Key concepts in management of vulvar cancer.
Identifieur interne : 002957 ( Main/Exploration ); précédent : 002956; suivant : 002958Key concepts in management of vulvar cancer.
Auteurs : Susan Zweizig [États-Unis] ; Sharmilee Korets [États-Unis] ; Joanna M. Cain [États-Unis]Source :
- Best practice & research. Clinical obstetrics & gynaecology [ 1532-1932 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- diagnostic : Tumeurs de la vulve.
- étiologie : Tumeurs de la vulve.
- Facteurs de risque, Femelle, Humains, Infections à papillomavirus, Papillomaviridae, Tumeurs de la vulve.
English descriptors
- KwdEn :
- MESH :
- complications : Papillomavirus Infections.
- diagnosis : Vulvar Neoplasms.
- etiology : Vulvar Neoplasms.
- therapy : Vulvar Neoplasms.
- Female, Humans, Papillomaviridae, Risk Factors.
Abstract
Vulvar carcinoma is an uncommon tumor that is seen most often in older women. Subtle symptoms such as pruritus should prompt examination and targeted biopsy in all women as this disease can be successfully treated even in elderly, frail individuals. Vulvar cancer has a bimodal age distribution and is seen in both young and older women with risk factors including human papillomavirus (HPV) infection, smoking, and vulvar skin diseases (i.e., lichen sclerosus). This cancer is staged surgically, with an update in 2009 incorporating prognostic factors. The treatment of vulvar carcinoma has evolved to include more conservative surgical techniques that provide improved cure rates with emphasis on minimizing morbidity. Advanced and metastatic lesions are now treated with chemoradiation which produces substantial cure rates with decreased morbidity. Promising areas of research in vulvar cancer include refinement of sentinel lymph node biopsy, prevention of lymphedema, and preservation of sexual function following treatment.
DOI: 10.1016/j.bpobgyn.2014.07.001
PubMed: 25151473
Affiliations:
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<front><div type="abstract" xml:lang="en">Vulvar carcinoma is an uncommon tumor that is seen most often in older women. Subtle symptoms such as pruritus should prompt examination and targeted biopsy in all women as this disease can be successfully treated even in elderly, frail individuals. Vulvar cancer has a bimodal age distribution and is seen in both young and older women with risk factors including human papillomavirus (HPV) infection, smoking, and vulvar skin diseases (i.e., lichen sclerosus). This cancer is staged surgically, with an update in 2009 incorporating prognostic factors. The treatment of vulvar carcinoma has evolved to include more conservative surgical techniques that provide improved cure rates with emphasis on minimizing morbidity. Advanced and metastatic lesions are now treated with chemoradiation which produces substantial cure rates with decreased morbidity. Promising areas of research in vulvar cancer include refinement of sentinel lymph node biopsy, prevention of lymphedema, and preservation of sexual function following treatment.</div>
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