LymphedemaV1, Main, Exploration, bibRecord, 004297

Five-year follow-up of treatment outcomes in patients with early-stage breast cancer and clinically negative axillary nodes treated with no lymph node dissection or axillary clearance

Identifieur interne : 004297 ( Main/Exploration ); précédent : 004296; suivant : 004298

Five-year follow-up of treatment outcomes in patients with early-stage breast cancer and clinically negative axillary nodes treated with no lymph node dissection or axillary clearance

Auteurs : Daigo Yamamoto [Japon] ; Kanji Tanaka [Japon] ; Yu Tsubota [Japon] ; Noriko Sueoka [Japon] ; Tetsuji Shoji [Japon] ; Kayoko Kuwana [Japon] ; A-Hon Kwon [Japon]

Source :

Breast Cancer : Targets and Therapy [ 1179-1314 ] ; 2012.

RBID : PMC:3846707

Abstract

Background

Sentinel lymph node biopsy has steadily replaced axillary lymph node dissection (ALND) for staging clinically node-negative breast cancer. However, ALND remains standard management of the axilla when a tumor-positive sentinel lymph node is identified.

Methods

We identified 460 patients with breast cancer (clinically T1/T2N0M0) from the database for 1999–2004. Patient age ranged from 26 to 81 (median 50) years. Patients who underwent mastectomy or breast-conserving surgery with or without ALND were compared for regional recurrence, disease-free survival, and overall survival.

Results

Patients with ALND (n = 308) were compared with the no ALND group (n = 152). Five-year overall survival and disease-free survival were not significantly different between the two groups, while there was a significant difference between them for regional recurrence. Of the 152 patients who did not undergo axillary dissection, four developed ipsilateral axillary disease, most of whom were rescued by delayed axillary dissection. Further, the criterion for identifying lymphedema was used, ie, a 2 cm circumferential change at any measured location. As a result, the incidence of lymphedema in the ALND group was 12.7%, while it was not seen in the non ALND group.

Conclusion

There is a possibility that ALND may be omitted for cT1/T2N0M0 breast cancer through a combination of hormone therapy and adjuvant chemotherapy.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846707

DOI: 10.2147/BCTT.S36054
PubMed: 24367200
PubMed Central: 3846707

Affiliations:

Japon

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Five-year follow-up of treatment outcomes in patients with early-stage breast cancer and clinically negative axillary nodes treated with no lymph node dissection or axillary clearance</title>
<author><name sortKey="Yamamoto, Daigo" sort="Yamamoto, Daigo" uniqKey="Yamamoto D" first="Daigo" last="Yamamoto">Daigo Yamamoto</name>
<affiliation wicri:level="1"><nlm:aff id="af1-bctt-4-125">Department of Surgery, Kansai Medical University, Hirakata, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Surgery, Kansai Medical University, Hirakata</wicri:regionArea>
<wicri:noRegion>Hirakata</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tanaka, Kanji" sort="Tanaka, Kanji" uniqKey="Tanaka K" first="Kanji" last="Tanaka">Kanji Tanaka</name>
<affiliation wicri:level="1"><nlm:aff id="af2-bctt-4-125">Ribon-Rose Tanaka Kanji Breast Clinic, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Ribon-Rose Tanaka Kanji Breast Clinic</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tsubota, Yu" sort="Tsubota, Yu" uniqKey="Tsubota Y" first="Yu" last="Tsubota">Yu Tsubota</name>
<affiliation wicri:level="1"><nlm:aff id="af1-bctt-4-125">Department of Surgery, Kansai Medical University, Hirakata, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Surgery, Kansai Medical University, Hirakata</wicri:regionArea>
<wicri:noRegion>Hirakata</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sueoka, Noriko" sort="Sueoka, Noriko" uniqKey="Sueoka N" first="Noriko" last="Sueoka">Noriko Sueoka</name>
<affiliation wicri:level="1"><nlm:aff id="af1-bctt-4-125">Department of Surgery, Kansai Medical University, Hirakata, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Surgery, Kansai Medical University, Hirakata</wicri:regionArea>
<wicri:noRegion>Hirakata</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shoji, Tetsuji" sort="Shoji, Tetsuji" uniqKey="Shoji T" first="Tetsuji" last="Shoji">Tetsuji Shoji</name>
<affiliation wicri:level="1"><nlm:aff id="af3-bctt-4-125">Shoji Clinic, Osaka, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Shoji Clinic, Osaka</wicri:regionArea>
<wicri:noRegion>Osaka</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kuwana, Kayoko" sort="Kuwana, Kayoko" uniqKey="Kuwana K" first="Kayoko" last="Kuwana">Kayoko Kuwana</name>
<affiliation wicri:level="1"><nlm:aff id="af1-bctt-4-125">Department of Surgery, Kansai Medical University, Hirakata, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Surgery, Kansai Medical University, Hirakata</wicri:regionArea>
<wicri:noRegion>Hirakata</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kwon, A Hon" sort="Kwon, A Hon" uniqKey="Kwon A" first="A-Hon" last="Kwon">A-Hon Kwon</name>
<affiliation wicri:level="1"><nlm:aff id="af1-bctt-4-125">Department of Surgery, Kansai Medical University, Hirakata, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Surgery, Kansai Medical University, Hirakata</wicri:regionArea>
<wicri:noRegion>Hirakata</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">24367200</idno>
<idno type="pmc">3846707</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846707</idno>
<idno type="RBID">PMC:3846707</idno>
<idno type="doi">10.2147/BCTT.S36054</idno>
<date when="2012">2012</date>
<idno type="wicri:Area/Pmc/Corpus">002D01</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002D01</idno>
<idno type="wicri:Area/Pmc/Curation">002D00</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002D00</idno>
<idno type="wicri:Area/Pmc/Checkpoint">002999</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002999</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">002330</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002330</idno>
<idno type="wicri:Area/PubMed/Curation">002330</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002330</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002330</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002330</idno>
<idno type="wicri:Area/Ncbi/Merge">006096</idno>
<idno type="wicri:Area/Ncbi/Curation">006096</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">006096</idno>
<idno type="wicri:Area/Main/Merge">004315</idno>
<idno type="wicri:Area/Main/Curation">004297</idno>
<idno type="wicri:Area/Main/Exploration">004297</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Five-year follow-up of treatment outcomes in patients with early-stage breast cancer and clinically negative axillary nodes treated with no lymph node dissection or axillary clearance</title>
<author><name sortKey="Yamamoto, Daigo" sort="Yamamoto, Daigo" uniqKey="Yamamoto D" first="Daigo" last="Yamamoto">Daigo Yamamoto</name>
<affiliation wicri:level="1"><nlm:aff id="af1-bctt-4-125">Department of Surgery, Kansai Medical University, Hirakata, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Surgery, Kansai Medical University, Hirakata</wicri:regionArea>
<wicri:noRegion>Hirakata</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tanaka, Kanji" sort="Tanaka, Kanji" uniqKey="Tanaka K" first="Kanji" last="Tanaka">Kanji Tanaka</name>
<affiliation wicri:level="1"><nlm:aff id="af2-bctt-4-125">Ribon-Rose Tanaka Kanji Breast Clinic, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Ribon-Rose Tanaka Kanji Breast Clinic</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tsubota, Yu" sort="Tsubota, Yu" uniqKey="Tsubota Y" first="Yu" last="Tsubota">Yu Tsubota</name>
<affiliation wicri:level="1"><nlm:aff id="af1-bctt-4-125">Department of Surgery, Kansai Medical University, Hirakata, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Surgery, Kansai Medical University, Hirakata</wicri:regionArea>
<wicri:noRegion>Hirakata</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sueoka, Noriko" sort="Sueoka, Noriko" uniqKey="Sueoka N" first="Noriko" last="Sueoka">Noriko Sueoka</name>
<affiliation wicri:level="1"><nlm:aff id="af1-bctt-4-125">Department of Surgery, Kansai Medical University, Hirakata, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Surgery, Kansai Medical University, Hirakata</wicri:regionArea>
<wicri:noRegion>Hirakata</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shoji, Tetsuji" sort="Shoji, Tetsuji" uniqKey="Shoji T" first="Tetsuji" last="Shoji">Tetsuji Shoji</name>
<affiliation wicri:level="1"><nlm:aff id="af3-bctt-4-125">Shoji Clinic, Osaka, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Shoji Clinic, Osaka</wicri:regionArea>
<wicri:noRegion>Osaka</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kuwana, Kayoko" sort="Kuwana, Kayoko" uniqKey="Kuwana K" first="Kayoko" last="Kuwana">Kayoko Kuwana</name>
<affiliation wicri:level="1"><nlm:aff id="af1-bctt-4-125">Department of Surgery, Kansai Medical University, Hirakata, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Surgery, Kansai Medical University, Hirakata</wicri:regionArea>
<wicri:noRegion>Hirakata</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kwon, A Hon" sort="Kwon, A Hon" uniqKey="Kwon A" first="A-Hon" last="Kwon">A-Hon Kwon</name>
<affiliation wicri:level="1"><nlm:aff id="af1-bctt-4-125">Department of Surgery, Kansai Medical University, Hirakata, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Surgery, Kansai Medical University, Hirakata</wicri:regionArea>
<wicri:noRegion>Hirakata</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Breast Cancer : Targets and Therapy</title>
<idno type="eISSN">1179-1314</idno>
<imprint><date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>Sentinel lymph node biopsy has steadily replaced axillary lymph node dissection (ALND) for staging clinically node-negative breast cancer. However, ALND remains standard management of the axilla when a tumor-positive sentinel lymph node is identified.</p>
</sec>
<sec><title>Methods</title>
<p>We identified 460 patients with breast cancer (clinically T1/T2N0M0) from the database for 1999–2004. Patient age ranged from 26 to 81 (median 50) years. Patients who underwent mastectomy or breast-conserving surgery with or without ALND were compared for regional recurrence, disease-free survival, and overall survival.</p>
</sec>
<sec><title>Results</title>
<p>Patients with ALND (n = 308) were compared with the no ALND group (n = 152). Five-year overall survival and disease-free survival were not significantly different between the two groups, while there was a significant difference between them for regional recurrence. Of the 152 patients who did not undergo axillary dissection, four developed ipsilateral axillary disease, most of whom were rescued by delayed axillary dissection. Further, the criterion for identifying lymphedema was used, ie, a 2 cm circumferential change at any measured location. As a result, the incidence of lymphedema in the ALND group was 12.7%, while it was not seen in the non ALND group.</p>
</sec>
<sec><title>Conclusion</title>
<p>There is a possibility that ALND may be omitted for cT1/T2N0M0 breast cancer through a combination of hormone therapy and adjuvant chemotherapy.</p>
</sec>
</div>
</front>
</TEI>
<affiliations><list><country><li>Japon</li>
</country>
</list>
<tree><country name="Japon"><noRegion><name sortKey="Yamamoto, Daigo" sort="Yamamoto, Daigo" uniqKey="Yamamoto D" first="Daigo" last="Yamamoto">Daigo Yamamoto</name>
</noRegion>
<name sortKey="Kuwana, Kayoko" sort="Kuwana, Kayoko" uniqKey="Kuwana K" first="Kayoko" last="Kuwana">Kayoko Kuwana</name>
<name sortKey="Kwon, A Hon" sort="Kwon, A Hon" uniqKey="Kwon A" first="A-Hon" last="Kwon">A-Hon Kwon</name>
<name sortKey="Shoji, Tetsuji" sort="Shoji, Tetsuji" uniqKey="Shoji T" first="Tetsuji" last="Shoji">Tetsuji Shoji</name>
<name sortKey="Sueoka, Noriko" sort="Sueoka, Noriko" uniqKey="Sueoka N" first="Noriko" last="Sueoka">Noriko Sueoka</name>
<name sortKey="Tanaka, Kanji" sort="Tanaka, Kanji" uniqKey="Tanaka K" first="Kanji" last="Tanaka">Kanji Tanaka</name>
<name sortKey="Tsubota, Yu" sort="Tsubota, Yu" uniqKey="Tsubota Y" first="Yu" last="Tsubota">Yu Tsubota</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004297 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004297 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:3846707
   |texte=   Five-year follow-up of treatment outcomes in patients with early-stage breast cancer and clinically negative axillary nodes treated with no lymph node dissection or axillary clearance
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:24367200" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a LymphedemaV1

This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024

Serveur d'exploration sur le lymphœdème

Five-year follow-up of treatment outcomes in patients with early-stage breast cancer and clinically negative axillary nodes treated with no lymph node dissection or axillary clearance

Five-year follow-up of treatment outcomes in patients with early-stage breast cancer and clinically negative axillary nodes treated with no lymph node dissection or axillary clearance

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.