Angiosarcoma Developing in a Vagal Schwannoma: A Rare Case Report
Identifieur interne : 002D53 ( Main/Exploration ); précédent : 002D52; suivant : 002D54Angiosarcoma Developing in a Vagal Schwannoma: A Rare Case Report
Auteurs : Vrushali Mahajan [Inde] ; Seema Rao [Inde] ; Pallav Gupta [Inde] ; Manish Munjal [Inde] ; Sangeet Agrawal [Inde]Source :
- Head and Neck Pathology [ 1936-055X ] ; 2014.
Abstract
Angiosarcoma arising in a schwannoma is extremely rare with only fourteen cases having been reported in the literature to the best of our knowledge. Amongst these fourteen, only five cases developed from vagal schwannoma. We describe a case of epithelioid angiosarcoma arising in a long standing vagal schwannoma in a 41 years male patient. Grossly the tumor was well encapsulated with variegated cut surface. On microscopy the tumor had two distinct components composed of benign schwannoma and malignant angiosarcoma which were further confirmed by immunohistochemistry. On further work up, he was found to have multiple distant metastases. This is the sixth reported case of angiosarcoma arising in a vagal schwannoma. The proposed histogenesis of this rare transformation, its prognostic factors and a review of literature regarding this entity is discussed.
Url:
DOI: 10.1007/s12105-014-0577-x
PubMed: 25371276
PubMed Central: 4542800
Affiliations:
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type="abstract" xml:lang="en"><p>Angiosarcoma arising in a schwannoma is extremely rare with only fourteen cases having been reported in the literature to the best of our knowledge. Amongst these fourteen, only five cases developed from vagal schwannoma. We describe a case of epithelioid angiosarcoma arising in a long standing vagal schwannoma in a 41 years male patient. Grossly the tumor was well encapsulated with variegated cut surface. On microscopy the tumor had two distinct components composed of benign schwannoma and malignant angiosarcoma which were further confirmed by immunohistochemistry. On further work up, he was found to have multiple distant metastases. This is the sixth reported case of angiosarcoma arising in a vagal schwannoma. The proposed histogenesis of this rare transformation, its prognostic factors and a review of literature regarding this entity is discussed.</p></div></front></TEI><affiliations><list><country><li>Inde</li></country></list><tree><country name="Inde"><noRegion><name sortKey="Mahajan, Vrushali" sort="Mahajan, Vrushali" uniqKey="Mahajan V" first="Vrushali" last="Mahajan">Vrushali Mahajan</name></noRegion><name sortKey="Agrawal, Sangeet" sort="Agrawal, Sangeet" uniqKey="Agrawal S" first="Sangeet" last="Agrawal">Sangeet Agrawal</name><name sortKey="Gupta, Pallav" sort="Gupta, Pallav" uniqKey="Gupta P" first="Pallav" last="Gupta">Pallav Gupta</name><name sortKey="Munjal, Manish" sort="Munjal, Manish" uniqKey="Munjal M" first="Manish" last="Munjal">Manish Munjal</name><name sortKey="Rao, Seema" sort="Rao, Seema" uniqKey="Rao S" first="Seema" last="Rao">Seema Rao</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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