Plasticity of Airway Lymphatics in Development and Disease
Identifieur interne : 002690 ( Main/Exploration ); précédent : 002689; suivant : 002691Plasticity of Airway Lymphatics in Development and Disease
Auteurs : Li-Chin Yao ; Donald M. McdonaldSource :
- Advances in anatomy, embryology, and cell biology [ 0301-5556 ] ; 2014.
Abstract
The dynamic nature of lymphatic vessels is reflected by structural and functional modifications that coincide with changes in their environment. Lymphatics in the respiratory tract undergo rapid changes around birth, during adaptation to air breathing, when lymphatic endothelial cells develop button-like intercellular junctions specialized for efficient fluid uptake and transport. In inflammatory conditions, lymphatic vessels proliferate and undergo remodeling to accommodate greater plasma leakage and immune cell trafficking. However, the newly formed lymphatics are abnormal, and resolution of inflammation is not accompanied by complete reversal of the lymphatic vessel changes back to the baseline. As the understanding of lymphatic plasticity advances, approaches for eliminating the abnormal vessels and improving the functionality of those that remain move closer to reality. This chapter provides an overview of what is known about lymphatic vessel growth, remodeling, and other forms of plasticity that occur during development or inflammation, with an emphasis on the respiratory tract. Also addressed is the limited reversibility of changes in lymphatics during the resolution of inflammation.
Url:
DOI: 10.1007/978-3-7091-1646-3_4
PubMed: 24276885
PubMed Central: 3955364
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 003401
- to stream Pmc, to step Curation: 003400
- to stream Pmc, to step Checkpoint: 001899
- to stream Ncbi, to step Merge: 005F91
- to stream Ncbi, to step Curation: 005F91
- to stream Ncbi, to step Checkpoint: 005F91
- to stream Main, to step Merge: 002694
- to stream Main, to step Curation: 002690
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Plasticity of Airway Lymphatics in Development and Disease</title><author><name sortKey="Yao, Li Chin" sort="Yao, Li Chin" uniqKey="Yao L" first="Li-Chin" last="Yao">Li-Chin Yao</name></author><author><name sortKey="Mcdonald, Donald M" sort="Mcdonald, Donald M" uniqKey="Mcdonald D" first="Donald M." last="Mcdonald">Donald M. Mcdonald</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24276885</idno><idno type="pmc">3955364</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955364</idno><idno type="RBID">PMC:3955364</idno><idno type="doi">10.1007/978-3-7091-1646-3_4</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">003401</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003401</idno><idno type="wicri:Area/Pmc/Curation">003400</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003400</idno><idno type="wicri:Area/Pmc/Checkpoint">001899</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001899</idno><idno type="wicri:Area/Ncbi/Merge">005F91</idno><idno type="wicri:Area/Ncbi/Curation">005F91</idno><idno type="wicri:Area/Ncbi/Checkpoint">005F91</idno><idno type="wicri:doubleKey">0301-5556:2014:Yao L:plasticity:of:airway</idno><idno type="wicri:Area/Main/Merge">002694</idno><idno type="wicri:Area/Main/Curation">002690</idno><idno type="wicri:Area/Main/Exploration">002690</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Plasticity of Airway Lymphatics in Development and Disease</title><author><name sortKey="Yao, Li Chin" sort="Yao, Li Chin" uniqKey="Yao L" first="Li-Chin" last="Yao">Li-Chin Yao</name></author><author><name sortKey="Mcdonald, Donald M" sort="Mcdonald, Donald M" uniqKey="Mcdonald D" first="Donald M." last="Mcdonald">Donald M. Mcdonald</name></author></analytic><series><title level="j">Advances in anatomy, embryology, and cell biology</title><idno type="ISSN">0301-5556</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">The dynamic nature of lymphatic vessels is reflected by structural and functional modifications that coincide with changes in their environment. Lymphatics in the respiratory tract undergo rapid changes around birth, during adaptation to air breathing, when lymphatic endothelial cells develop button-like intercellular junctions specialized for efficient fluid uptake and transport. In inflammatory conditions, lymphatic vessels proliferate and undergo remodeling to accommodate greater plasma leakage and immune cell trafficking. However, the newly formed lymphatics are abnormal, and resolution of inflammation is not accompanied by complete reversal of the lymphatic vessel changes back to the baseline. As the understanding of lymphatic plasticity advances, approaches for eliminating the abnormal vessels and improving the functionality of those that remain move closer to reality. This chapter provides an overview of what is known about lymphatic vessel growth, remodeling, and other forms of plasticity that occur during development or inflammation, with an emphasis on the respiratory tract. Also addressed is the limited reversibility of changes in lymphatics during the resolution of inflammation.</p></div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Mcdonald, Donald M" sort="Mcdonald, Donald M" uniqKey="Mcdonald D" first="Donald M." last="Mcdonald">Donald M. Mcdonald</name><name sortKey="Yao, Li Chin" sort="Yao, Li Chin" uniqKey="Yao L" first="Li-Chin" last="Yao">Li-Chin Yao</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002690 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002690 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:3955364
|texte= Plasticity of Airway Lymphatics in Development and Disease
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:24276885" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |