Dermal mucinosis as a sign of venous insufficiency
Identifieur interne : 005D48 ( Main/Exploration ); précédent : 005D47; suivant : 005D49Dermal mucinosis as a sign of venous insufficiency
Auteurs : Rupa Pugashetti [États-Unis] ; Daniel C. Zedek [États-Unis] ; Elizabeth V. Seiverling [États-Unis] ; Priya Rajendran [États-Unis] ; Timothy Berger [États-Unis]Source :
- Journal of Cutaneous Pathology [ 0303-6987 ] ; 2010-02.
Abstract
Dermal mucinoses are a heterogeneous group of disorders characterized by abnormal deposition of dermal mucin, an amorphous substance composed of hyaluronic acid and sulfated glycosaminoglycans. We describe two cases of dermal mucinosis in the setting of chronic venous insufficiency. Both patients presented with painful, edematous lower extremity plaques. Biopsies of all lesions showed striking dermal mucin deposition, a slight increase in small blood vessel density, slightly thickened vessel walls and no inflammation. Neither patient showed laboratory or clinical findings consistent with a secondary mucinosis such as thyroid dysfunction, lupus erythematosus, dermatomyositis, scleroderma, granuloma annulare, graft‐vs.‐host disease or mucin deposition post‐ultraviolet or photochemotherapy treatment. Both patients were diagnosed with localized cutaneous mucinosis secondary to venous insufficiency. The clinicopathological features of this entity are described, and a pathogenic mechanism is proposed. Pugashetti R, Zedek DC, Seiverling EV, Rajendran P. Berger T. Dermal mucinosis as a sign of venous insufficiency.
Url:
DOI: 10.1111/j.1600-0560.2009.01306.x
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 004C95
- to stream Istex, to step Curation: 004C95
- to stream Istex, to step Checkpoint: 000A92
- to stream Main, to step Merge: 005E03
- to stream Main, to step Curation: 005D48
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Dermal mucinosis as a sign of venous insufficiency</title><author><name sortKey="Pugashetti, Rupa" sort="Pugashetti, Rupa" uniqKey="Pugashetti R" first="Rupa" last="Pugashetti">Rupa Pugashetti</name></author><author><name sortKey="Zedek, Daniel C" sort="Zedek, Daniel C" uniqKey="Zedek D" first="Daniel C." last="Zedek">Daniel C. Zedek</name></author><author><name sortKey="Seiverling, Elizabeth V" sort="Seiverling, Elizabeth V" uniqKey="Seiverling E" first="Elizabeth V." last="Seiverling">Elizabeth V. Seiverling</name></author><author><name sortKey="Rajendran, Priya" sort="Rajendran, Priya" uniqKey="Rajendran P" first="Priya" last="Rajendran">Priya Rajendran</name></author><author><name sortKey="Berger, Timothy" sort="Berger, Timothy" uniqKey="Berger T" first="Timothy" last="Berger">Timothy Berger</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:A3C4A50996FB103F3D3D15F01C381708CCB1FCBE</idno><date when="2010" year="2010">2010</date><idno type="doi">10.1111/j.1600-0560.2009.01306.x</idno><idno type="url">https://api.istex.fr/document/A3C4A50996FB103F3D3D15F01C381708CCB1FCBE/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">004C95</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">004C95</idno><idno type="wicri:Area/Istex/Curation">004C95</idno><idno type="wicri:Area/Istex/Checkpoint">000A92</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000A92</idno><idno type="wicri:doubleKey">0303-6987:2010:Pugashetti R:dermal:mucinosis:as</idno><idno type="wicri:Area/Main/Merge">005E03</idno><idno type="wicri:Area/Main/Curation">005D48</idno><idno type="wicri:Area/Main/Exploration">005D48</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Dermal mucinosis as a sign of venous insufficiency</title><author><name sortKey="Pugashetti, Rupa" sort="Pugashetti, Rupa" uniqKey="Pugashetti R" first="Rupa" last="Pugashetti">Rupa Pugashetti</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, University of California, San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Zedek, Daniel C" sort="Zedek, Daniel C" uniqKey="Zedek D" first="Daniel C." last="Zedek">Daniel C. Zedek</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, University of California, San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, University of California, San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation></affiliation></author><author><name sortKey="Seiverling, Elizabeth V" sort="Seiverling, Elizabeth V" uniqKey="Seiverling E" first="Elizabeth V." last="Seiverling">Elizabeth V. Seiverling</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, University of California, San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Rajendran, Priya" sort="Rajendran, Priya" uniqKey="Rajendran P" first="Priya" last="Rajendran">Priya Rajendran</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, University of California, San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Berger, Timothy" sort="Berger, Timothy" uniqKey="Berger T" first="Timothy" last="Berger">Timothy Berger</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, University of California, San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Cutaneous Pathology</title><title level="j" type="alt">JOURNAL OF CUTANEOUS PATHOLOGY</title><idno type="ISSN">0303-6987</idno><idno type="eISSN">1600-0560</idno><imprint><biblScope unit="vol">37</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="292">292</biblScope><biblScope unit="page" to="296">296</biblScope><biblScope unit="page-count">5</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2010-02">2010-02</date></imprint><idno type="ISSN">0303-6987</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0303-6987</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Dermal mucinoses are a heterogeneous group of disorders characterized by abnormal deposition of dermal mucin, an amorphous substance composed of hyaluronic acid and sulfated glycosaminoglycans. We describe two cases of dermal mucinosis in the setting of chronic venous insufficiency. Both patients presented with painful, edematous lower extremity plaques. Biopsies of all lesions showed striking dermal mucin deposition, a slight increase in small blood vessel density, slightly thickened vessel walls and no inflammation. Neither patient showed laboratory or clinical findings consistent with a secondary mucinosis such as thyroid dysfunction, lupus erythematosus, dermatomyositis, scleroderma, granuloma annulare, graft‐vs.‐host disease or mucin deposition post‐ultraviolet or photochemotherapy treatment. Both patients were diagnosed with localized cutaneous mucinosis secondary to venous insufficiency. The clinicopathological features of this entity are described, and a pathogenic mechanism is proposed. Pugashetti R, Zedek DC, Seiverling EV, Rajendran P. Berger T. Dermal mucinosis as a sign of venous insufficiency.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li></region></list><tree><country name="États-Unis"><region name="Californie"><name sortKey="Pugashetti, Rupa" sort="Pugashetti, Rupa" uniqKey="Pugashetti R" first="Rupa" last="Pugashetti">Rupa Pugashetti</name></region><name sortKey="Berger, Timothy" sort="Berger, Timothy" uniqKey="Berger T" first="Timothy" last="Berger">Timothy Berger</name><name sortKey="Rajendran, Priya" sort="Rajendran, Priya" uniqKey="Rajendran P" first="Priya" last="Rajendran">Priya Rajendran</name><name sortKey="Seiverling, Elizabeth V" sort="Seiverling, Elizabeth V" uniqKey="Seiverling E" first="Elizabeth V." last="Seiverling">Elizabeth V. Seiverling</name><name sortKey="Zedek, Daniel C" sort="Zedek, Daniel C" uniqKey="Zedek D" first="Daniel C." last="Zedek">Daniel C. Zedek</name><name sortKey="Zedek, Daniel C" sort="Zedek, Daniel C" uniqKey="Zedek D" first="Daniel C." last="Zedek">Daniel C. Zedek</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005D48 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 005D48 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:A3C4A50996FB103F3D3D15F01C381708CCB1FCBE
|texte= Dermal mucinosis as a sign of venous insufficiency
}}
| This area was generated with Dilib version V0.6.31. |  |