Groin surgery and risk of recurrence in lymph node positive patients with vulvar squamous cell carcinoma.
Identifieur interne : 001D29 ( Main/Exploration ); précédent : 001D28; suivant : 001D30Groin surgery and risk of recurrence in lymph node positive patients with vulvar squamous cell carcinoma.
Auteurs : Linda S. Nooij [Pays-Bas] ; Paulien J. Ongkiehong [Pays-Bas] ; Erik W. Van Zwet [Pays-Bas] ; Tjalling Bosse [Pays-Bas] ; Carien L. Creutzberg [Pays-Bas] ; Katja N. Gaarenstroom [Pays-Bas] ; Mariette I E. Van Poelgeest [Pays-Bas]Source :
- Gynecologic oncology [ 1095-6859 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Canal inguinal, Carcinome épidermoïde (), Carcinome épidermoïde (radiothérapie), Carcinome épidermoïde (secondaire), Facteurs de risque, Femelle, Humains, Interventions chirurgicales de cytoréduction, Lymphadénectomie (), Lymphadénectomie (effets indésirables), Métastase lymphatique, Noeuds lymphatiques (), Radiothérapie adjuvante, Récidive tumorale locale (anatomopathologie), Sujet âgé, Sujet âgé de 80 ans ou plus, Survie sans rechute, Taux de survie, Tumeurs de la vulve (), Tumeurs de la vulve (anatomopathologie), Tumeurs de la vulve (radiothérapie), Études rétrospectives.
- MESH :
- anatomopathologie : Récidive tumorale locale, Tumeurs de la vulve.
- effets indésirables : Lymphadénectomie.
- radiothérapie : Carcinome épidermoïde, Tumeurs de la vulve.
- secondaire : Carcinome épidermoïde.
- Adulte, Adulte d'âge moyen, Canal inguinal, Carcinome épidermoïde, Facteurs de risque, Femelle, Humains, Interventions chirurgicales de cytoréduction, Lymphadénectomie, Métastase lymphatique, Noeuds lymphatiques, Radiothérapie adjuvante, Sujet âgé, Sujet âgé de 80 ans ou plus, Survie sans rechute, Taux de survie, Tumeurs de la vulve, Études rétrospectives.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Carcinoma, Squamous Cell (radiotherapy), Carcinoma, Squamous Cell (secondary), Carcinoma, Squamous Cell (surgery), Cytoreduction Surgical Procedures, Disease-Free Survival, Female, Humans, Inguinal Canal, Lymph Node Excision (adverse effects), Lymph Node Excision (methods), Lymph Nodes (surgery), Lymphatic Metastasis, Middle Aged, Neoplasm Recurrence, Local (pathology), Radiotherapy, Adjuvant, Retrospective Studies, Risk Factors, Survival Rate, Vulvar Neoplasms (pathology), Vulvar Neoplasms (radiotherapy), Vulvar Neoplasms (surgery).
- MESH :
- adverse effects : Lymph Node Excision.
- methods : Lymph Node Excision.
- pathology : Neoplasm Recurrence, Local, Vulvar Neoplasms.
- radiotherapy : Carcinoma, Squamous Cell, Vulvar Neoplasms.
- secondary : Carcinoma, Squamous Cell.
- surgery : Carcinoma, Squamous Cell, Lymph Nodes, Vulvar Neoplasms.
- Adult, Aged, Aged, 80 and over, Cytoreduction Surgical Procedures, Disease-Free Survival, Female, Humans, Inguinal Canal, Lymphatic Metastasis, Middle Aged, Radiotherapy, Adjuvant, Retrospective Studies, Risk Factors, Survival Rate.
Abstract
Treatment of groin metastasis in vulvar squamous cell carcinoma (VSCC) patients consists of surgery, often combined with (chemo)radiotherapy, and is associated with significant morbidity. Our aim was to compare the risk of groin recurrence and morbidity in patients with lymph node positive VSCC after standard full inguinofemoral lymphadenectomy (IFL) versus less radical debulking of clinically involved lymph nodes or removal of sentinel nodes only followed by radiotherapy.
DOI: 10.1016/j.ygyno.2015.09.081
PubMed: 26432039
Affiliations:
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Nooij</name><affiliation wicri:level="3"><nlm:affiliation>Department of Gynecology, Leiden University Medical Center, Leiden, The Netherlands; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: L.S.Nooij@lumc.nl.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gynecology, Leiden University Medical Center, Leiden, The Netherlands; Department of Pathology, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Ongkiehong, Paulien J" sort="Ongkiehong, Paulien J" uniqKey="Ongkiehong P" first="Paulien J" last="Ongkiehong">Paulien J. Ongkiehong</name><affiliation wicri:level="3"><nlm:affiliation>Department of Gynecology, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gynecology, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Zwet, Erik W" sort="Van Zwet, Erik W" uniqKey="Van Zwet E" first="Erik W" last="Van Zwet">Erik W. Van Zwet</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Statistics, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Statistics, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Bosse, Tjalling" sort="Bosse, Tjalling" uniqKey="Bosse T" first="Tjalling" last="Bosse">Tjalling Bosse</name><affiliation wicri:level="3"><nlm:affiliation>Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Pathology, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Creutzberg, Carien L" sort="Creutzberg, Carien L" uniqKey="Creutzberg C" first="Carien L" last="Creutzberg">Carien L. Creutzberg</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiotherapy, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Radiotherapy, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Gaarenstroom, Katja N" sort="Gaarenstroom, Katja N" uniqKey="Gaarenstroom K" first="Katja N" last="Gaarenstroom">Katja N. Gaarenstroom</name><affiliation wicri:level="3"><nlm:affiliation>Department of Gynecology, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gynecology, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Poelgeest, Mariette I E" sort="Van Poelgeest, Mariette I E" uniqKey="Van Poelgeest M" first="Mariette I E" last="Van Poelgeest">Mariette I E. Van Poelgeest</name><affiliation wicri:level="3"><nlm:affiliation>Department of Gynecology, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gynecology, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author></analytic><series><title level="j">Gynecologic oncology</title><idno type="eISSN">1095-6859</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Carcinoma, Squamous Cell (radiotherapy)</term><term>Carcinoma, Squamous Cell (secondary)</term><term>Carcinoma, Squamous Cell (surgery)</term><term>Cytoreduction Surgical Procedures</term><term>Disease-Free Survival</term><term>Female</term><term>Humans</term><term>Inguinal Canal</term><term>Lymph Node Excision (adverse effects)</term><term>Lymph Node Excision (methods)</term><term>Lymph Nodes (surgery)</term><term>Lymphatic Metastasis</term><term>Middle Aged</term><term>Neoplasm Recurrence, Local (pathology)</term><term>Radiotherapy, Adjuvant</term><term>Retrospective Studies</term><term>Risk Factors</term><term>Survival Rate</term><term>Vulvar Neoplasms (pathology)</term><term>Vulvar Neoplasms (radiotherapy)</term><term>Vulvar Neoplasms (surgery)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Canal inguinal</term><term>Carcinome épidermoïde ()</term><term>Carcinome épidermoïde (radiothérapie)</term><term>Carcinome épidermoïde (secondaire)</term><term>Facteurs de risque</term><term>Femelle</term><term>Humains</term><term>Interventions chirurgicales de cytoréduction</term><term>Lymphadénectomie ()</term><term>Lymphadénectomie (effets indésirables)</term><term>Métastase lymphatique</term><term>Noeuds lymphatiques ()</term><term>Radiothérapie adjuvante</term><term>Récidive tumorale locale (anatomopathologie)</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Survie sans rechute</term><term>Taux de survie</term><term>Tumeurs de la vulve ()</term><term>Tumeurs de la vulve (anatomopathologie)</term><term>Tumeurs de la vulve (radiothérapie)</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Lymph Node Excision</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Récidive tumorale locale</term><term>Tumeurs de la vulve</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Lymphadénectomie</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Lymph Node Excision</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Neoplasm Recurrence, Local</term><term>Vulvar Neoplasms</term></keywords><keywords scheme="MESH" qualifier="radiotherapy" xml:lang="en"><term>Carcinoma, Squamous Cell</term><term>Vulvar Neoplasms</term></keywords><keywords scheme="MESH" qualifier="radiothérapie" xml:lang="fr"><term>Carcinome épidermoïde</term><term>Tumeurs de la vulve</term></keywords><keywords scheme="MESH" qualifier="secondaire" xml:lang="fr"><term>Carcinome épidermoïde</term></keywords><keywords scheme="MESH" qualifier="secondary" xml:lang="en"><term>Carcinoma, Squamous Cell</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Carcinoma, Squamous Cell</term><term>Lymph Nodes</term><term>Vulvar Neoplasms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Cytoreduction Surgical Procedures</term><term>Disease-Free Survival</term><term>Female</term><term>Humans</term><term>Inguinal Canal</term><term>Lymphatic Metastasis</term><term>Middle Aged</term><term>Radiotherapy, Adjuvant</term><term>Retrospective Studies</term><term>Risk Factors</term><term>Survival Rate</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Canal inguinal</term><term>Carcinome épidermoïde</term><term>Facteurs de risque</term><term>Femelle</term><term>Humains</term><term>Interventions chirurgicales de cytoréduction</term><term>Lymphadénectomie</term><term>Métastase lymphatique</term><term>Noeuds lymphatiques</term><term>Radiothérapie adjuvante</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Survie sans rechute</term><term>Taux de survie</term><term>Tumeurs de la vulve</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Treatment of groin metastasis in vulvar squamous cell carcinoma (VSCC) patients consists of surgery, often combined with (chemo)radiotherapy, and is associated with significant morbidity. Our aim was to compare the risk of groin recurrence and morbidity in patients with lymph node positive VSCC after standard full inguinofemoral lymphadenectomy (IFL) versus less radical debulking of clinically involved lymph nodes or removal of sentinel nodes only followed by radiotherapy.</div></front></TEI><affiliations><list><country><li>Pays-Bas</li></country><region><li>Hollande-Méridionale</li></region><settlement><li>Leyde</li></settlement></list><tree><country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Nooij, Linda S" sort="Nooij, Linda S" uniqKey="Nooij L" first="Linda S" last="Nooij">Linda S. Nooij</name></region><name sortKey="Bosse, Tjalling" sort="Bosse, Tjalling" uniqKey="Bosse T" first="Tjalling" last="Bosse">Tjalling Bosse</name><name sortKey="Creutzberg, Carien L" sort="Creutzberg, Carien L" uniqKey="Creutzberg C" first="Carien L" last="Creutzberg">Carien L. Creutzberg</name><name sortKey="Gaarenstroom, Katja N" sort="Gaarenstroom, Katja N" uniqKey="Gaarenstroom K" first="Katja N" last="Gaarenstroom">Katja N. Gaarenstroom</name><name sortKey="Ongkiehong, Paulien J" sort="Ongkiehong, Paulien J" uniqKey="Ongkiehong P" first="Paulien J" last="Ongkiehong">Paulien J. Ongkiehong</name><name sortKey="Van Poelgeest, Mariette I E" sort="Van Poelgeest, Mariette I E" uniqKey="Van Poelgeest M" first="Mariette I E" last="Van Poelgeest">Mariette I E. Van Poelgeest</name><name sortKey="Van Zwet, Erik W" sort="Van Zwet, Erik W" uniqKey="Van Zwet E" first="Erik W" last="Van Zwet">Erik W. Van Zwet</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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