Constitutively Enhanced Lymphatic Pumping in the Upper Limbs of Women Who Later Develop Breast Cancer-Related Lymphedema.
Identifieur interne : 001242 ( Main/Exploration ); précédent : 001241; suivant : 001243Constitutively Enhanced Lymphatic Pumping in the Upper Limbs of Women Who Later Develop Breast Cancer-Related Lymphedema.
Auteurs : Viviana Cintolesi [Royaume-Uni] ; Anthony W B. Stanton [Royaume-Uni] ; Salena K. Bains [Royaume-Uni] ; Emma Cousins [Royaume-Uni] ; A Michael Peters [Royaume-Uni] ; Arnie D. Purushotham [Royaume-Uni] ; J Rodney Levick [Royaume-Uni] ; Peter S. Mortimer [Royaume-Uni]Source :
- Lymphatic research and biology [ 1557-8585 ] ; 2016.
Abstract
It has previously been shown that the lymph drainage rate in both upper limbs is greater in women destined to develop breast cancer-related lymphedema (BCRL) than in those who do not develop BCRL, indicating a constitutive predisposition. We explored constitutive differences further by measuring the maximum lymphatic pump pressure (Ppump) and the rate of (99m)Tc-Nanocoll transport generated by the contractile upper limb lymphatics before and after breast cancer surgery in a group of women who were followed for 2 years to determine their eventual BCRL or non-BCRL status.
DOI: 10.1089/lrb.2016.0005
PubMed: 27309032
Affiliations:
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<front><div type="abstract" xml:lang="en">It has previously been shown that the lymph drainage rate in both upper limbs is greater in women destined to develop breast cancer-related lymphedema (BCRL) than in those who do not develop BCRL, indicating a constitutive predisposition. We explored constitutive differences further by measuring the maximum lymphatic pump pressure (Ppump) and the rate of (99m)Tc-Nanocoll transport generated by the contractile upper limb lymphatics before and after breast cancer surgery in a group of women who were followed for 2 years to determine their eventual BCRL or non-BCRL status.</div>
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