Lessons Learned from the Initial 100 Patient Experience with Sentinel Lymph Node Mapping in the Evaluation of Breast Cancer
Identifieur interne : 00A231 ( Main/Exploration ); précédent : 00A230; suivant : 00A232Lessons Learned from the Initial 100 Patient Experience with Sentinel Lymph Node Mapping in the Evaluation of Breast Cancer
Auteurs : George M. Fuhrman ; Ernest G. Burch ; Gist H. Farr ; Tari A. King ; Emily Farkas ; John S. BoltonSource :
- The Ochsner Journal [ 1524-5012 ] ; 2000.
Abstract
The initial reports of sentinel lymph node mapping for breast cancer currently appearing in the surgical literature are demonstrating the practicality and accuracy of the technique to evaluate patients for axillary nodal disease. We reviewed our initial 100 patient experience with sentinel node mapping to evaluate our ability to employ this technique in breast cancer patients. We combined a peritumoral injection of a radioactive substance and blue dye. Each sentinel node was evaluated with frozen section analysis, hematoxylin and eosin staining, and, if still negative, five re-cuts were taken from deeper levels of the node and evaluated for immunohistochemical evidence of cytokeratin staining. Sentinel node(s) were identified in all but two patients with 51% demonstrating metastasis. We have demonstrated the ability to accurately perform sentinel node mapping in the evaluation of our breast cancer patients. This exciting advance should become a standard part of breast cancer surgery.
Url:
PubMed: 21765657
PubMed Central: 3117549
Affiliations:
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Fuhrman</name></author><author><name sortKey="Burch, Ernest G" sort="Burch, Ernest G" uniqKey="Burch E" first="Ernest G." last="Burch">Ernest G. Burch</name></author><author><name sortKey="Farr, Gist H" sort="Farr, Gist H" uniqKey="Farr G" first="Gist H." last="Farr">Gist H. Farr</name></author><author><name sortKey="King, Tari A" sort="King, Tari A" uniqKey="King T" first="Tari A." last="King">Tari A. King</name></author><author><name sortKey="Farkas, Emily" sort="Farkas, Emily" uniqKey="Farkas E" first="Emily" last="Farkas">Emily Farkas</name></author><author><name sortKey="Bolton, John S" sort="Bolton, John S" uniqKey="Bolton J" first="John S." last="Bolton">John S. Bolton</name></author></analytic><series><title level="j">The Ochsner Journal</title><idno type="ISSN">1524-5012</idno><imprint><date when="2000">2000</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The initial reports of sentinel lymph node mapping for breast cancer currently appearing in the surgical literature are demonstrating the practicality and accuracy of the technique to evaluate patients for axillary nodal disease. We reviewed our initial 100 patient experience with sentinel node mapping to evaluate our ability to employ this technique in breast cancer patients. We combined a peritumoral injection of a radioactive substance and blue dye. Each sentinel node was evaluated with frozen section analysis, hematoxylin and eosin staining, and, if still negative, five re-cuts were taken from deeper levels of the node and evaluated for immunohistochemical evidence of cytokeratin staining. Sentinel node(s) were identified in all but two patients with 51% demonstrating metastasis. We have demonstrated the ability to accurately perform sentinel node mapping in the evaluation of our breast cancer patients. This exciting advance should become a standard part of breast cancer surgery.</p></div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Bolton, John S" sort="Bolton, John S" uniqKey="Bolton J" first="John S." last="Bolton">John S. Bolton</name><name sortKey="Burch, Ernest G" sort="Burch, Ernest G" uniqKey="Burch E" first="Ernest G." last="Burch">Ernest G. Burch</name><name sortKey="Farkas, Emily" sort="Farkas, Emily" uniqKey="Farkas E" first="Emily" last="Farkas">Emily Farkas</name><name sortKey="Farr, Gist H" sort="Farr, Gist H" uniqKey="Farr G" first="Gist H." last="Farr">Gist H. Farr</name><name sortKey="Fuhrman, George M" sort="Fuhrman, George M" uniqKey="Fuhrman G" first="George M." last="Fuhrman">George M. Fuhrman</name><name sortKey="King, Tari A" sort="King, Tari A" uniqKey="King T" first="Tari A." last="King">Tari A. King</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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