Quasi-Complete Response of Classic Kaposi's Sarcoma Treated with Weekly Paclitaxel
Identifieur interne : 003243 ( Main/Exploration ); précédent : 003242; suivant : 003244Quasi-Complete Response of Classic Kaposi's Sarcoma Treated with Weekly Paclitaxel
Auteurs : Zineb Benbrahim [Maroc] ; Samia Arifi [Maroc] ; Hafida Benhammane [Maroc] ; Kaoutar Inani [Maroc] ; Salim Gallouj [Maroc] ; Meriem Meziane [Maroc] ; Fatima Zahra Mernissi [Maroc] ; Nawfel Mellas [Maroc] ; Omar El Mesbahi [Maroc]Source :
- Case Reports in Oncological Medicine [ 2090-6706 ] ; 2013.
Abstract
Classic Kaposi's sarcoma (CKS) is a subtype that traditionally occurs in elderly HIV-negative males of Mediterranean origin. Patients with CKS characteristically present with skin lesions in the distal extremities. Involvement of the viscera is uncommon but may occur in the late stages of the disease. Patients with extensive KS can be treated with systemic chemotherapy. A number of drugs approved for treatment of AIDS-associated KS, especially Paclitaxel, have activity against CKS after failure of prior therapy. We report a patient treated with weekly Paclitaxel, as initial chemotherapy, for CKS presenting with multiple visceral involvement and having a contraindication for Bleomycin. The patient had quasi-complete response after three months of chemotherapy suggesting that weekly Paclitaxel might be effective as a first-line therapy for classical type KS with visceral involvement.
Url:
DOI: 10.1155/2013/196878
PubMed: 23476845
PubMed Central: 3586472
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 003C93
- to stream Pmc, to step Curation: 003C92
- to stream Pmc, to step Checkpoint: 002030
- to stream Ncbi, to step Merge: 005684
- to stream Ncbi, to step Curation: 005684
- to stream Ncbi, to step Checkpoint: 005684
- to stream Main, to step Merge: 003248
- to stream Main, to step Curation: 003243
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Quasi-Complete Response of Classic Kaposi's Sarcoma Treated with Weekly Paclitaxel</title><author><name sortKey="Benbrahim, Zineb" sort="Benbrahim, Zineb" uniqKey="Benbrahim Z" first="Zineb" last="Benbrahim">Zineb Benbrahim</name><affiliation wicri:level="1"><nlm:aff id="I1">Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="Arifi, Samia" sort="Arifi, Samia" uniqKey="Arifi S" first="Samia" last="Arifi">Samia Arifi</name><affiliation wicri:level="1"><nlm:aff id="I1">Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="Benhammane, Hafida" sort="Benhammane, Hafida" uniqKey="Benhammane H" first="Hafida" last="Benhammane">Hafida Benhammane</name><affiliation wicri:level="1"><nlm:aff id="I1">Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="Inani, Kaoutar" sort="Inani, Kaoutar" uniqKey="Inani K" first="Kaoutar" last="Inani">Kaoutar Inani</name><affiliation wicri:level="1"><nlm:aff id="I2">Service of Dermatology, Hassan II University Hospital, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Service of Dermatology, Hassan II University Hospital, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="Gallouj, Salim" sort="Gallouj, Salim" uniqKey="Gallouj S" first="Salim" last="Gallouj">Salim Gallouj</name><affiliation wicri:level="1"><nlm:aff id="I2">Service of Dermatology, Hassan II University Hospital, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Service of Dermatology, Hassan II University Hospital, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="Meziane, Meriem" sort="Meziane, Meriem" uniqKey="Meziane M" first="Meriem" last="Meziane">Meriem Meziane</name><affiliation wicri:level="1"><nlm:aff id="I2">Service of Dermatology, Hassan II University Hospital, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Service of Dermatology, Hassan II University Hospital, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="Mernissi, Fatima Zahra" sort="Mernissi, Fatima Zahra" uniqKey="Mernissi F" first="Fatima Zahra" last="Mernissi">Fatima Zahra Mernissi</name><affiliation wicri:level="1"><nlm:aff id="I2">Service of Dermatology, Hassan II University Hospital, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Service of Dermatology, Hassan II University Hospital, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="Mellas, Nawfel" sort="Mellas, Nawfel" uniqKey="Mellas N" first="Nawfel" last="Mellas">Nawfel Mellas</name><affiliation wicri:level="1"><nlm:aff id="I1">Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="El Mesbahi, Omar" sort="El Mesbahi, Omar" uniqKey="El Mesbahi O" first="Omar" last="El Mesbahi">Omar El Mesbahi</name><affiliation wicri:level="1"><nlm:aff id="I1">Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23476845</idno><idno type="pmc">3586472</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586472</idno><idno type="RBID">PMC:3586472</idno><idno type="doi">10.1155/2013/196878</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">003C93</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003C93</idno><idno type="wicri:Area/Pmc/Curation">003C92</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003C92</idno><idno type="wicri:Area/Pmc/Checkpoint">002030</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002030</idno><idno type="wicri:Area/Ncbi/Merge">005684</idno><idno type="wicri:Area/Ncbi/Curation">005684</idno><idno type="wicri:Area/Ncbi/Checkpoint">005684</idno><idno type="wicri:doubleKey">2090-6706:2013:Benbrahim Z:quasi:complete:response</idno><idno type="wicri:Area/Main/Merge">003248</idno><idno type="wicri:Area/Main/Curation">003243</idno><idno type="wicri:Area/Main/Exploration">003243</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Quasi-Complete Response of Classic Kaposi's Sarcoma Treated with Weekly Paclitaxel</title><author><name sortKey="Benbrahim, Zineb" sort="Benbrahim, Zineb" uniqKey="Benbrahim Z" first="Zineb" last="Benbrahim">Zineb Benbrahim</name><affiliation wicri:level="1"><nlm:aff id="I1">Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="Arifi, Samia" sort="Arifi, Samia" uniqKey="Arifi S" first="Samia" last="Arifi">Samia Arifi</name><affiliation wicri:level="1"><nlm:aff id="I1">Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="Benhammane, Hafida" sort="Benhammane, Hafida" uniqKey="Benhammane H" first="Hafida" last="Benhammane">Hafida Benhammane</name><affiliation wicri:level="1"><nlm:aff id="I1">Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="Inani, Kaoutar" sort="Inani, Kaoutar" uniqKey="Inani K" first="Kaoutar" last="Inani">Kaoutar Inani</name><affiliation wicri:level="1"><nlm:aff id="I2">Service of Dermatology, Hassan II University Hospital, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Service of Dermatology, Hassan II University Hospital, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="Gallouj, Salim" sort="Gallouj, Salim" uniqKey="Gallouj S" first="Salim" last="Gallouj">Salim Gallouj</name><affiliation wicri:level="1"><nlm:aff id="I2">Service of Dermatology, Hassan II University Hospital, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Service of Dermatology, Hassan II University Hospital, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="Meziane, Meriem" sort="Meziane, Meriem" uniqKey="Meziane M" first="Meriem" last="Meziane">Meriem Meziane</name><affiliation wicri:level="1"><nlm:aff id="I2">Service of Dermatology, Hassan II University Hospital, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Service of Dermatology, Hassan II University Hospital, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="Mernissi, Fatima Zahra" sort="Mernissi, Fatima Zahra" uniqKey="Mernissi F" first="Fatima Zahra" last="Mernissi">Fatima Zahra Mernissi</name><affiliation wicri:level="1"><nlm:aff id="I2">Service of Dermatology, Hassan II University Hospital, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Service of Dermatology, Hassan II University Hospital, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="Mellas, Nawfel" sort="Mellas, Nawfel" uniqKey="Mellas N" first="Nawfel" last="Mellas">Nawfel Mellas</name><affiliation wicri:level="1"><nlm:aff id="I1">Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author><author><name sortKey="El Mesbahi, Omar" sort="El Mesbahi, Omar" uniqKey="El Mesbahi O" first="Omar" last="El Mesbahi">Omar El Mesbahi</name><affiliation wicri:level="1"><nlm:aff id="I1">Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès</wicri:regionArea><wicri:noRegion>Fès</wicri:noRegion></affiliation></author></analytic><series><title level="j">Case Reports in Oncological Medicine</title><idno type="ISSN">2090-6706</idno><idno type="eISSN">2090-6714</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Classic Kaposi's sarcoma (CKS) is a subtype that traditionally occurs in elderly HIV-negative males of Mediterranean origin. Patients with CKS characteristically present with skin lesions in the distal extremities. Involvement of the viscera is uncommon but may occur in the late stages of the disease. Patients with extensive KS can be treated with systemic chemotherapy. A number of drugs approved for treatment of AIDS-associated KS, especially Paclitaxel, have activity against CKS after failure of prior therapy. We report a patient treated with weekly Paclitaxel, as initial chemotherapy, for CKS presenting with multiple visceral involvement and having a contraindication for Bleomycin. The patient had quasi-complete response after three months of chemotherapy suggesting that weekly Paclitaxel might be effective as a first-line therapy for classical type KS with visceral involvement. </p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Brambilla, L" uniqKey="Brambilla L">L Brambilla</name></author><author><name sortKey="Miedico, A" uniqKey="Miedico A">A Miedico</name></author><author><name sortKey="Ferrucci, S" uniqKey="Ferrucci S">S Ferrucci</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brambilla, L" uniqKey="Brambilla L">L Brambilla</name></author><author><name sortKey="Labianca, R" uniqKey="Labianca R">R Labianca</name></author><author><name sortKey="Boneschi, V" uniqKey="Boneschi V">V Boneschi</name></author><author><name sortKey="Fossati, S" uniqKey="Fossati S">S Fossati</name></author><author><name sortKey="Finzi, Af" uniqKey="Finzi A">AF Finzi</name></author><author><name sortKey="Luporini, G" uniqKey="Luporini G">G Luporini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Di Lorenzo, G" uniqKey="Di Lorenzo G">G Di Lorenzo</name></author><author><name sortKey="Kreuter, A" uniqKey="Kreuter A">A Kreuter</name></author><author><name sortKey="Di Trolio, R" uniqKey="Di Trolio R">R Di Trolio</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brambilla, L" uniqKey="Brambilla L">L Brambilla</name></author><author><name sortKey="Labianca, R" uniqKey="Labianca R">R Labianca</name></author><author><name sortKey="Ferrucci, Sm" uniqKey="Ferrucci S">SM Ferrucci</name></author><author><name sortKey="Taglioni, M" uniqKey="Taglioni M">M Taglioni</name></author><author><name sortKey="Boneschi, V" uniqKey="Boneschi V">V Boneschi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chao, Sc" uniqKey="Chao S">SC Chao</name></author><author><name sortKey="Lee, Jyy" uniqKey="Lee J">JYY Lee</name></author><author><name sortKey="Tsao, Cj" uniqKey="Tsao C">CJ Tsao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gao, Sj" uniqKey="Gao S">SJ Gao</name></author><author><name sortKey="Kingsley, L" uniqKey="Kingsley L">L Kingsley</name></author><author><name sortKey="Hoover, Dr" uniqKey="Hoover D">DR Hoover</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kaiserling, E" uniqKey="Kaiserling E">E Kaiserling</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Iscovich, J" uniqKey="Iscovich J">J Iscovich</name></author><author><name sortKey="Boffetta, P" uniqKey="Boffetta P">P Boffetta</name></author><author><name sortKey="Brennan, P" uniqKey="Brennan P">P Brennan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Engin, H" uniqKey="Engin H">H Engin</name></author><author><name sortKey="Celik, I" uniqKey="Celik I">I Çelik</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fardet, L" uniqKey="Fardet L">L Fardet</name></author><author><name sortKey="Stoebner, Pe" uniqKey="Stoebner P">PE Stoebner</name></author><author><name sortKey="Bachelez, H" uniqKey="Bachelez H">H Bachelez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brambilla, L" uniqKey="Brambilla L">L Brambilla</name></author><author><name sortKey="Romanelli, A" uniqKey="Romanelli A">A Romanelli</name></author><author><name sortKey="Bellinvia, M" uniqKey="Bellinvia M">M Bellinvia</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Maroc</li></country></list><tree><country name="Maroc"><noRegion><name sortKey="Benbrahim, Zineb" sort="Benbrahim, Zineb" uniqKey="Benbrahim Z" first="Zineb" last="Benbrahim">Zineb Benbrahim</name></noRegion><name sortKey="Arifi, Samia" sort="Arifi, Samia" uniqKey="Arifi S" first="Samia" last="Arifi">Samia Arifi</name><name sortKey="Benhammane, Hafida" sort="Benhammane, Hafida" uniqKey="Benhammane H" first="Hafida" last="Benhammane">Hafida Benhammane</name><name sortKey="El Mesbahi, Omar" sort="El Mesbahi, Omar" uniqKey="El Mesbahi O" first="Omar" last="El Mesbahi">Omar El Mesbahi</name><name sortKey="Gallouj, Salim" sort="Gallouj, Salim" uniqKey="Gallouj S" first="Salim" last="Gallouj">Salim Gallouj</name><name sortKey="Inani, Kaoutar" sort="Inani, Kaoutar" uniqKey="Inani K" first="Kaoutar" last="Inani">Kaoutar Inani</name><name sortKey="Mellas, Nawfel" sort="Mellas, Nawfel" uniqKey="Mellas N" first="Nawfel" last="Mellas">Nawfel Mellas</name><name sortKey="Mernissi, Fatima Zahra" sort="Mernissi, Fatima Zahra" uniqKey="Mernissi F" first="Fatima Zahra" last="Mernissi">Fatima Zahra Mernissi</name><name sortKey="Meziane, Meriem" sort="Meziane, Meriem" uniqKey="Meziane M" first="Meriem" last="Meziane">Meriem Meziane</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003243 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003243 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:3586472
|texte= Quasi-Complete Response of Classic Kaposi's Sarcoma Treated with Weekly Paclitaxel
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:23476845" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |