Dysphagia in Head and Neck Cancer Patients: Pretreatment Evaluation, Predictive Factors, and Assessment during Radio-Chemotherapy, Recommendations
Identifieur interne : 003699 ( Main/Exploration ); précédent : 003698; suivant : 003700Dysphagia in Head and Neck Cancer Patients: Pretreatment Evaluation, Predictive Factors, and Assessment during Radio-Chemotherapy, Recommendations
Auteurs : Nerina Denaro [Italie] ; Marco C. Merlano [Italie] ; Elvio G. Russi [Italie]Source :
- Clinical and Experimental Otorhinolaryngology [ 1976-8710 ] ; 2013.
Abstract
Progress in head and neck cancer (HNC) therapies has improved tumor response, loco-regional control, and survival. However, treatment intensification also increases early and late toxicities. Dysphagia is an underestimated symptom in HNC patients. Impairment of swallowing process could cause malnutrition, dehydration, aspiration, and pneumonia. A comprehensive literature review finalized in May 2012 included searches of electronic databases (Medline, Embase, and CAB abstracts) and scientific societies meetings materials (American Society of Clinical Oncology, Associazione Italiana Radioterapia Oncologica, Associazione Italiana di Oncologia Cervico-Cefalica, American Head and Neck Society, and European Society for Medical Oncology). Hand-searches of HNC journals and reference lists were carried out. Approximately one-third of dysphagia patients developed pneumonia requiring treatment. Aspiration pneumonia associated mortality ranged from 20% to 65%. Unidentified dysphagia caused significant morbidity, increased mortality, and decreased the quality of life. In this review we underline definition, causes, predictive factors of dysphagia and report on pretreatment and on-treatment evaluation, suggesting some key points to avoid underestimation. A multi-parameter assessment of swallowing problems may allow an earlier diagnosis. An appropriate evaluation might lead to a better treatment of both symptoms and cancer.
Url:
DOI: 10.3342/ceo.2013.6.3.117
PubMed: 24069513
PubMed Central: 3781223
Affiliations:
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Merlano</name><affiliation wicri:level="1"><nlm:aff id="A1">Oncology Department, Azienda Ospedaliera Santa Croce e Carle, Cuneo, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Oncology Department, Azienda Ospedaliera Santa Croce e Carle, Cuneo</wicri:regionArea><wicri:noRegion>Cuneo</wicri:noRegion></affiliation></author><author><name sortKey="Russi, Elvio G" sort="Russi, Elvio G" uniqKey="Russi E" first="Elvio G." last="Russi">Elvio G. Russi</name><affiliation wicri:level="1"><nlm:aff id="A2">Radiation Oncology Department, Azienda Ospedaliera Santa Croce e Carle, Cuneo, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Radiation Oncology Department, Azienda Ospedaliera Santa Croce e Carle, Cuneo</wicri:regionArea><wicri:noRegion>Cuneo</wicri:noRegion></affiliation></author></analytic><series><title level="j">Clinical and Experimental Otorhinolaryngology</title><idno type="ISSN">1976-8710</idno><idno type="eISSN">2005-0720</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Progress in head and neck cancer (HNC) therapies has improved tumor response, loco-regional control, and survival. However, treatment intensification also increases early and late toxicities. Dysphagia is an underestimated symptom in HNC patients. Impairment of swallowing process could cause malnutrition, dehydration, aspiration, and pneumonia. A comprehensive literature review finalized in May 2012 included searches of electronic databases (Medline, Embase, and CAB abstracts) and scientific societies meetings materials (American Society of Clinical Oncology, Associazione Italiana Radioterapia Oncologica, Associazione Italiana di Oncologia Cervico-Cefalica, American Head and Neck Society, and European Society for Medical Oncology). Hand-searches of HNC journals and reference lists were carried out. Approximately one-third of dysphagia patients developed pneumonia requiring treatment. Aspiration pneumonia associated mortality ranged from 20% to 65%. Unidentified dysphagia caused significant morbidity, increased mortality, and decreased the quality of life. In this review we underline definition, causes, predictive factors of dysphagia and report on pretreatment and on-treatment evaluation, suggesting some key points to avoid underestimation. A multi-parameter assessment of swallowing problems may allow an earlier diagnosis. 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Lewin</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Italie</li></country></list><tree><country name="Italie"><noRegion><name sortKey="Denaro, Nerina" sort="Denaro, Nerina" uniqKey="Denaro N" first="Nerina" last="Denaro">Nerina Denaro</name></noRegion><name sortKey="Merlano, Marco C" sort="Merlano, Marco C" uniqKey="Merlano M" first="Marco C." last="Merlano">Marco C. Merlano</name><name sortKey="Russi, Elvio G" sort="Russi, Elvio G" uniqKey="Russi E" first="Elvio G." last="Russi">Elvio G. Russi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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