LymphedemaV1, Main, Exploration, bibRecord, 002E53

A Novel Eliminase from a Marine Bacterium That Degrades Hyaluronan and Chondroitin Sulfate*

Identifieur interne : 002E53 ( Main/Exploration ); précédent : 002E52; suivant : 002E54

A Novel Eliminase from a Marine Bacterium That Degrades Hyaluronan and Chondroitin Sulfate*

Auteurs : Wenjun Han [République populaire de Chine] ; Wenshuang Wang [République populaire de Chine] ; Mei Zhao [République populaire de Chine] ; Kazuyuki Sugahara [Japon] ; Fuchuan Li [République populaire de Chine]

Source :

The Journal of Biological Chemistry [ 0021-9258 ] ; 2014.

RBID : PMC:4183822

Abstract

Background: Glycosaminoglycan (GAG) lyases have been widely isolated from terrestrial but not marine bacteria.

Results: A novel GAG lyase (HCLase) was identified for the first time from a marine bacterium.

Conclusion: The HCLase has very low homology to the characterized conventional GAG lyases and possesses very unique biochemical characteristics.

Significance: HCLase will be useful for chondroitin sulfate/hyaluronan-related research and applications.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183822

DOI: 10.1074/jbc.M114.590752
PubMed: 25122756
PubMed Central: 4183822

Affiliations:

Japon, République populaire de Chine

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p><bold>Background:</bold>
 Glycosaminoglycan (GAG) lyases have been widely isolated from terrestrial but not marine bacteria.</p>
<p><bold>Results:</bold>
 A novel GAG lyase (HCLase) was identified for the first time from a marine bacterium.</p>
<p><bold>Conclusion:</bold>
 The HCLase has very low homology to the characterized conventional GAG lyases and possesses very unique biochemical characteristics.</p>
<p><bold>Significance:</bold>
 HCLase will be useful for chondroitin sulfate/hyaluronan-related research and applications.</p>
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A Novel Eliminase from a Marine Bacterium That Degrades Hyaluronan and Chondroitin Sulfate*

A Novel Eliminase from a Marine Bacterium That Degrades Hyaluronan and Chondroitin Sulfate*

Source :

Abstract

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