10-Year experience regarding the reliability and morbidity of radio guided lymph node biopsy in penile cancer patients and the associated radiation exposure of medical staff in this procedure
Identifieur interne : 001563 ( Main/Exploration ); précédent : 001562; suivant : 00156410-Year experience regarding the reliability and morbidity of radio guided lymph node biopsy in penile cancer patients and the associated radiation exposure of medical staff in this procedure
Auteurs : Ulf Lützen [Allemagne] ; Carsten Maik Naumann [Allemagne] ; Jens Dischinger [Allemagne] ; Marlies Marx [Allemagne] ; René Baumann [Allemagne] ; Yi Zhao [Allemagne] ; Michael Jüptner [Allemagne] ; Daniar Osmonov [Allemagne] ; Katrin Bothe [Allemagne] ; Klaus-Peter Jünemann [Allemagne] ; Maaz Zuhayra [Allemagne]Source :
- BMC Urology [ 1471-2490 ] ; 2016.
Abstract
The guidelines of the European Association of Urologists (EAU), of the German Society of Nuclear Medicine (DGN), and the European Society for Medical Oncology (ESMO) recommend sentinel lymph node biopsy (SLNB) for lymph node staging in penile cancer with non-palpable inguinal lymph nodes as one diagnostic method. Despite this, the method is neither widely nor regularly applied in Germany – the same applies to many other countries, which may be due to insecurity in dealing with open radioactive tracers. This study aims to assess the reliability and morbidity of this method, as well as the associated radioactive burden for clinical staff.
Between 2006 and 2016, 34 patients with an invasive penile carcinoma and inconspicuous inguinal lymph node status underwent SLNB in 57 groins after application of a radiotracer (Tc-99 m nanocolloid). We collected the results prospectively. The reliability of the method was assessed by determining the false-negative rate. In addition, we evaluated complication rates and determined the radioactive burden for the clinical staff both pre- and intraoperatively.
SLNB was performed in 34 patients with penile cancer with non-palpable inguinal lymph nodes in 57 groins. In two patients inguinal lymph node metastases were detected by means of SLNB. In one patient recurrent inguinal lymph node disease was found after negative SLNB in both groins. Thus, the false negative rate was 3.13 % per patient (1/32 patients) and 3.51 % per groin (2/57 groins). The morbidity rate was 2.94 % per patient (1/34 patients) and 1.75 % per groin (1/57 groins). Radiation exposure for the clinical staff during this procedure was low at a maximum of ca. four μSV per intervention.
SLNB is a reliable method with low morbidity that is associated with a low radiation burden for clinical staff. Due to the enhanced methodological and logistic demands, this intervention should be performed in specialized centres and in an interdisciplinary approach.
Url:
DOI: 10.1186/s12894-016-0166-2
PubMed: 27485215
PubMed Central: 4969690
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000C93
- to stream Pmc, to step Curation: 000C92
- to stream Pmc, to step Checkpoint: 000D04
- to stream Ncbi, to step Merge: 008646
- to stream Ncbi, to step Curation: 008646
- to stream Ncbi, to step Checkpoint: 008646
- to stream Main, to step Merge: 001565
- to stream Main, to step Curation: 001563
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">10-Year experience regarding the reliability and morbidity of radio guided lymph node biopsy in penile cancer patients and the associated radiation exposure of medical staff in this procedure</title><author><name sortKey="Lutzen, Ulf" sort="Lutzen, Ulf" uniqKey="Lutzen U" first="Ulf" last="Lützen">Ulf Lützen</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Naumann, Carsten Maik" sort="Naumann, Carsten Maik" uniqKey="Naumann C" first="Carsten Maik" last="Naumann">Carsten Maik Naumann</name><affiliation wicri:level="3"><nlm:aff id="Aff2">Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Dischinger, Jens" sort="Dischinger, Jens" uniqKey="Dischinger J" first="Jens" last="Dischinger">Jens Dischinger</name><affiliation wicri:level="3"><nlm:aff id="Aff3">Northern German Seminar for Radiation Protection gGmbH at the Christian-Albrechts-University Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Northern German Seminar for Radiation Protection gGmbH at the Christian-Albrechts-University Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Marx, Marlies" sort="Marx, Marlies" uniqKey="Marx M" first="Marlies" last="Marx">Marlies Marx</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Baumann, Rene" sort="Baumann, Rene" uniqKey="Baumann R" first="René" last="Baumann">René Baumann</name><affiliation wicri:level="3"><nlm:aff id="Aff4">Department of Radio Oncology, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radio Oncology, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Zhao, Yi" sort="Zhao, Yi" uniqKey="Zhao Y" first="Yi" last="Zhao">Yi Zhao</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Juptner, Michael" sort="Juptner, Michael" uniqKey="Juptner M" first="Michael" last="Jüptner">Michael Jüptner</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Osmonov, Daniar" sort="Osmonov, Daniar" uniqKey="Osmonov D" first="Daniar" last="Osmonov">Daniar Osmonov</name><affiliation wicri:level="3"><nlm:aff id="Aff2">Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Bothe, Katrin" sort="Bothe, Katrin" uniqKey="Bothe K" first="Katrin" last="Bothe">Katrin Bothe</name><affiliation wicri:level="3"><nlm:aff id="Aff2">Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Junemann, Klaus Peter" sort="Junemann, Klaus Peter" uniqKey="Junemann K" first="Klaus-Peter" last="Jünemann">Klaus-Peter Jünemann</name><affiliation wicri:level="3"><nlm:aff id="Aff2">Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Zuhayra, Maaz" sort="Zuhayra, Maaz" uniqKey="Zuhayra M" first="Maaz" last="Zuhayra">Maaz Zuhayra</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27485215</idno><idno type="pmc">4969690</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969690</idno><idno type="RBID">PMC:4969690</idno><idno type="doi">10.1186/s12894-016-0166-2</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000C93</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000C93</idno><idno type="wicri:Area/Pmc/Curation">000C92</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000C92</idno><idno type="wicri:Area/Pmc/Checkpoint">000D04</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000D04</idno><idno type="wicri:Area/Ncbi/Merge">008646</idno><idno type="wicri:Area/Ncbi/Curation">008646</idno><idno type="wicri:Area/Ncbi/Checkpoint">008646</idno><idno type="wicri:Area/Main/Merge">001565</idno><idno type="wicri:Area/Main/Curation">001563</idno><idno type="wicri:Area/Main/Exploration">001563</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">10-Year experience regarding the reliability and morbidity of radio guided lymph node biopsy in penile cancer patients and the associated radiation exposure of medical staff in this procedure</title><author><name sortKey="Lutzen, Ulf" sort="Lutzen, Ulf" uniqKey="Lutzen U" first="Ulf" last="Lützen">Ulf Lützen</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Naumann, Carsten Maik" sort="Naumann, Carsten Maik" uniqKey="Naumann C" first="Carsten Maik" last="Naumann">Carsten Maik Naumann</name><affiliation wicri:level="3"><nlm:aff id="Aff2">Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Dischinger, Jens" sort="Dischinger, Jens" uniqKey="Dischinger J" first="Jens" last="Dischinger">Jens Dischinger</name><affiliation wicri:level="3"><nlm:aff id="Aff3">Northern German Seminar for Radiation Protection gGmbH at the Christian-Albrechts-University Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Northern German Seminar for Radiation Protection gGmbH at the Christian-Albrechts-University Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Marx, Marlies" sort="Marx, Marlies" uniqKey="Marx M" first="Marlies" last="Marx">Marlies Marx</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Baumann, Rene" sort="Baumann, Rene" uniqKey="Baumann R" first="René" last="Baumann">René Baumann</name><affiliation wicri:level="3"><nlm:aff id="Aff4">Department of Radio Oncology, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radio Oncology, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Zhao, Yi" sort="Zhao, Yi" uniqKey="Zhao Y" first="Yi" last="Zhao">Yi Zhao</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Juptner, Michael" sort="Juptner, Michael" uniqKey="Juptner M" first="Michael" last="Jüptner">Michael Jüptner</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Osmonov, Daniar" sort="Osmonov, Daniar" uniqKey="Osmonov D" first="Daniar" last="Osmonov">Daniar Osmonov</name><affiliation wicri:level="3"><nlm:aff id="Aff2">Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Bothe, Katrin" sort="Bothe, Katrin" uniqKey="Bothe K" first="Katrin" last="Bothe">Katrin Bothe</name><affiliation wicri:level="3"><nlm:aff id="Aff2">Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Junemann, Klaus Peter" sort="Junemann, Klaus Peter" uniqKey="Junemann K" first="Klaus-Peter" last="Jünemann">Klaus-Peter Jünemann</name><affiliation wicri:level="3"><nlm:aff id="Aff2">Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Zuhayra, Maaz" sort="Zuhayra, Maaz" uniqKey="Zuhayra M" first="Maaz" last="Zuhayra">Maaz Zuhayra</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nuclear medicine, Molecular Imaging Diagnostics and Therapy, University Hospital Schleswig Holstein, Campus Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author></analytic><series><title level="j">BMC Urology</title><idno type="eISSN">1471-2490</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>The guidelines of the European Association of Urologists (EAU), of the German Society of Nuclear Medicine (DGN), and the European Society for Medical Oncology (ESMO) recommend sentinel lymph node biopsy (SLNB) for lymph node staging in penile cancer with non-palpable inguinal lymph nodes as one diagnostic method. Despite this, the method is neither widely nor regularly applied in Germany – the same applies to many other countries, which may be due to insecurity in dealing with open radioactive tracers. This study aims to assess the reliability and morbidity of this method, as well as the associated radioactive burden for clinical staff.</p></sec><sec><title>Methods</title><p>Between 2006 and 2016, 34 patients with an invasive penile carcinoma and inconspicuous inguinal lymph node status underwent SLNB in 57 groins after application of a radiotracer (Tc-99 m nanocolloid). We collected the results prospectively. The reliability of the method was assessed by determining the false-negative rate. In addition, we evaluated complication rates and determined the radioactive burden for the clinical staff both pre- and intraoperatively.</p></sec><sec><title>Results</title><p>SLNB was performed in 34 patients with penile cancer with non-palpable inguinal lymph nodes in 57 groins. In two patients inguinal lymph node metastases were detected by means of SLNB. In one patient recurrent inguinal lymph node disease was found after negative SLNB in both groins. Thus, the false negative rate was 3.13 % per patient (1/32 patients) and 3.51 % per groin (2/57 groins). The morbidity rate was 2.94 % per patient (1/34 patients) and 1.75 % per groin (1/57 groins). Radiation exposure for the clinical staff during this procedure was low at a maximum of ca. four μSV per intervention.</p></sec><sec><title>Conclusions</title><p>SLNB is a reliable method with low morbidity that is associated with a low radiation burden for clinical staff. Due to the enhanced methodological and logistic demands, this intervention should be performed in specialized centres and in an interdisciplinary approach.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Hakenberg, Ow" uniqKey="Hakenberg O">OW Hakenberg</name></author><author><name sortKey="Comperat, Em" uniqKey="Comperat E">EM Compérat</name></author><author><name sortKey="Minhas, S" uniqKey="Minhas S">S Minhas</name></author><author><name sortKey="Necchi, A" uniqKey="Necchi A">A Necchi</name></author><author><name sortKey="Protzel, C" uniqKey="Protzel C">C Protzel</name></author><author><name sortKey="Watkin, N" uniqKey="Watkin N">N Watkin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vogt, H" uniqKey="Vogt H">H Vogt</name></author><author><name sortKey="Schmidt, M" uniqKey="Schmidt M">M Schmidt</name></author><author><name sortKey="Bares, R" uniqKey="Bares R">R Bares</name></author><author><name sortKey="Brenner, W" uniqKey="Brenner W">W Brenner</name></author><author><name sortKey="Grunwald, F" uniqKey="Grunwald F">F Grünwald</name></author><author><name sortKey="Kopp, J" uniqKey="Kopp J">J Kopp</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Poppel, Hv" uniqKey="Poppel H">HV Poppel</name></author><author><name sortKey="Watkin, Na" uniqKey="Watkin N">NA Watkin</name></author><author><name sortKey="Osanto, S" uniqKey="Osanto S">S Osanto</name></author><author><name sortKey="Moonen, L" uniqKey="Moonen L">L Moonen</name></author><author><name sortKey="Horwich, A" uniqKey="Horwich A">A Horwich</name></author><author><name sortKey="Kataja, V" uniqKey="Kataja V">V Kataja</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pizzocaro, G" uniqKey="Pizzocaro G">G Pizzocaro</name></author><author><name sortKey="Algaba, F" uniqKey="Algaba F">F Algaba</name></author><author><name sortKey="Horenblas, S" uniqKey="Horenblas S">S Horenblas</name></author><author><name sortKey="Solsona, E" uniqKey="Solsona E">E Solsona</name></author><author><name sortKey="Tana, S" uniqKey="Tana S">S Tana</name></author><author><name sortKey="Van Der Poel, H" uniqKey="Van Der Poel H">H Van Der Poel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kirrander, P" uniqKey="Kirrander P">P Kirrander</name></author><author><name sortKey="Andren, O" uniqKey="Andren O">O Andrén</name></author><author><name sortKey="Windahl, T" uniqKey="Windahl T">T Windahl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leijte, Jap" uniqKey="Leijte J">JAP Leijte</name></author><author><name sortKey="Hughes, B" uniqKey="Hughes B">B Hughes</name></author><author><name sortKey="Graafland, Nm" uniqKey="Graafland N">NM Graafland</name></author><author><name sortKey="Kroon, Bk" uniqKey="Kroon B">BK Kroon</name></author><author><name sortKey="Olmos, Rav" uniqKey="Olmos R">RAV Olmos</name></author><author><name sortKey="Nieweg, Oe" uniqKey="Nieweg O">OE Nieweg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kroon, Bk" uniqKey="Kroon B">BK Kroon</name></author><author><name sortKey="Horenblas, S" uniqKey="Horenblas S">S Horenblas</name></author><author><name sortKey="Lont, Ap" uniqKey="Lont A">AP Lont</name></author><author><name sortKey="Tanis, Pj" uniqKey="Tanis P">PJ Tanis</name></author><author><name sortKey="Gallee, Mpw" uniqKey="Gallee M">MPW Gallee</name></author><author><name sortKey="Nieweg, Oe" uniqKey="Nieweg O">OE Nieweg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bevan Thomas, R" uniqKey="Bevan Thomas R">R Bevan-Thomas</name></author><author><name sortKey="Slaton, Jw" uniqKey="Slaton J">JW Slaton</name></author><author><name sortKey="Pettaway, Ca" uniqKey="Pettaway C">CA Pettaway</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcdougal, Ws" uniqKey="Mcdougal W">WS McDougal</name></author><author><name sortKey="Kirchner, Fk" uniqKey="Kirchner F">FK Kirchner</name></author><author><name sortKey="Edwards, Rh" uniqKey="Edwards R">RH Edwards</name></author><author><name sortKey="Killion, Lt" uniqKey="Killion L">LT Killion</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Heyns, Cf" uniqKey="Heyns C">CF Heyns</name></author><author><name sortKey="Fleshner, N" uniqKey="Fleshner N">N Fleshner</name></author><author><name sortKey="Sangar, V" uniqKey="Sangar V">V Sangar</name></author><author><name sortKey="Schlenker, B" uniqKey="Schlenker B">B Schlenker</name></author><author><name sortKey="Yuvaraja, Tb" uniqKey="Yuvaraja T">TB Yuvaraja</name></author><author><name sortKey="Van Poppel, H" uniqKey="Van Poppel H">H van Poppel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kochhar, R" uniqKey="Kochhar R">R Kochhar</name></author><author><name sortKey="Taylor, B" uniqKey="Taylor B">B Taylor</name></author><author><name sortKey="Sangar, V" uniqKey="Sangar V">V Sangar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hughes, B" uniqKey="Hughes B">B Hughes</name></author><author><name sortKey="Leijte, J" uniqKey="Leijte J">J Leijte</name></author><author><name sortKey="Shabbir, M" uniqKey="Shabbir M">M Shabbir</name></author><author><name sortKey="Watkin, N" uniqKey="Watkin N">N Watkin</name></author><author><name sortKey="Horenblas, S" uniqKey="Horenblas S">S Horenblas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mueller Lisse, Ug" uniqKey="Mueller Lisse U">UG Mueller-Lisse</name></author><author><name sortKey="Scher, B" uniqKey="Scher B">B Scher</name></author><author><name sortKey="Scherr, Mk" uniqKey="Scherr M">MK Scherr</name></author><author><name sortKey="Seitz, M" uniqKey="Seitz M">M Seitz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kroon, Bk" uniqKey="Kroon B">BK Kroon</name></author><author><name sortKey="Horenblas, S" uniqKey="Horenblas S">S Horenblas</name></author><author><name sortKey="Deurloo, Ee" uniqKey="Deurloo E">EE Deurloo</name></author><author><name sortKey="Nieweg, Oe" uniqKey="Nieweg O">OE Nieweg</name></author><author><name sortKey="Teertstra, Hj" uniqKey="Teertstra H">HJ Teertstra</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Naumann, Cm" uniqKey="Naumann C">CM Naumann</name></author><author><name sortKey="Alkatout, I" uniqKey="Alkatout I">I Alkatout</name></author><author><name sortKey="Hamann, Mf" uniqKey="Hamann M">MF Hamann</name></author><author><name sortKey="Al Najar, A" uniqKey="Al Najar A">A Al-Najar</name></author><author><name sortKey="Hegele, A" uniqKey="Hegele A">A Hegele</name></author><author><name sortKey="Korda, Jb" uniqKey="Korda J">JB Korda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gunia, S" uniqKey="Gunia S">S Gunia</name></author><author><name sortKey="Burger, M" uniqKey="Burger M">M Burger</name></author><author><name sortKey="Hakenberg, Ow" uniqKey="Hakenberg O">OW Hakenberg</name></author><author><name sortKey="May, D" uniqKey="May D">D May</name></author><author><name sortKey="Koch, S" uniqKey="Koch S">S Koch</name></author><author><name sortKey="Jain, A" uniqKey="Jain A">A Jain</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lam, W" uniqKey="Lam W">W Lam</name></author><author><name sortKey="Alnajjar, Hm" uniqKey="Alnajjar H">HM Alnajjar</name></author><author><name sortKey="La Touche, S" uniqKey="La Touche S">S La-Touche</name></author><author><name sortKey="Perry, M" uniqKey="Perry M">M Perry</name></author><author><name sortKey="Sharma, D" uniqKey="Sharma D">D Sharma</name></author><author><name sortKey="Corbishley, C" uniqKey="Corbishley C">C Corbishley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kroon, Bk" uniqKey="Kroon B">BK Kroon</name></author><author><name sortKey="Horenblas, S" uniqKey="Horenblas S">S Horenblas</name></author><author><name sortKey="Meinhardt, W" uniqKey="Meinhardt W">W Meinhardt</name></author><author><name sortKey="Van Der Poel, Hg" uniqKey="Van Der Poel H">HG van der Poel</name></author><author><name sortKey="Bex, A" uniqKey="Bex A">A Bex</name></author><author><name sortKey="Van Tinteren, H" uniqKey="Van Tinteren H">H van Tinteren</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Solsona, E" uniqKey="Solsona E">E Solsona</name></author><author><name sortKey="Algaba, F" uniqKey="Algaba F">F Algaba</name></author><author><name sortKey="Horenblas, S" uniqKey="Horenblas S">S Horenblas</name></author><author><name sortKey="Pizzocaro, G" uniqKey="Pizzocaro G">G Pizzocaro</name></author><author><name sortKey="Windahl, T" uniqKey="Windahl T">T Windahl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Graafland, Nm" uniqKey="Graafland N">NM Graafland</name></author><author><name sortKey="Valdes Olmos, Ra" uniqKey="Valdes Olmos R">RA Valdés Olmos</name></author><author><name sortKey="Meinhardt, W" uniqKey="Meinhardt W">W Meinhardt</name></author><author><name sortKey="Bex, A" uniqKey="Bex A">A Bex</name></author><author><name sortKey="Van Der Poel, Hg" uniqKey="Van Der Poel H">HG van der Poel</name></author><author><name sortKey="Van Boven, Hh" uniqKey="Van Boven H">HH van Boven</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kroon, Bk" uniqKey="Kroon B">BK Kroon</name></author><author><name sortKey="Horenblas, S" uniqKey="Horenblas S">S Horenblas</name></author><author><name sortKey="Estourgie, Sh" uniqKey="Estourgie S">SH Estourgie</name></author><author><name sortKey="Lont, Ap" uniqKey="Lont A">AP Lont</name></author><author><name sortKey="Valdes Olmos, Ra" uniqKey="Valdes Olmos R">RA Valdés Olmos</name></author><author><name sortKey="Nieweg, Oe" uniqKey="Nieweg O">OE Nieweg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Neto, As" uniqKey="Neto A">AS Neto</name></author><author><name sortKey="Tobias Machado, M" uniqKey="Tobias Machado M">M Tobias-Machado</name></author><author><name sortKey="Ficarra, V" uniqKey="Ficarra V">V Ficarra</name></author><author><name sortKey="Wroclawski, Ml" uniqKey="Wroclawski M">ML Wroclawski</name></author><author><name sortKey="Amarante, Rdm" uniqKey="Amarante R">RDM Amarante</name></author><author><name sortKey="Pompeo, Acl" uniqKey="Pompeo A">ACL Pompeo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leijte, Jap" uniqKey="Leijte J">JAP Leijte</name></author><author><name sortKey="Van Der Ploeg, Imc" uniqKey="Van Der Ploeg I">IMC van der Ploeg</name></author><author><name sortKey="Valdes Olmos, Ra" uniqKey="Valdes Olmos R">RA Valdés Olmos</name></author><author><name sortKey="Nieweg, Oe" uniqKey="Nieweg O">OE Nieweg</name></author><author><name sortKey="Horenblas, S" uniqKey="Horenblas S">S Horenblas</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Siegel, Rl" uniqKey="Siegel R">RL Siegel</name></author><author><name sortKey="Miller, Kd" uniqKey="Miller K">KD Miller</name></author><author><name sortKey="Jemal, A" uniqKey="Jemal A">A Jemal</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>Schleswig-Holstein</li></region><settlement><li>Kiel</li></settlement></list><tree><country name="Allemagne"><region name="Schleswig-Holstein"><name sortKey="Lutzen, Ulf" sort="Lutzen, Ulf" uniqKey="Lutzen U" first="Ulf" last="Lützen">Ulf Lützen</name></region><name sortKey="Baumann, Rene" sort="Baumann, Rene" uniqKey="Baumann R" first="René" last="Baumann">René Baumann</name><name sortKey="Bothe, Katrin" sort="Bothe, Katrin" uniqKey="Bothe K" first="Katrin" last="Bothe">Katrin Bothe</name><name sortKey="Dischinger, Jens" sort="Dischinger, Jens" uniqKey="Dischinger J" first="Jens" last="Dischinger">Jens Dischinger</name><name sortKey="Junemann, Klaus Peter" sort="Junemann, Klaus Peter" uniqKey="Junemann K" first="Klaus-Peter" last="Jünemann">Klaus-Peter Jünemann</name><name sortKey="Juptner, Michael" sort="Juptner, Michael" uniqKey="Juptner M" first="Michael" last="Jüptner">Michael Jüptner</name><name sortKey="Marx, Marlies" sort="Marx, Marlies" uniqKey="Marx M" first="Marlies" last="Marx">Marlies Marx</name><name sortKey="Naumann, Carsten Maik" sort="Naumann, Carsten Maik" uniqKey="Naumann C" first="Carsten Maik" last="Naumann">Carsten Maik Naumann</name><name sortKey="Osmonov, Daniar" sort="Osmonov, Daniar" uniqKey="Osmonov D" first="Daniar" last="Osmonov">Daniar Osmonov</name><name sortKey="Zhao, Yi" sort="Zhao, Yi" uniqKey="Zhao Y" first="Yi" last="Zhao">Yi Zhao</name><name sortKey="Zuhayra, Maaz" sort="Zuhayra, Maaz" uniqKey="Zuhayra M" first="Maaz" last="Zuhayra">Maaz Zuhayra</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001563 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001563 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:4969690
|texte= 10-Year experience regarding the reliability and morbidity of radio guided lymph node biopsy in penile cancer patients and the associated radiation exposure of medical staff in this procedure
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:27485215" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |