Lymphangiogenesis, myeloid cells and inflammation.
Identifieur interne : 006A50 ( Main/Exploration ); précédent : 006A49; suivant : 006A51Lymphangiogenesis, myeloid cells and inflammation.
Auteurs : Lianping Xing [États-Unis] ; Rui-Cheng JiSource :
- Expert review of clinical immunology [ 1744-8409 ] ; 2008.
Abstract
The lymphatic system is essential for the maintenance of tissue fluid balance, immune surveillance and the absorption of fatty acids in the gastrointestinal tract. The lymphatic circulation is also a key player in disease processes such as cancer metastasis, lymphedema and various inflammatory disorders. With the identification of specific growth factors for lymphatic endothelial cells and markers that distinguish blood and lymphatic vessels, as well as the development of in vivo imaging technologies that provide new tools to examine the lymphatic drainage function in real time, many advancements have been made in lymphatic vascular research during the past few years. Despite these significant achievements, our understanding of the role of lymphatics in disease processes other than cancer metastasis is still rather limited. The current review will focus on the recent progress made in studies of lymphatics in inflammatory disorders.
DOI: 10.1586/1744666X.4.5.599
PubMed: 20476963
Affiliations:
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