Genetic Causes of Human NK Cell Deficiency and Their Effect on NK Cell Subsets
Identifieur interne : 001042 ( Main/Exploration ); précédent : 001041; suivant : 001043Genetic Causes of Human NK Cell Deficiency and Their Effect on NK Cell Subsets
Auteurs : Emily M. Mace [États-Unis] ; Jordan S. Orange [États-Unis]Source :
- Frontiers in Immunology [ 1664-3224 ] ; 2016.
Abstract
Human NK cells play critical roles in human host defense, particularly the control of viral infection and malignancy, and patients with congenital immunodeficiency affecting NK cell function or number can suffer from severe illness. The importance of NK cell function is particularly underscored in patients with primary immunodeficiency in which NK cells are the primary or sole affected population (NK cell deficiency, NKD). While NKD may lead to the absence of NK cells, we are also gaining an increasing appreciation of the effect that NKD may have on the generation of specific NK cell subsets. In turn, this leads to improved insights into the requirements for human NK cell subset generation, as well as their importance in immune homeostasis. The presence of inherently abnormally developed or functionally impaired NK cells, in particular, appears to be problematic in the way of interfering with normal human host defense and may be more impactful than low numbers of NK cells alone. Here, we review the known genetic causes of NKD and the insight that is derived by these into the requirements for human subset generation and, by extension, for NK cell-mediated immunity.
Url:
DOI: 10.3389/fimmu.2016.00545
PubMed: 27994588
PubMed Central: 5133264
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Genetic Causes of Human NK Cell Deficiency and Their Effect on NK Cell Subsets</title><author><name sortKey="Mace, Emily M" sort="Mace, Emily M" uniqKey="Mace E" first="Emily M." last="Mace">Emily M. Mace</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Center for Human Immunobiology, Baylor College of Medicine and Texas Children’s Hospital</institution>,<addr-line>Houston, TX</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Orange, Jordan S" sort="Orange, Jordan S" uniqKey="Orange J" first="Jordan S." last="Orange">Jordan S. Orange</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Center for Human Immunobiology, Baylor College of Medicine and Texas Children’s Hospital</institution>,<addr-line>Houston, TX</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27994588</idno><idno type="pmc">5133264</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133264</idno><idno type="RBID">PMC:5133264</idno><idno type="doi">10.3389/fimmu.2016.00545</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">004999</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">004999</idno><idno type="wicri:Area/Pmc/Curation">004998</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">004998</idno><idno type="wicri:Area/Pmc/Checkpoint">000941</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000941</idno><idno type="wicri:Area/Ncbi/Merge">008B34</idno><idno type="wicri:Area/Ncbi/Curation">008B34</idno><idno type="wicri:Area/Ncbi/Checkpoint">008B34</idno><idno type="wicri:Area/Main/Merge">001044</idno><idno type="wicri:Area/Main/Curation">001042</idno><idno type="wicri:Area/Main/Exploration">001042</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Genetic Causes of Human NK Cell Deficiency and Their Effect on NK Cell Subsets</title><author><name sortKey="Mace, Emily M" sort="Mace, Emily M" uniqKey="Mace E" first="Emily M." last="Mace">Emily M. Mace</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Center for Human Immunobiology, Baylor College of Medicine and Texas Children’s Hospital</institution>,<addr-line>Houston, TX</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Orange, Jordan S" sort="Orange, Jordan S" uniqKey="Orange J" first="Jordan S." last="Orange">Jordan S. Orange</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Center for Human Immunobiology, Baylor College of Medicine and Texas Children’s Hospital</institution>,<addr-line>Houston, TX</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Frontiers in Immunology</title><idno type="eISSN">1664-3224</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Human NK cells play critical roles in human host defense, particularly the control of viral infection and malignancy, and patients with congenital immunodeficiency affecting NK cell function or number can suffer from severe illness. The importance of NK cell function is particularly underscored in patients with primary immunodeficiency in which NK cells are the primary or sole affected population (NK cell deficiency, NKD). While NKD may lead to the absence of NK cells, we are also gaining an increasing appreciation of the effect that NKD may have on the generation of specific NK cell subsets. In turn, this leads to improved insights into the requirements for human NK cell subset generation, as well as their importance in immune homeostasis. The presence of inherently abnormally developed or functionally impaired NK cells, in particular, appears to be problematic in the way of interfering with normal human host defense and may be more impactful than low numbers of NK cells alone. Here, we review the known genetic causes of NKD and the insight that is derived by these into the requirements for human subset generation and, by extension, for NK cell-mediated immunity.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Ham, H" uniqKey="Ham H">H Ham</name></author><author><name sortKey="Billadeau, Dd" uniqKey="Billadeau D">DD Billadeau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Orange, Js" uniqKey="Orange J">JS Orange</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Orange, Js" uniqKey="Orange J">JS Orange</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Voss, M" uniqKey="Voss M">M Voss</name></author><author><name sortKey="Bryceson, Yt" uniqKey="Bryceson Y">YT Bryceson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Angelo, Ls" uniqKey="Angelo L">LS Angelo</name></author><author><name sortKey="Banerjee, Pp" uniqKey="Banerjee P">PP Banerjee</name></author><author><name sortKey="Monaco Shawver, L" uniqKey="Monaco Shawver L">L Monaco-Shawver</name></author><author><name sortKey="Rosen, Jb" uniqKey="Rosen J">JB Rosen</name></author><author><name sortKey="Makedonas, G" uniqKey="Makedonas G">G Makedonas</name></author><author><name sortKey="Forbes, Lr" uniqKey="Forbes L">LR Forbes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Maria, A" uniqKey="De Maria A">A De Maria</name></author><author><name sortKey="Bozzano, F" uniqKey="Bozzano F">F Bozzano</name></author><author><name sortKey="Cantoni, C" uniqKey="Cantoni C">C Cantoni</name></author><author><name sortKey="Moretta, L" uniqKey="Moretta L">L Moretta</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nielsen, N" uniqKey="Nielsen N">N Nielsen</name></author><author><name sortKey=" Dum, N" uniqKey=" Dum N">N Ødum</name></author><author><name sortKey="Urs, B" uniqKey="Urs B">B Ursø</name></author><author><name sortKey="Lanier, Ll" uniqKey="Lanier L">LL Lanier</name></author><author><name sortKey="Spee, P" uniqKey="Spee P">P Spee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gonzalez, Vd" uniqKey="Gonzalez V">VD Gonzalez</name></author><author><name sortKey="Falconer, K" uniqKey="Falconer K">K Falconer</name></author><author><name sortKey="Bjorkstrom, Nk" uniqKey="Bjorkstrom N">NK Björkström</name></author><author><name sortKey="Blom, Kg" uniqKey="Blom K">KG Blom</name></author><author><name sortKey="Weiland, O" uniqKey="Weiland O">O Weiland</name></author><author><name sortKey="Ljunggren, Hg" uniqKey="Ljunggren H">HG Ljunggren</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hu, Pf" uniqKey="Hu P">PF Hu</name></author><author><name sortKey="Hultin, Le" uniqKey="Hultin L">LE Hultin</name></author><author><name sortKey="Hultin, P" uniqKey="Hultin P">P Hultin</name></author><author><name sortKey="Hausner, Ma" uniqKey="Hausner M">MA Hausner</name></author><author><name sortKey="Hirji, K" uniqKey="Hirji K">K Hirji</name></author><author><name sortKey="Jewett, A" uniqKey="Jewett A">A Jewett</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bjorkstrom, Nk" uniqKey="Bjorkstrom N">NK Bjorkstrom</name></author><author><name sortKey="Ljunggren, Hg" uniqKey="Ljunggren H">HG Ljunggren</name></author><author><name sortKey="Sandberg, Jk" uniqKey="Sandberg J">JK Sandberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Foley, B" uniqKey="Foley B">B Foley</name></author><author><name sortKey="Cooley, S" uniqKey="Cooley S">S Cooley</name></author><author><name sortKey="Verneris, Mr" uniqKey="Verneris M">MR Verneris</name></author><author><name sortKey="Pitt, M" uniqKey="Pitt M">M Pitt</name></author><author><name sortKey="Curtsinger, J" uniqKey="Curtsinger J">J Curtsinger</name></author><author><name sortKey="Luo, X" uniqKey="Luo X">X Luo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guma, M" uniqKey="Guma M">M Gumá</name></author><author><name sortKey="Angulo, A" uniqKey="Angulo A">A Angulo</name></author><author><name sortKey="Vilches, C" uniqKey="Vilches C">C Vilches</name></author><author><name sortKey="G Mez Lozano, N" uniqKey="G Mez Lozano N">N Gómez-Lozano</name></author><author><name sortKey="Malats, N" uniqKey="Malats N">N Malats</name></author><author><name sortKey="L Pez Botet, M" uniqKey="L Pez Botet M">M López-Botet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guma, M" uniqKey="Guma M">M Gumá</name></author><author><name sortKey="Budt, M" uniqKey="Budt M">M Budt</name></author><author><name sortKey="Saez, A" uniqKey="Saez A">A Sáez</name></author><author><name sortKey="Brckalo, T" uniqKey="Brckalo T">T Brckalo</name></author><author><name sortKey="Hengel, H" uniqKey="Hengel H">H Hengel</name></author><author><name sortKey="Angulo, A" uniqKey="Angulo A">A Angulo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bjorkstrom, Nk" uniqKey="Bjorkstrom N">NK Björkström</name></author><author><name sortKey="Lindgren, T" uniqKey="Lindgren T">T Lindgren</name></author><author><name sortKey="Stoltz, M" uniqKey="Stoltz M">M Stoltz</name></author><author><name sortKey="Fauriat, C" uniqKey="Fauriat C">C Fauriat</name></author><author><name sortKey="Braun, M" uniqKey="Braun M">M Braun</name></author><author><name sortKey="Evander, M" uniqKey="Evander M">M Evander</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goodier, Mr" uniqKey="Goodier M">MR Goodier</name></author><author><name sortKey="Mela, Cm" uniqKey="Mela C">CM Mela</name></author><author><name sortKey="Steel, A" uniqKey="Steel A">A Steel</name></author><author><name sortKey="Gazzard, B" uniqKey="Gazzard B">B Gazzard</name></author><author><name sortKey="Bower, M" uniqKey="Bower M">M Bower</name></author><author><name sortKey="Gotch, F" uniqKey="Gotch F">F Gotch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brunetta, E" uniqKey="Brunetta E">E Brunetta</name></author><author><name sortKey="Fogli, M" uniqKey="Fogli M">M Fogli</name></author><author><name sortKey="Varchetta, S" uniqKey="Varchetta S">S Varchetta</name></author><author><name sortKey="Bozzo, L" uniqKey="Bozzo L">L Bozzo</name></author><author><name sortKey="Hudspeth, Kl" uniqKey="Hudspeth K">KL Hudspeth</name></author><author><name sortKey="Marcenaro, E" uniqKey="Marcenaro E">E Marcenaro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sohlberg, E" uniqKey="Sohlberg E">E Sohlberg</name></author><author><name sortKey="Saghafian Hedengren, S" uniqKey="Saghafian Hedengren S">S Saghafian-Hedengren</name></author><author><name sortKey="Rasul, E" uniqKey="Rasul E">E Rasul</name></author><author><name sortKey="Marchini, G" uniqKey="Marchini G">G Marchini</name></author><author><name sortKey="Nilsson, C" uniqKey="Nilsson C">C Nilsson</name></author><author><name sortKey="Klein, E" uniqKey="Klein E">E Klein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Beziat, V" uniqKey="Beziat V">V Béziat</name></author><author><name sortKey="Dalgard, O" uniqKey="Dalgard O">O Dalgard</name></author><author><name sortKey="Asselah, T" uniqKey="Asselah T">T Asselah</name></author><author><name sortKey="Halfon, P" uniqKey="Halfon P">P Halfon</name></author><author><name sortKey="Bedossa, P" uniqKey="Bedossa P">P Bedossa</name></author><author><name sortKey="Boudifa, A" uniqKey="Boudifa A">A Boudifa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Petitdemange, C" uniqKey="Petitdemange C">C Petitdemange</name></author><author><name sortKey="Becquart, P" uniqKey="Becquart P">P Becquart</name></author><author><name sortKey="Wauquier, N" uniqKey="Wauquier N">N Wauquier</name></author><author><name sortKey="Beziat, V" uniqKey="Beziat V">V Béziat</name></author><author><name sortKey="Debre, P" uniqKey="Debre P">P Debré</name></author><author><name sortKey="Leroy, Em" uniqKey="Leroy E">EM Leroy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, J" uniqKey="Lee J">J Lee</name></author><author><name sortKey="Zhang, T" uniqKey="Zhang T">T Zhang</name></author><author><name sortKey="Hwang, I" uniqKey="Hwang I">I Hwang</name></author><author><name sortKey="Kim, A" uniqKey="Kim A">A Kim</name></author><author><name sortKey="Nitschke, L" uniqKey="Nitschke L">L Nitschke</name></author><author><name sortKey="Kim, M" uniqKey="Kim M">M Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, T" uniqKey="Zhang T">T Zhang</name></author><author><name sortKey="Scott, Jm" uniqKey="Scott J">JM Scott</name></author><author><name sortKey="Hwang, I" uniqKey="Hwang I">I Hwang</name></author><author><name sortKey="Kim, S" uniqKey="Kim S">S Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schlums, H" uniqKey="Schlums H">H Schlums</name></author><author><name sortKey="Cichocki, F" uniqKey="Cichocki F">F Cichocki</name></author><author><name sortKey="Tesi, B" uniqKey="Tesi B">B Tesi</name></author><author><name sortKey="Theorell, J" uniqKey="Theorell J">J Theorell</name></author><author><name sortKey="Beziat, V" uniqKey="Beziat V">V Beziat</name></author><author><name sortKey="Holmes, Td" uniqKey="Holmes T">TD Holmes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Horowitz, A" uniqKey="Horowitz A">A Horowitz</name></author><author><name sortKey="Strauss Albee, Dm" uniqKey="Strauss Albee D">DM Strauss-Albee</name></author><author><name sortKey="Leipold, M" uniqKey="Leipold M">M Leipold</name></author><author><name sortKey="Kubo, J" uniqKey="Kubo J">J Kubo</name></author><author><name sortKey="Nemat Gorgani, N" uniqKey="Nemat Gorgani N">N Nemat-Gorgani</name></author><author><name sortKey="Dogan, Oc" uniqKey="Dogan O">OC Dogan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Strauss Albee, Dm" uniqKey="Strauss Albee D">DM Strauss-Albee</name></author><author><name sortKey="Fukuyama, J" uniqKey="Fukuyama J">J Fukuyama</name></author><author><name sortKey="Liang, Ec" uniqKey="Liang E">EC Liang</name></author><author><name sortKey="Yao, Y" uniqKey="Yao Y">Y Yao</name></author><author><name sortKey="Jarrell, Ja" uniqKey="Jarrell J">JA Jarrell</name></author><author><name sortKey="Drake, Al" uniqKey="Drake A">AL Drake</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Romagnani, C" uniqKey="Romagnani C">C Romagnani</name></author><author><name sortKey="Juelke, K" uniqKey="Juelke K">K Juelke</name></author><author><name sortKey="Falco, M" uniqKey="Falco M">M Falco</name></author><author><name sortKey="Morandi, B" uniqKey="Morandi B">B Morandi</name></author><author><name sortKey="D Gostino, A" uniqKey="D Gostino A">A D’Agostino</name></author><author><name sortKey="Costa, R" uniqKey="Costa R">R Costa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dulphy, N" uniqKey="Dulphy N">N Dulphy</name></author><author><name sortKey="Haas, P" uniqKey="Haas P">P Haas</name></author><author><name sortKey="Busson, M" uniqKey="Busson M">M Busson</name></author><author><name sortKey="Belhadj, S" uniqKey="Belhadj S">S Belhadj</name></author><author><name sortKey="Peffault De Latour, R" uniqKey="Peffault De Latour R">R Peffault de Latour</name></author><author><name sortKey="Robin, M" uniqKey="Robin M">M Robin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chan, A" uniqKey="Chan A">A Chan</name></author><author><name sortKey="Hong, Dl" uniqKey="Hong D">DL Hong</name></author><author><name sortKey="Atzberger, A" uniqKey="Atzberger A">A Atzberger</name></author><author><name sortKey="Kollnberger, S" uniqKey="Kollnberger S">S Kollnberger</name></author><author><name sortKey="Filer, Ad" uniqKey="Filer A">AD Filer</name></author><author><name sortKey="Buckley, Cd" uniqKey="Buckley C">CD Buckley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cooley, S" uniqKey="Cooley S">S Cooley</name></author><author><name sortKey="Xiao, F" uniqKey="Xiao F">F Xiao</name></author><author><name sortKey="Pitt, M" uniqKey="Pitt M">M Pitt</name></author><author><name sortKey="Gleason, M" uniqKey="Gleason M">M Gleason</name></author><author><name sortKey="Mccullar, V" uniqKey="Mccullar V">V McCullar</name></author><author><name sortKey="Bergemann, Tl" uniqKey="Bergemann T">TL Bergemann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huntington, Nd" uniqKey="Huntington N">ND Huntington</name></author><author><name sortKey="Legrand, N" uniqKey="Legrand N">N Legrand</name></author><author><name sortKey="Alves, Nl" uniqKey="Alves N">NL Alves</name></author><author><name sortKey="Jaron, B" uniqKey="Jaron B">B Jaron</name></author><author><name sortKey="Weijer, K" uniqKey="Weijer K">K Weijer</name></author><author><name sortKey="Plet, A" uniqKey="Plet A">A Plet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, C" uniqKey="Wu C">C Wu</name></author><author><name sortKey="Li, B" uniqKey="Li B">B Li</name></author><author><name sortKey="Lu, R" uniqKey="Lu R">R Lu</name></author><author><name sortKey="Koelle, Sj" uniqKey="Koelle S">SJ Koelle</name></author><author><name sortKey="Yang, Y" uniqKey="Yang Y">Y Yang</name></author><author><name sortKey="Jares, A" uniqKey="Jares A">A Jares</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Orange, Js" uniqKey="Orange J">JS Orange</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Biron, Ca" uniqKey="Biron C">CA Biron</name></author><author><name sortKey="Byron, Ks" uniqKey="Byron K">KS Byron</name></author><author><name sortKey="Sullivan, Jl" uniqKey="Sullivan J">JL Sullivan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mace, Em" uniqKey="Mace E">EM Mace</name></author><author><name sortKey="Hsu, Ap" uniqKey="Hsu A">AP Hsu</name></author><author><name sortKey="Monaco Shawver, L" uniqKey="Monaco Shawver L">L Monaco-Shawver</name></author><author><name sortKey="Makedonas, G" uniqKey="Makedonas G">G Makedonas</name></author><author><name sortKey="Rosen, Jb" uniqKey="Rosen J">JB Rosen</name></author><author><name sortKey="Dropulic, L" uniqKey="Dropulic L">L Dropulic</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dickinson, Re" uniqKey="Dickinson R">RE Dickinson</name></author><author><name sortKey="Griffin, H" uniqKey="Griffin H">H Griffin</name></author><author><name sortKey="Bigley, V" uniqKey="Bigley V">V Bigley</name></author><author><name sortKey="Reynard, Ln" uniqKey="Reynard L">LN Reynard</name></author><author><name sortKey="Hussain, R" uniqKey="Hussain R">R Hussain</name></author><author><name sortKey="Haniffa, M" uniqKey="Haniffa M">M Haniffa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hsu, Ap" uniqKey="Hsu A">AP Hsu</name></author><author><name sortKey="Sampaio, Ep" uniqKey="Sampaio E">EP Sampaio</name></author><author><name sortKey="Khan, J" uniqKey="Khan J">J Khan</name></author><author><name sortKey="Calvo, Kr" uniqKey="Calvo K">KR Calvo</name></author><author><name sortKey="Lemieux, Je" uniqKey="Lemieux J">JE Lemieux</name></author><author><name sortKey="Patel, Sy" uniqKey="Patel S">SY Patel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vinh, Dc" uniqKey="Vinh D">DC Vinh</name></author><author><name sortKey="Patel, Sy" uniqKey="Patel S">SY Patel</name></author><author><name sortKey="Uzel, G" uniqKey="Uzel G">G Uzel</name></author><author><name sortKey="Anderson, Vl" uniqKey="Anderson V">VL Anderson</name></author><author><name sortKey="Freeman, Af" uniqKey="Freeman A">AF Freeman</name></author><author><name sortKey="Olivier, Kn" uniqKey="Olivier K">KN Olivier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Maciejewski Duval, A" uniqKey="Maciejewski Duval A">A Maciejewski-Duval</name></author><author><name sortKey="Meuris, F" uniqKey="Meuris F">F Meuris</name></author><author><name sortKey="Bignon, A" uniqKey="Bignon A">A Bignon</name></author><author><name sortKey="Aknin, Ml" uniqKey="Aknin M">ML Aknin</name></author><author><name sortKey="Balabanian, K" uniqKey="Balabanian K">K Balabanian</name></author><author><name sortKey="Faivre, L" uniqKey="Faivre L">L Faivre</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dickinson, Re" uniqKey="Dickinson R">RE Dickinson</name></author><author><name sortKey="Milne, P" uniqKey="Milne P">P Milne</name></author><author><name sortKey="Jardine, L" uniqKey="Jardine L">L Jardine</name></author><author><name sortKey="Zandi, S" uniqKey="Zandi S">S Zandi</name></author><author><name sortKey="Swierczek, Si" uniqKey="Swierczek S">SI Swierczek</name></author><author><name sortKey="Mcgovern, N" uniqKey="Mcgovern N">N McGovern</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Spinner, Ma" uniqKey="Spinner M">MA Spinner</name></author><author><name sortKey="Sanchez, La" uniqKey="Sanchez L">LA Sanchez</name></author><author><name sortKey="Hsu, Ap" uniqKey="Hsu A">AP Hsu</name></author><author><name sortKey="Shaw, Pa" uniqKey="Shaw P">PA Shaw</name></author><author><name sortKey="Zerbe, Cs" uniqKey="Zerbe C">CS Zerbe</name></author><author><name sortKey="Calvo, Kr" uniqKey="Calvo K">KR Calvo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hahn, Cn" uniqKey="Hahn C">CN Hahn</name></author><author><name sortKey="Chong, Ce" uniqKey="Chong C">CE Chong</name></author><author><name sortKey="Carmichael, Cl" uniqKey="Carmichael C">CL Carmichael</name></author><author><name sortKey="Wilkins, Ej" uniqKey="Wilkins E">EJ Wilkins</name></author><author><name sortKey="Brautigan, Pj" uniqKey="Brautigan P">PJ Brautigan</name></author><author><name sortKey="Li, Xc" uniqKey="Li X">XC Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wlodarski, Mw" uniqKey="Wlodarski M">MW Wlodarski</name></author><author><name sortKey="Hirabayashi, S" uniqKey="Hirabayashi S">S Hirabayashi</name></author><author><name sortKey="Pastor, V" uniqKey="Pastor V">V Pastor</name></author><author><name sortKey="Star, J" uniqKey="Star J">J Starý</name></author><author><name sortKey="Hasle, H" uniqKey="Hasle H">H Hasle</name></author><author><name sortKey="Masetti, R" uniqKey="Masetti R">R Masetti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rodrigues, Np" uniqKey="Rodrigues N">NP Rodrigues</name></author><author><name sortKey="Janzen, V" uniqKey="Janzen V">V Janzen</name></author><author><name sortKey="Forkert, R" uniqKey="Forkert R">R Forkert</name></author><author><name sortKey="Dombkowski, Dm" uniqKey="Dombkowski D">DM Dombkowski</name></author><author><name sortKey="Boyd, As" uniqKey="Boyd A">AS Boyd</name></author><author><name sortKey="Orkin, Sh" uniqKey="Orkin S">SH Orkin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tipping, Aj" uniqKey="Tipping A">AJ Tipping</name></author><author><name sortKey="Pina, C" uniqKey="Pina C">C Pina</name></author><author><name sortKey="Castor, A" uniqKey="Castor A">A Castor</name></author><author><name sortKey="Hong, D" uniqKey="Hong D">D Hong</name></author><author><name sortKey="Rodrigues, Np" uniqKey="Rodrigues N">NP Rodrigues</name></author><author><name sortKey="Lazzari, L" uniqKey="Lazzari L">L Lazzari</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Su, Ai" uniqKey="Su A">AI Su</name></author><author><name sortKey="Wiltshire, T" uniqKey="Wiltshire T">T Wiltshire</name></author><author><name sortKey="Batalov, S" uniqKey="Batalov S">S Batalov</name></author><author><name sortKey="Lapp, H" uniqKey="Lapp H">H Lapp</name></author><author><name sortKey="Ching, Ka" uniqKey="Ching K">KA Ching</name></author><author><name sortKey="Block, D" uniqKey="Block D">D Block</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mabbott, Na" uniqKey="Mabbott N">NA Mabbott</name></author><author><name sortKey="Baillie, Jk" uniqKey="Baillie J">JK Baillie</name></author><author><name sortKey="Brown, H" uniqKey="Brown H">H Brown</name></author><author><name sortKey="Freeman, Tc" uniqKey="Freeman T">TC Freeman</name></author><author><name sortKey="Hume, Da" uniqKey="Hume D">DA Hume</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, C" uniqKey="Wu C">C Wu</name></author><author><name sortKey="Orozco, C" uniqKey="Orozco C">C Orozco</name></author><author><name sortKey="Boyer, J" uniqKey="Boyer J">J Boyer</name></author><author><name sortKey="Leglise, M" uniqKey="Leglise M">M Leglise</name></author><author><name sortKey="Goodale, J" uniqKey="Goodale J">J Goodale</name></author><author><name sortKey="Batalov, S" uniqKey="Batalov S">S Batalov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Onodera, K" uniqKey="Onodera K">K Onodera</name></author><author><name sortKey="Fujiwara, T" uniqKey="Fujiwara T">T Fujiwara</name></author><author><name sortKey="Onishi, Y" uniqKey="Onishi Y">Y Onishi</name></author><author><name sortKey="Itoh Nakadai, A" uniqKey="Itoh Nakadai A">A Itoh-Nakadai</name></author><author><name sortKey="Okitsu, Y" uniqKey="Okitsu Y">Y Okitsu</name></author><author><name sortKey="Fukuhara, N" uniqKey="Fukuhara N">N Fukuhara</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bresnick, Eh" uniqKey="Bresnick E">EH Bresnick</name></author><author><name sortKey="Lee, Hy" uniqKey="Lee H">HY Lee</name></author><author><name sortKey="Fujiwara, T" uniqKey="Fujiwara T">T Fujiwara</name></author><author><name sortKey="Johnson, Kd" uniqKey="Johnson K">KD Johnson</name></author><author><name sortKey="Keles, S" uniqKey="Keles S">S Keles</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bukowski, Jf" uniqKey="Bukowski J">JF Bukowski</name></author><author><name sortKey="Woda, Ba" uniqKey="Woda B">BA Woda</name></author><author><name sortKey="Welsh, Rm" uniqKey="Welsh R">RM Welsh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Welsh, Rm" uniqKey="Welsh R">RM Welsh</name></author><author><name sortKey="Brubaker, Jo" uniqKey="Brubaker J">JO Brubaker</name></author><author><name sortKey="Vargas Cortes, M" uniqKey="Vargas Cortes M">M Vargas-Cortes</name></author><author><name sortKey="O Onnell, Cl" uniqKey="O Onnell C">CL O’Donnell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Welsh, Rm" uniqKey="Welsh R">RM Welsh</name></author><author><name sortKey="O Onnell, Cl" uniqKey="O Onnell C">CL O’Donnell</name></author><author><name sortKey="Shultz, Ld" uniqKey="Shultz L">LD Shultz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eidenschenk, C" uniqKey="Eidenschenk C">C Eidenschenk</name></author><author><name sortKey="Dunne, J" uniqKey="Dunne J">J Dunne</name></author><author><name sortKey="Jouanguy, E" uniqKey="Jouanguy E">E Jouanguy</name></author><author><name sortKey="Fourlinnie, C" uniqKey="Fourlinnie C">C Fourlinnie</name></author><author><name sortKey="Gineau, L" uniqKey="Gineau L">L Gineau</name></author><author><name sortKey="Bacq, D" uniqKey="Bacq D">D Bacq</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gineau, L" uniqKey="Gineau L">L Gineau</name></author><author><name sortKey="Cognet, C" uniqKey="Cognet C">C Cognet</name></author><author><name sortKey="Kara, N" uniqKey="Kara N">N Kara</name></author><author><name sortKey="Lach, Fp" uniqKey="Lach F">FP Lach</name></author><author><name sortKey="Dunne, J" uniqKey="Dunne J">J Dunne</name></author><author><name sortKey="Veturi, U" uniqKey="Veturi U">U Veturi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hughes, Cr" uniqKey="Hughes C">CR Hughes</name></author><author><name sortKey="Guasti, L" uniqKey="Guasti L">L Guasti</name></author><author><name sortKey="Meimaridou, E" uniqKey="Meimaridou E">E Meimaridou</name></author><author><name sortKey="Chuang, Ch" uniqKey="Chuang C">CH Chuang</name></author><author><name sortKey="Schimenti, Jc" uniqKey="Schimenti J">JC Schimenti</name></author><author><name sortKey="King, Pj" uniqKey="King P">PJ King</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="O Iordan, Sm" uniqKey="O Iordan S">SM O’Riordan</name></author><author><name sortKey="Lynch, Sa" uniqKey="Lynch S">SA Lynch</name></author><author><name sortKey="Hindmarsh, Pc" uniqKey="Hindmarsh P">PC Hindmarsh</name></author><author><name sortKey="Chan, Lf" uniqKey="Chan L">LF Chan</name></author><author><name sortKey="Clark, Aj" uniqKey="Clark A">AJ Clark</name></author><author><name sortKey="Costigan, C" uniqKey="Costigan C">C Costigan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aparicio, T" uniqKey="Aparicio T">T Aparicio</name></author><author><name sortKey="Guillou, E" uniqKey="Guillou E">E Guillou</name></author><author><name sortKey="Coloma, J" uniqKey="Coloma J">J Coloma</name></author><author><name sortKey="Montoya, G" uniqKey="Montoya G">G Montoya</name></author><author><name sortKey="Mendez, J" uniqKey="Mendez J">J Méndez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Costa, A" uniqKey="Costa A">A Costa</name></author><author><name sortKey="Onesti, S" uniqKey="Onesti S">S Onesti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shima, N" uniqKey="Shima N">N Shima</name></author><author><name sortKey="Alcaraz, A" uniqKey="Alcaraz A">A Alcaraz</name></author><author><name sortKey="Liachko, I" uniqKey="Liachko I">I Liachko</name></author><author><name sortKey="Buske, Tr" uniqKey="Buske T">TR Buske</name></author><author><name sortKey="Andrews, Ca" uniqKey="Andrews C">CA Andrews</name></author><author><name sortKey="Munroe, Rj" uniqKey="Munroe R">RJ Munroe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lutz, Ct" uniqKey="Lutz C">CT Lutz</name></author><author><name sortKey="Karapetyan, A" uniqKey="Karapetyan A">A Karapetyan</name></author><author><name sortKey="Al Attar, A" uniqKey="Al Attar A">A Al-Attar</name></author><author><name sortKey="Shelton, Bj" uniqKey="Shelton B">BJ Shelton</name></author><author><name sortKey="Holt, Kj" uniqKey="Holt K">KJ Holt</name></author><author><name sortKey="Tucker, Jh" uniqKey="Tucker J">JH Tucker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Etzioni, A" uniqKey="Etzioni A">A Etzioni</name></author><author><name sortKey="Eidenschenk, C" uniqKey="Eidenschenk C">C Eidenschenk</name></author><author><name sortKey="Katz, R" uniqKey="Katz R">R Katz</name></author><author><name sortKey="Beck, R" uniqKey="Beck R">R Beck</name></author><author><name sortKey="Casanova, Jl" uniqKey="Casanova J">JL Casanova</name></author><author><name sortKey="Pollack, S" uniqKey="Pollack S">S Pollack</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hanna, S" uniqKey="Hanna S">S Hanna</name></author><author><name sortKey="Beziat, V" uniqKey="Beziat V">V Béziat</name></author><author><name sortKey="Jouanguy, E" uniqKey="Jouanguy E">E Jouanguy</name></author><author><name sortKey="Casanova, Jl" uniqKey="Casanova J">JL Casanova</name></author><author><name sortKey="Etzioni, A" uniqKey="Etzioni A">A Etzioni</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fedick, Am" uniqKey="Fedick A">AM Fedick</name></author><author><name sortKey="Shi, L" uniqKey="Shi L">L Shi</name></author><author><name sortKey="Jalas, C" uniqKey="Jalas C">C Jalas</name></author><author><name sortKey="Treff, Nr" uniqKey="Treff N">NR Treff</name></author><author><name sortKey="Ekstein, J" uniqKey="Ekstein J">J Ekstein</name></author><author><name sortKey="Kornreich, R" uniqKey="Kornreich R">R Kornreich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ballew, Bj" uniqKey="Ballew B">BJ Ballew</name></author><author><name sortKey="Joseph, V" uniqKey="Joseph V">V Joseph</name></author><author><name sortKey="De, S" uniqKey="De S">S De</name></author><author><name sortKey="Sarek, G" uniqKey="Sarek G">G Sarek</name></author><author><name sortKey="Vannier, Jb" uniqKey="Vannier J">JB Vannier</name></author><author><name sortKey="Stracker, T" uniqKey="Stracker T">T Stracker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ballew, Bj" uniqKey="Ballew B">BJ Ballew</name></author><author><name sortKey="Yeager, M" uniqKey="Yeager M">M Yeager</name></author><author><name sortKey="Jacobs, K" uniqKey="Jacobs K">K Jacobs</name></author><author><name sortKey="Giri, N" uniqKey="Giri N">N Giri</name></author><author><name sortKey="Boland, J" uniqKey="Boland J">J Boland</name></author><author><name sortKey="Burdett, L" uniqKey="Burdett L">L Burdett</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fleisher, G" uniqKey="Fleisher G">G Fleisher</name></author><author><name sortKey="Starr, S" uniqKey="Starr S">S Starr</name></author><author><name sortKey="Koven, N" uniqKey="Koven N">N Koven</name></author><author><name sortKey="Kamiya, H" uniqKey="Kamiya H">H Kamiya</name></author><author><name sortKey="Douglas, Sd" uniqKey="Douglas S">SD Douglas</name></author><author><name sortKey="Henle, W" uniqKey="Henle W">W Henle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mace, Em" uniqKey="Mace E">EM Mace</name></author><author><name sortKey="Bigley, V" uniqKey="Bigley V">V Bigley</name></author><author><name sortKey="Gunesch, Jt" uniqKey="Gunesch J">JT Gunesch</name></author><author><name sortKey="Chinn, Ik" uniqKey="Chinn I">IK Chinn</name></author><author><name sortKey="Cao, Tn" uniqKey="Cao T">TN Cao</name></author><author><name sortKey="Keller, Md" uniqKey="Keller M">MD Keller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Salem, S" uniqKey="Salem S">S Salem</name></author><author><name sortKey="Langlais, D" uniqKey="Langlais D">D Langlais</name></author><author><name sortKey="Lefebvre, F" uniqKey="Lefebvre F">F Lefebvre</name></author><author><name sortKey="Bourque, G" uniqKey="Bourque G">G Bourque</name></author><author><name sortKey="Bigley, V" uniqKey="Bigley V">V Bigley</name></author><author><name sortKey="Haniffa, M" uniqKey="Haniffa M">M Haniffa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hambleton, S" uniqKey="Hambleton S">S Hambleton</name></author><author><name sortKey="Salem, S" uniqKey="Salem S">S Salem</name></author><author><name sortKey="Bustamante, J" uniqKey="Bustamante J">J Bustamante</name></author><author><name sortKey="Bigley, V" uniqKey="Bigley V">V Bigley</name></author><author><name sortKey="Boisson Dupuis, S" uniqKey="Boisson Dupuis S">S Boisson-Dupuis</name></author><author><name sortKey="Azevedo, J" uniqKey="Azevedo J">J Azevedo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Vries, E" uniqKey="De Vries E">E de Vries</name></author><author><name sortKey="Koene, Hr" uniqKey="Koene H">HR Koene</name></author><author><name sortKey="Vossen, Jm" uniqKey="Vossen J">JM Vossen</name></author><author><name sortKey="Gratama, Jw" uniqKey="Gratama J">JW Gratama</name></author><author><name sortKey="Von Dem Borne, Ae" uniqKey="Von Dem Borne A">AE von dem Borne</name></author><author><name sortKey="Waaijer, Jl" uniqKey="Waaijer J">JL Waaijer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jawahar, S" uniqKey="Jawahar S">S Jawahar</name></author><author><name sortKey="Moody, C" uniqKey="Moody C">C Moody</name></author><author><name sortKey="Chan, M" uniqKey="Chan M">M Chan</name></author><author><name sortKey="Finberg, R" uniqKey="Finberg R">R Finberg</name></author><author><name sortKey="Geha, R" uniqKey="Geha R">R Geha</name></author><author><name sortKey="Chatila, T" uniqKey="Chatila T">T Chatila</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Grier, Jt" uniqKey="Grier J">JT Grier</name></author><author><name sortKey="Forbes, Lr" uniqKey="Forbes L">LR Forbes</name></author><author><name sortKey="Monaco Shawver, L" uniqKey="Monaco Shawver L">L Monaco-Shawver</name></author><author><name sortKey="Oshinsky, J" uniqKey="Oshinsky J">J Oshinsky</name></author><author><name sortKey="Atkinson, Tp" uniqKey="Atkinson T">TP Atkinson</name></author><author><name sortKey="Moody, C" uniqKey="Moody C">C Moody</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, Ll" uniqKey="Liu L">LL Liu</name></author><author><name sortKey="Landskron, J" uniqKey="Landskron J">J Landskron</name></author><author><name sortKey="Ask, Eh" uniqKey="Ask E">EH Ask</name></author><author><name sortKey="Enqvist, M" uniqKey="Enqvist M">M Enqvist</name></author><author><name sortKey="Sohlberg, E" uniqKey="Sohlberg E">E Sohlberg</name></author><author><name sortKey="Traherne, Ja" uniqKey="Traherne J">JA Traherne</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>États-Unis</li></country></list><tree><country name="États-Unis"><noRegion><name sortKey="Mace, Emily M" sort="Mace, Emily M" uniqKey="Mace E" first="Emily M." last="Mace">Emily M. 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