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Penoscrotal lymphedema associated with metastatic renal cell carcinoma.

Identifieur interne : 001A04 ( Main/Exploration ); précédent : 001A03; suivant : 001A05

Penoscrotal lymphedema associated with metastatic renal cell carcinoma.

Auteurs : David Crawley [États-Unis] ; Peter Haddock ; Max Jackson ; Jeffrey Kamradt ; Stuart Kesler

Source :

RBID : pubmed:26267035

Descripteurs français

English descriptors

Abstract

A 64-year-old male presented with lower back pain, radiating in a sciatic-type distribution, swelling in his lower abdomen and right leg, and edema of the scrotum and penile shaft. A sonogram and CT imaging indicated an enhancing mass in the right kidney and a spinal metastasis. The right lower extremity and penoscrotal lymphedema was caused by lymphatic obstruction due to a sacral metastasis of renal cell carcinoma. He was treated with cytoreductive nephrectomy, radiation and a systemic tyrosine kinase inhibitor. Pelvic imaging is suggested to determine whether malignant lymphatic obstruction is present when presented with idiopathic penoscrotal edema.

PubMed: 26267035


Affiliations:


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Le document en format XML

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<nlm:affiliation>Urology Division, Hartford Healthcare Medical Group, Hartford, Connecticut, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Urology Division, Hartford Healthcare Medical Group, Hartford, Connecticut</wicri:regionArea>
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<name sortKey="Jackson, Max" sort="Jackson, Max" uniqKey="Jackson M" first="Max" last="Jackson">Max Jackson</name>
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<name sortKey="Kamradt, Jeffrey" sort="Kamradt, Jeffrey" uniqKey="Kamradt J" first="Jeffrey" last="Kamradt">Jeffrey Kamradt</name>
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<term>Carcinoma, Renal Cell (diagnostic imaging)</term>
<term>Carcinoma, Renal Cell (secondary)</term>
<term>Humans</term>
<term>Kidney Neoplasms (diagnostic imaging)</term>
<term>Kidney Neoplasms (pathology)</term>
<term>Lower Extremity</term>
<term>Lymphedema (etiology)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Penile Diseases (etiology)</term>
<term>Sacrum (diagnostic imaging)</term>
<term>Scrotum</term>
<term>Spinal Neoplasms (complications)</term>
<term>Spinal Neoplasms (diagnostic imaging)</term>
<term>Spinal Neoplasms (secondary)</term>
<term>Tomography, X-Ray Computed</term>
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<term>Adulte d'âge moyen</term>
<term>Humains</term>
<term>Lymphoedème (étiologie)</term>
<term>Maladies du pénis (étiologie)</term>
<term>Membre inférieur</term>
<term>Mâle</term>
<term>Néphrocarcinome (imagerie diagnostique)</term>
<term>Néphrocarcinome (secondaire)</term>
<term>Sacrum (imagerie diagnostique)</term>
<term>Scrotum</term>
<term>Tomodensitométrie</term>
<term>Tumeurs du rachis ()</term>
<term>Tumeurs du rachis (imagerie diagnostique)</term>
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<term>Tumeurs du rein (imagerie diagnostique)</term>
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<term>Tumeurs du rein</term>
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<term>Spinal Neoplasms</term>
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<term>Carcinoma, Renal Cell</term>
<term>Kidney Neoplasms</term>
<term>Sacrum</term>
<term>Spinal Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Lymphedema</term>
<term>Penile Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr">
<term>Néphrocarcinome</term>
<term>Sacrum</term>
<term>Tumeurs du rachis</term>
<term>Tumeurs du rein</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Kidney Neoplasms</term>
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<term>Néphrocarcinome</term>
<term>Tumeurs du rachis</term>
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<term>Carcinoma, Renal Cell</term>
<term>Spinal Neoplasms</term>
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<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr">
<term>Lymphoedème</term>
<term>Maladies du pénis</term>
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<term>Humans</term>
<term>Lower Extremity</term>
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<term>Middle Aged</term>
<term>Scrotum</term>
<term>Tomography, X-Ray Computed</term>
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<term>Humains</term>
<term>Membre inférieur</term>
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<term>Tumeurs du rachis</term>
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<front>
<div type="abstract" xml:lang="en">A 64-year-old male presented with lower back pain, radiating in a sciatic-type distribution, swelling in his lower abdomen and right leg, and edema of the scrotum and penile shaft. A sonogram and CT imaging indicated an enhancing mass in the right kidney and a spinal metastasis. The right lower extremity and penoscrotal lymphedema was caused by lymphatic obstruction due to a sacral metastasis of renal cell carcinoma. He was treated with cytoreductive nephrectomy, radiation and a systemic tyrosine kinase inhibitor. Pelvic imaging is suggested to determine whether malignant lymphatic obstruction is present when presented with idiopathic penoscrotal edema.</div>
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<name sortKey="Haddock, Peter" sort="Haddock, Peter" uniqKey="Haddock P" first="Peter" last="Haddock">Peter Haddock</name>
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<name sortKey="Kamradt, Jeffrey" sort="Kamradt, Jeffrey" uniqKey="Kamradt J" first="Jeffrey" last="Kamradt">Jeffrey Kamradt</name>
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