LymphedemaV1, Main, Exploration, bibRecord, 005F68

Topics of physiological and pathophysiological functions of lymphatics.

Identifieur interne : 005F68 ( Main/Exploration ); précédent : 005F67; suivant : 005F69

Topics of physiological and pathophysiological functions of lymphatics.

Auteurs : Y. Kawai [Japon] ; T. Ohhashi

Source :

Current molecular medicine [ 1875-5666 ] ; 2009.

RBID : pubmed:19925407

Descripteurs français

KwdFr :
- Animaux, Humains, Métastase lymphatique, Noeuds lymphatiques (physiologie), Système lymphatique (physiologie), Système lymphatique (physiopathologie), Tumeurs (physiopathologie).
MESH :
- physiologie : Noeuds lymphatiques, Système lymphatique.
- physiopathologie : Système lymphatique, Tumeurs.
- Animaux, Humains, Métastase lymphatique.

English descriptors

KwdEn :
- Animals, Humans, Lymph Nodes (physiology), Lymphatic Metastasis, Lymphatic System (physiology), Lymphatic System (physiopathology), Neoplasms (physiopathology).
MESH :
- physiology : Lymph Nodes, Lymphatic System.
- physiopathology : Lymphatic System, Neoplasms.
- Animals, Humans, Lymphatic Metastasis.

Abstract

We have reviewed physiological significance of rhythmical spontaneous contractions of collecting lymphatics, which play an important role in lymph transport and seem to regulate lymph formation through changing the pacemaker sites of the rhythmic contractions and conractile patterns of lymphangions. Next, we reported experimental findings that the wall effective permeability of hydrophilic substances labelled with fluorescent dyes was evaluated in an isolated cannulated rat single lymphatic using a microscope system. With the experimental evidence, we have discussed physiological significance and crucial roles of the enrichment of albumin in lymph through the wall of small lymphatics in regulation of innate immunity. In addition, we have described the mode of action of recanalization of collecting lymphatics after excision of lymph node with special reference to clinical treatment for surgical removal of lymph nodes-mediated secondary lymphedema. Finally, we have addressed the possibility that primary tumor cells and/or metastatic carcinoma cells themselves release key chemical substances to develop environment suitable for micro-metastasis in sentinel lymph node.

PubMed: 19925407

Affiliations:

Japon

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<term>Lymphatic System (physiopathology)</term>
<term>Neoplasms (physiopathology)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
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<term>Lymphatic System</term>
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<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Système lymphatique</term>
<term>Tumeurs</term>
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<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Lymphatic System</term>
<term>Neoplasms</term>
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<term>Humans</term>
<term>Lymphatic Metastasis</term>
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<term>Humains</term>
<term>Métastase lymphatique</term>
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<front><div type="abstract" xml:lang="en">We have reviewed physiological significance of rhythmical spontaneous contractions of collecting lymphatics, which play an important role in lymph transport and seem to regulate lymph formation through changing the pacemaker sites of the rhythmic contractions and conractile patterns of lymphangions. Next, we reported experimental findings that the wall effective permeability of hydrophilic substances labelled with fluorescent dyes was evaluated in an isolated cannulated rat single lymphatic using a microscope system. With the experimental evidence, we have discussed physiological significance and crucial roles of the enrichment of albumin in lymph through the wall of small lymphatics in regulation of innate immunity. In addition, we have described the mode of action of recanalization of collecting lymphatics after excision of lymph node with special reference to clinical treatment for surgical removal of lymph nodes-mediated secondary lymphedema. Finally, we have addressed the possibility that primary tumor cells and/or metastatic carcinoma cells themselves release key chemical substances to develop environment suitable for micro-metastasis in sentinel lymph node.</div>
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Topics of physiological and pathophysiological functions of lymphatics.

Topics of physiological and pathophysiological functions of lymphatics.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
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