Graves' disease presenting as elephantiasic pretibial myxedema and nodules of the hands
Identifieur interne : 009F15 ( Main/Exploration ); précédent : 009F14; suivant : 009F16Graves' disease presenting as elephantiasic pretibial myxedema and nodules of the hands
Auteurs : Soyun Cho [Corée du Sud] ; Jee-Ho Choi [Corée du Sud] ; Kyung-Jeh Sung [Corée du Sud] ; Kee-Chan Moon [Corée du Sud] ; Jai-Kyoung Koh [Corée du Sud]Source :
- International Journal of Dermatology [ 0011-9059 ] ; 2001-04.
Abstract
A 67‐year‐old man presented with a 2‐year history of asymptomatic, firm, multiple nodules and plaques and cerebriform hypertrophy of both lower legs and feet, and well‐defined, skin‐colored, firm nodules and tumors on both hands. He had been diagnosed as having Graves' disease 3 years previously, and had been treated with 10 mg of methimazole and 100 μg of thyroxin (T4) daily for 2 years. Physical examination revealed nonpitting edema, flesh‐colored to erythematous, firm, confluent, polypoid nodules and fissured plaques extending from the shins to the dorsa of both feet (Fig. 1), and round to oval, firm, skin‐colored, walnut‐to‐egg‐sized tumors on all 10 fingers and the ulnar side of the dorsum of the right hand (Fig. 2). The thyroid gland was diffusely enlarged; however, there was no exophthalmos, and extraocular movements were normal. There was no weight loss, loss of appetite, tremor, heat intolerance, diarrhea, or fatigue. On laboratory evaluation, thyroid‐stimulating hormone (TSH) had a markedly low titer of < 0.05 μU/mL (normal: 0.4–5.0), and the TSH receptor antibody was extremely high at 73.8% (normal: < 15%). Serum free triiodothyronine (T3), T4, antimicrosome, and antithyroglobulin antibodies were normal or negative. Skin biopsy samples from the shin and hand disclosed extensive mucin deposition throughout the dermis. Confluent, firm nodules and plaques on both shins and the dorsa of both feet Firm, nonpitting, well‐circumscribed, flesh‐colored masses with orange‐peel appearance of overlying skin and growth of coarse hair on the dorsum of the right hand
Url:
DOI: 10.1046/j.1365-4362.2001.01108.x
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000D35
- to stream Istex, to step Curation: 000D35
- to stream Istex, to step Checkpoint: 002C19
- to stream Main, to step Merge: 00A369
- to stream Main, to step Curation: 009F15
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Graves' disease presenting as elephantiasic pretibial myxedema and nodules of the hands</title><author><name sortKey="Cho, Soyun" sort="Cho, Soyun" uniqKey="Cho S" first="Soyun" last="Cho">Soyun Cho</name></author><author><name sortKey="Choi, Jee O" sort="Choi, Jee O" uniqKey="Choi J" first="Jee-Ho" last="Choi">Jee-Ho Choi</name></author><author><name sortKey="Sung, Kyung Eh" sort="Sung, Kyung Eh" uniqKey="Sung K" first="Kyung-Jeh" last="Sung">Kyung-Jeh Sung</name></author><author><name sortKey="Moon, Kee Han" sort="Moon, Kee Han" uniqKey="Moon K" first="Kee-Chan" last="Moon">Kee-Chan Moon</name></author><author><name sortKey="Koh, Jai Young" sort="Koh, Jai Young" uniqKey="Koh J" first="Jai-Kyoung" last="Koh">Jai-Kyoung Koh</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:1C8DF41186D35F4A81936D55476A4FCC579F99B8</idno><date when="2001" year="2001">2001</date><idno type="doi">10.1046/j.1365-4362.2001.01108.x</idno><idno type="url">https://api.istex.fr/document/1C8DF41186D35F4A81936D55476A4FCC579F99B8/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000D35</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000D35</idno><idno type="wicri:Area/Istex/Curation">000D35</idno><idno type="wicri:Area/Istex/Checkpoint">002C19</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">002C19</idno><idno type="wicri:doubleKey">0011-9059:2001:Cho S:graves:disease:presenting</idno><idno type="wicri:Area/Main/Merge">00A369</idno><idno type="wicri:Area/Main/Curation">009F15</idno><idno type="wicri:Area/Main/Exploration">009F15</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Graves' disease presenting as elephantiasic pretibial myxedema and nodules of the hands</title><author><name sortKey="Cho, Soyun" sort="Cho, Soyun" uniqKey="Cho S" first="Soyun" last="Cho">Soyun Cho</name><affiliation wicri:level="3"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Choi, Jee O" sort="Choi, Jee O" uniqKey="Choi J" first="Jee-Ho" last="Choi">Jee-Ho Choi</name><affiliation wicri:level="3"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Sung, Kyung Eh" sort="Sung, Kyung Eh" uniqKey="Sung K" first="Kyung-Jeh" last="Sung">Kyung-Jeh Sung</name><affiliation wicri:level="3"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Moon, Kee Han" sort="Moon, Kee Han" uniqKey="Moon K" first="Kee-Chan" last="Moon">Kee-Chan Moon</name><affiliation wicri:level="3"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Koh, Jai Young" sort="Koh, Jai Young" uniqKey="Koh J" first="Jai-Kyoung" last="Koh">Jai-Kyoung Koh</name><affiliation wicri:level="3"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">International Journal of Dermatology</title><title level="j" type="alt">INTERNATIONAL JOURNAL OF DERMATOLOGY</title><idno type="ISSN">0011-9059</idno><idno type="eISSN">1365-4632</idno><imprint><biblScope unit="vol">40</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="276">276</biblScope><biblScope unit="page" to="277">277</biblScope><biblScope unit="page-count">2</biblScope><publisher>Blackwell Science Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2001-04">2001-04</date></imprint><idno type="ISSN">0011-9059</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0011-9059</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A 67‐year‐old man presented with a 2‐year history of asymptomatic, firm, multiple nodules and plaques and cerebriform hypertrophy of both lower legs and feet, and well‐defined, skin‐colored, firm nodules and tumors on both hands. He had been diagnosed as having Graves' disease 3 years previously, and had been treated with 10 mg of methimazole and 100 μg of thyroxin (T4) daily for 2 years. Physical examination revealed nonpitting edema, flesh‐colored to erythematous, firm, confluent, polypoid nodules and fissured plaques extending from the shins to the dorsa of both feet (Fig. 1), and round to oval, firm, skin‐colored, walnut‐to‐egg‐sized tumors on all 10 fingers and the ulnar side of the dorsum of the right hand (Fig. 2). The thyroid gland was diffusely enlarged; however, there was no exophthalmos, and extraocular movements were normal. There was no weight loss, loss of appetite, tremor, heat intolerance, diarrhea, or fatigue. On laboratory evaluation, thyroid‐stimulating hormone (TSH) had a markedly low titer of < 0.05 μU/mL (normal: 0.4–5.0), and the TSH receptor antibody was extremely high at 73.8% (normal: < 15%). Serum free triiodothyronine (T3), T4, antimicrosome, and antithyroglobulin antibodies were normal or negative. Skin biopsy samples from the shin and hand disclosed extensive mucin deposition throughout the dermis. Confluent, firm nodules and plaques on both shins and the dorsa of both feet Firm, nonpitting, well‐circumscribed, flesh‐colored masses with orange‐peel appearance of overlying skin and growth of coarse hair on the dorsum of the right hand</div></front></TEI><affiliations><list><country><li>Corée du Sud</li></country><region><li>Région capitale de Séoul</li></region><settlement><li>Séoul</li></settlement></list><tree><country name="Corée du Sud"><region name="Région capitale de Séoul"><name sortKey="Cho, Soyun" sort="Cho, Soyun" uniqKey="Cho S" first="Soyun" last="Cho">Soyun Cho</name></region><name sortKey="Choi, Jee O" sort="Choi, Jee O" uniqKey="Choi J" first="Jee-Ho" last="Choi">Jee-Ho Choi</name><name sortKey="Koh, Jai Young" sort="Koh, Jai Young" uniqKey="Koh J" first="Jai-Kyoung" last="Koh">Jai-Kyoung Koh</name><name sortKey="Moon, Kee Han" sort="Moon, Kee Han" uniqKey="Moon K" first="Kee-Chan" last="Moon">Kee-Chan Moon</name><name sortKey="Sung, Kyung Eh" sort="Sung, Kyung Eh" uniqKey="Sung K" first="Kyung-Jeh" last="Sung">Kyung-Jeh Sung</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 009F15 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 009F15 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:1C8DF41186D35F4A81936D55476A4FCC579F99B8
|texte= Graves' disease presenting as elephantiasic pretibial myxedema and nodules of the hands
}}
| This area was generated with Dilib version V0.6.31. |  |