Measuring impact on filarial infection status in a community study: role of coverage of mass drug administration (MDA).
Identifieur interne : 002845 ( Main/Exploration ); précédent : 002844; suivant : 002846Measuring impact on filarial infection status in a community study: role of coverage of mass drug administration (MDA).
Auteurs : Anil Kumar ; Pawan SachanSource :
- Tropical biomedicine [ 0127-5720 ] ; 2014.
Descripteurs français
- KwdFr :
- Albendazole (usage thérapeutique), Diéthylcarbamazine (usage thérapeutique), Filaricides (usage thérapeutique), Filariose lymphatique (traitement médicamenteux), Filariose lymphatique (épidémiologie), Humains, Inde (épidémiologie), Résultat thérapeutique, Traitement médicamenteux (), Utilisation médicament.
- MESH :
- traitement médicamenteux : Filariose lymphatique.
- usage thérapeutique : Albendazole, Diéthylcarbamazine, Filaricides.
- épidémiologie : Filariose lymphatique, Inde.
- Humains, Résultat thérapeutique, Traitement médicamenteux, Utilisation médicament.
- Wicri :
- geographic : Inde.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Albendazole, Diethylcarbamazine, Filaricides.
- geographic , epidemiology : India.
- drug therapy : Elephantiasis, Filarial.
- epidemiology : Elephantiasis, Filarial.
- methods : Drug Therapy.
- Drug Utilization, Humans, Treatment Outcome.
Abstract
Lymphatic filariasis is still endemic in many parts of India. The main strategy to implement mass drug administration with DEC and albendazole was added in 2006 to ensure increased impact on the microfilaria (mf) rate in the community. However, the effective coverage remained low in the community leading to lower than desired impact on the parasite population in human. This paper presents the dynamics of participation in annual repeated rounds of mass drug administration in some villages of Kanpur Nagar district in Uttar Pradesh and its impact over the infection rate. It is revealed that after 6 annual rounds of MDA, mf rate could only be reduced by 17.3% in population subgroups who participated only once in comparison to 88% in those who participated in 6 or all annual rounds.
PubMed: 25134891
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Lymphatic filariasis is still endemic in many parts of India. The main strategy to implement mass drug administration with DEC and albendazole was added in 2006 to ensure increased impact on the microfilaria (mf) rate in the community. However, the effective coverage remained low in the community leading to lower than desired impact on the parasite population in human. This paper presents the dynamics of participation in annual repeated rounds of mass drug administration in some villages of Kanpur Nagar district in Uttar Pradesh and its impact over the infection rate. It is revealed that after 6 annual rounds of MDA, mf rate could only be reduced by 17.3% in population subgroups who participated only once in comparison to 88% in those who participated in 6 or all annual rounds.</div>
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