaposi sarcoma will be described. The development of Kaposi sarcoma during immunosuppressive therapy for actinic reticuloid has not been previously described.</div>
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