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Is axillary lymph node dissection necessary after sentinel lymph node biopsy in patients with mastectomy and pathological N1 breast cancer?

Identifieur interne : 002961 ( Main/Exploration ); précédent : 002960; suivant : 002962

Is axillary lymph node dissection necessary after sentinel lymph node biopsy in patients with mastectomy and pathological N1 breast cancer?

Auteurs : Yun Fu [États-Unis] ; Debra Chung ; Minh-An Cao ; Sophia Apple ; Helena Chang

Source :

RBID : pubmed:25081336

Descripteurs français

English descriptors

Abstract

The American College of Surgeons Oncology Group (ACOSOG) Z0011 trial reported that axillary lymph node dissection (ALND) did not change the recurrence and overall survival (OS) rates in patients with lumpectomy and one to two positive nodes detected by sentinel lymph node biopsy (SLNB). The aim of this study was to determine whether patients with mastectomy and pathological N1 disease found by SLNB could forego ALND.

DOI: 10.1245/s10434-014-3814-3
PubMed: 25081336


Affiliations:


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Le document en format XML

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<nlm:affiliation>Department of Surgery, David Geffen School of Medicine, UCLA, Revlon/UCLA Breast Center, Los Angeles, California, USA.</nlm:affiliation>
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<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Axilla (surgery)</term>
<term>Biomarkers, Tumor (blood)</term>
<term>Breast Neoplasms (blood)</term>
<term>Breast Neoplasms (diagnosis)</term>
<term>Breast Neoplasms (mortality)</term>
<term>Breast Neoplasms (radiotherapy)</term>
<term>Breast Neoplasms (surgery)</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Indoles</term>
<term>Lymph Node Excision (methods)</term>
<term>Mastectomy</term>
<term>Middle Aged</term>
<term>Neoplasm Invasiveness</term>
<term>Neoplasm Staging</term>
<term>Phenylpropionates</term>
<term>Predictive Value of Tests</term>
<term>Proportional Hazards Models</term>
<term>Radiotherapy, Adjuvant</term>
<term>Receptor, ErbB-2 (blood)</term>
<term>Retrospective Studies</term>
<term>Sensitivity and Specificity</term>
<term>Sentinel Lymph Node Biopsy</term>
<term>Survival Analysis</term>
<term>Treatment Outcome</term>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Aisselle ()</term>
<term>Analyse de survie</term>
<term>Biopsie de noeud lymphatique sentinelle</term>
<term>Femelle</term>
<term>Humains</term>
<term>Indoles</term>
<term>Invasion tumorale</term>
<term>Lymphadénectomie ()</term>
<term>Marqueurs biologiques tumoraux (sang)</term>
<term>Mastectomie</term>
<term>Modèles de hasards proportionnels</term>
<term>Phénylpropionates</term>
<term>Radiothérapie adjuvante</term>
<term>Récepteur ErbB-2 (sang)</term>
<term>Résultat thérapeutique</term>
<term>Sensibilité et spécificité</term>
<term>Stade de la tumeur</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tumeurs du sein ()</term>
<term>Tumeurs du sein (diagnostic)</term>
<term>Tumeurs du sein (mortalité)</term>
<term>Tumeurs du sein (radiothérapie)</term>
<term>Tumeurs du sein (sang)</term>
<term>Valeur prédictive des tests</term>
<term>Études de suivi</term>
<term>Études rétrospectives</term>
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<term>Breast Neoplasms</term>
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<term>Tumeurs du sein</term>
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<term>Lymph Node Excision</term>
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<term>Breast Neoplasms</term>
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<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
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<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Indoles</term>
<term>Mastectomy</term>
<term>Middle Aged</term>
<term>Neoplasm Invasiveness</term>
<term>Neoplasm Staging</term>
<term>Phenylpropionates</term>
<term>Predictive Value of Tests</term>
<term>Proportional Hazards Models</term>
<term>Radiotherapy, Adjuvant</term>
<term>Retrospective Studies</term>
<term>Sensitivity and Specificity</term>
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<term>Survival Analysis</term>
<term>Treatment Outcome</term>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Aisselle</term>
<term>Analyse de survie</term>
<term>Biopsie de noeud lymphatique sentinelle</term>
<term>Femelle</term>
<term>Humains</term>
<term>Indoles</term>
<term>Invasion tumorale</term>
<term>Lymphadénectomie</term>
<term>Mastectomie</term>
<term>Modèles de hasards proportionnels</term>
<term>Phénylpropionates</term>
<term>Radiothérapie adjuvante</term>
<term>Résultat thérapeutique</term>
<term>Sensibilité et spécificité</term>
<term>Stade de la tumeur</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tumeurs du sein</term>
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<term>Études de suivi</term>
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<front>
<div type="abstract" xml:lang="en">The American College of Surgeons Oncology Group (ACOSOG) Z0011 trial reported that axillary lymph node dissection (ALND) did not change the recurrence and overall survival (OS) rates in patients with lumpectomy and one to two positive nodes detected by sentinel lymph node biopsy (SLNB). The aim of this study was to determine whether patients with mastectomy and pathological N1 disease found by SLNB could forego ALND.</div>
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<name sortKey="Chang, Helena" sort="Chang, Helena" uniqKey="Chang H" first="Helena" last="Chang">Helena Chang</name>
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