A review of performance of near-infrared fluorescence imaging devices used in clinical studies
Identifieur interne : 002E14 ( Main/Exploration ); précédent : 002E13; suivant : 002E15A review of performance of near-infrared fluorescence imaging devices used in clinical studies
Auteurs : B. Zhu ; E M Sevick-MuracaSource :
- The British Journal of Radiology [ 0007-1285 ] ; 2014.
Abstract
Near-infrared fluorescence (NIRF) molecular imaging holds great promise as a new “point-of-care” medical imaging modality that can potentially provide the sensitivity of nuclear medicine techniques, but without the radioactivity that can otherwise place limitations of usage. Recently, NIRF imaging devices of a variety of designs have emerged in the market and in investigational clinical studies using indocyanine green (ICG) as a non-targeting NIRF contrast agent to demark the blood and lymphatic vasculatures both non-invasively and intraoperatively. Approved in the USA since 1956 for intravenous administration, ICG has been more recently used off label in intradermal or subcutaneous administrations for fluorescence imaging of the lymphatic vasculature and lymph nodes. Herein, we summarize the devices of a variety of designs, summarize their performance in lymphatic imaging in a tabular format and comment on necessary efforts to develop standards for device performance to compare and use these emerging devices in future, NIRF molecular imaging studies.
Url:
DOI: 10.1259/bjr.20140547
PubMed: 25410320
PubMed Central: 4277384
Affiliations:
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