The Antitumor Effect of Gekko Sulfated Glycopeptide by Inhibiting bFGF-Induced Lymphangiogenesis
Identifieur interne : 000A60 ( Main/Exploration ); précédent : 000A59; suivant : 000A61The Antitumor Effect of Gekko Sulfated Glycopeptide by Inhibiting bFGF-Induced Lymphangiogenesis
Auteurs : Xiu-Li Ding [République populaire de Chine] ; Ya-Nan Man [République populaire de Chine] ; Jian Hao [République populaire de Chine] ; Cui-Hong Zhu [République populaire de Chine] ; Chang Liu [République populaire de Chine] ; Xue Yang [République populaire de Chine] ; Xiong-Zhi Wu [République populaire de Chine]Source :
- BioMed Research International [ 2314-6133 ] ; 2016.
Abstract
Url:
DOI: 10.1155/2016/7396392
PubMed: 27190997
PubMed Central: 4844873
Affiliations:
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type="city">Tianjin</settlement></placeName></affiliation></author><author><name sortKey="Wu, Xiong Zhi" sort="Wu, Xiong Zhi" uniqKey="Wu X" first="Xiong-Zhi" last="Wu">Xiong-Zhi Wu</name><affiliation wicri:level="1"><nlm:aff id="I1">Zhong-Shan-Men In-Patient Department, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Huan-Hu-Xi Road, He-Xi District, Tianjin 300060, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Zhong-Shan-Men In-Patient Department, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Huan-Hu-Xi Road, He-Xi District, Tianjin 300060</wicri:regionArea><placeName><settlement type="city">Tianjin</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno 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type="wicri:Area/Main/Exploration">000A60</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Antitumor Effect of Gekko Sulfated Glycopeptide by Inhibiting bFGF-Induced Lymphangiogenesis</title><author><name sortKey="Ding, Xiu Li" sort="Ding, Xiu Li" uniqKey="Ding X" first="Xiu-Li" last="Ding">Xiu-Li Ding</name><affiliation wicri:level="1"><nlm:aff id="I1">Zhong-Shan-Men In-Patient Department, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Huan-Hu-Xi Road, He-Xi District, Tianjin 300060, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Zhong-Shan-Men In-Patient Department, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Huan-Hu-Xi Road, He-Xi District, Tianjin 300060</wicri:regionArea><placeName><settlement type="city">Tianjin</settlement></placeName></affiliation></author><author><name sortKey="Man, Ya Nan" sort="Man, Ya Nan" uniqKey="Man Y" first="Ya-Nan" last="Man">Ya-Nan Man</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Radiotherapy, The Second Affiliated Hospital of Tianjin Medical University, Ping-Jiang Road, He-Xi District, Tianjin 300060, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Radiotherapy, The Second Affiliated Hospital of Tianjin Medical University, Ping-Jiang Road, He-Xi District, Tianjin 300060</wicri:regionArea><placeName><settlement type="city">Tianjin</settlement></placeName></affiliation></author><author><name sortKey="Hao, Jian" sort="Hao, Jian" uniqKey="Hao J" first="Jian" last="Hao">Jian Hao</name><affiliation wicri:level="1"><nlm:aff id="I1">Zhong-Shan-Men In-Patient Department, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Huan-Hu-Xi Road, He-Xi District, Tianjin 300060, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Zhong-Shan-Men In-Patient Department, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Huan-Hu-Xi Road, He-Xi District, Tianjin 300060</wicri:regionArea><placeName><settlement type="city">Tianjin</settlement></placeName></affiliation></author><author><name sortKey="Zhu, Cui Hong" sort="Zhu, Cui Hong" uniqKey="Zhu C" first="Cui-Hong" last="Zhu">Cui-Hong Zhu</name><affiliation wicri:level="1"><nlm:aff id="I1">Zhong-Shan-Men In-Patient Department, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Huan-Hu-Xi Road, He-Xi District, Tianjin 300060, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Zhong-Shan-Men In-Patient Department, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Huan-Hu-Xi Road, He-Xi District, Tianjin 300060</wicri:regionArea><placeName><settlement type="city">Tianjin</settlement></placeName></affiliation></author><author><name sortKey="Liu, Chang" sort="Liu, Chang" uniqKey="Liu C" first="Chang" last="Liu">Chang Liu</name><affiliation wicri:level="1"><nlm:aff id="I1">Zhong-Shan-Men In-Patient Department, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Huan-Hu-Xi Road, He-Xi District, Tianjin 300060, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Zhong-Shan-Men In-Patient Department, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Huan-Hu-Xi Road, He-Xi District, Tianjin 300060</wicri:regionArea><placeName><settlement type="city">Tianjin</settlement></placeName></affiliation></author><author><name sortKey="Yang, Xue" sort="Yang, Xue" uniqKey="Yang X" first="Xue" last="Yang">Xue Yang</name><affiliation wicri:level="1"><nlm:aff id="I1">Zhong-Shan-Men In-Patient Department, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Huan-Hu-Xi Road, He-Xi District, Tianjin 300060, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Zhong-Shan-Men In-Patient Department, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Huan-Hu-Xi Road, He-Xi District, Tianjin 300060</wicri:regionArea><placeName><settlement type="city">Tianjin</settlement></placeName></affiliation></author><author><name sortKey="Wu, Xiong Zhi" sort="Wu, Xiong Zhi" uniqKey="Wu X" first="Xiong-Zhi" last="Wu">Xiong-Zhi Wu</name><affiliation wicri:level="1"><nlm:aff id="I1">Zhong-Shan-Men In-Patient Department, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Huan-Hu-Xi Road, He-Xi District, Tianjin 300060, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Zhong-Shan-Men In-Patient Department, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Huan-Hu-Xi Road, He-Xi District, Tianjin 300060</wicri:regionArea><placeName><settlement type="city">Tianjin</settlement></placeName></affiliation></author></analytic><series><title level="j">BioMed Research International</title><idno type="ISSN">2314-6133</idno><idno type="eISSN">2314-6141</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><italic>Objective</italic>. To study the antilymphangiogenesis effect of Gekko Sulfated Glycopeptide (GSPP) on human lymphatic endothelial cells (hLECs).<italic> Methods</italic>. MTS was conducted to confirm the antiproliferation effect of GSPP on hLECs; flow cytometry was employed to detect hLECs cycle distribution; the antimigration effect of GSPP on hLECs was investigated by wound healing experiment and transwell experiment; tube formation assay was used to examine its inhibitory effect on the lymphangiogenesis; western blotting was conducted to detect the expression of extracellular signal-regulated kinase1/2 (Erk1/2) and p-Erk1/2 after GSPP and basic fibroblast growth factor (bFGF) treatment. Nude mice models were established to investigate the antitumor effect of GSPP in vivo. Decreased lymphangiogenesis caused by GSPP in vivo was verified by immunohistochemical staining.<italic> Results</italic>. In vitro, GSPP (10 <italic>μ</italic>g/mL, 100 <italic>μ</italic>g/mL) significantly inhibited bFGF-induced hLECs proliferation, migration, and tube-like structure formation (<italic>P</italic> < 0.05) and antagonized the phosphorylation activation of Erk1/2 induced by bFGF. In vivo, GSPP treatment (200 mg/kg/d) not only inhibited the growth of colon carcinoma, but also inhibited the tumor lymphangiogenesis.<italic> Conclusion</italic>. GSPP possesses the antitumor ability by inhibiting bFGF-inducing lymphangiogenesis in vitro and in vivo, which may further inhibit tumor lymphatic metastasis.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Robert, J" uniqKey="Robert J">J. Robert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bicknell, R" uniqKey="Bicknell R">R. Bicknell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ribatti, D" uniqKey="Ribatti D">D. Ribatti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shayan, R" uniqKey="Shayan R">R. Shayan</name></author><author><name sortKey="Achen, M G" uniqKey="Achen M">M. G. Achen</name></author><author><name sortKey="Stacker, S A" uniqKey="Stacker S">S. A. Stacker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sleeman, J P" uniqKey="Sleeman J">J. P. Sleeman</name></author><author><name sortKey="Thiele, W" uniqKey="Thiele W">W. Thiele</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ferris, R L" uniqKey="Ferris R">R. L. Ferris</name></author><author><name sortKey="Lotze, M T" uniqKey="Lotze M">M. T. Lotze</name></author><author><name sortKey="Leong, S P L" uniqKey="Leong S">S. P. L. Leong</name></author><author><name sortKey="Hoon, D S B" uniqKey="Hoon D">D. S. B. Hoon</name></author><author><name sortKey="Morton, D L" uniqKey="Morton D">D. L. Morton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sundar, S S" uniqKey="Sundar S">S. S. Sundar</name></author><author><name sortKey="Ganesan, T S" uniqKey="Ganesan T">T. S. Ganesan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Achen, M G" uniqKey="Achen M">M. G. Achen</name></author><author><name sortKey="Mccoll, B K" uniqKey="Mccoll B">B. K. McColl</name></author><author><name sortKey="Stacker, S A" uniqKey="Stacker S">S. A. Stacker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Adams, R H" uniqKey="Adams R">R. H. Adams</name></author><author><name sortKey="Alitalo, K" uniqKey="Alitalo K">K. Alitalo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Linares, P M" uniqKey="Linares P">P. M. Linares</name></author><author><name sortKey="Gisbert, J P" uniqKey="Gisbert J">J. P. Gisbert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chang, L K" uniqKey="Chang L">L. K. Chang</name></author><author><name sortKey="Garcia Carde A, G" uniqKey="Garcia Carde A G">G. Garcia-Cardeña</name></author><author><name sortKey="Farnebo, F" uniqKey="Farnebo F">F. Farnebo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, S X" uniqKey="Zhang S">S.-X. Zhang</name></author><author><name sortKey="Zhu, C" uniqKey="Zhu C">C. Zhu</name></author><author><name sortKey="Ba, Y" uniqKey="Ba Y">Y. Ba</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Benezra, M" uniqKey="Benezra M">M. Benezra</name></author><author><name sortKey="Ishai Michaeli, R" uniqKey="Ishai Michaeli R">R. Ishai-Michaeli</name></author><author><name sortKey="Ben Sasson, S A" uniqKey="Ben Sasson S">S. A. Ben-Sasson</name></author><author><name sortKey="Vlodavsky, I" uniqKey="Vlodavsky I">I. Vlodavsky</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fannon, M" uniqKey="Fannon M">M. Fannon</name></author><author><name sortKey="Forsten, K E" uniqKey="Forsten K">K. E. Forsten</name></author><author><name sortKey="Nugent, M A" uniqKey="Nugent M">M. A. Nugent</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, D" uniqKey="Chen D">D. Chen</name></author><author><name sortKey="Yao, W J" uniqKey="Yao W">W.-J. Yao</name></author><author><name sortKey="Zhang, X L" uniqKey="Zhang X">X.-L. Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, X" uniqKey="Wu X">X. Wu</name></author><author><name sortKey="Chen, D" uniqKey="Chen D">D. Chen</name></author><author><name sortKey="Xie, G R" uniqKey="Xie G">G.-R. Xie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, X Z" uniqKey="Wu X">X.-Z. Wu</name></author><author><name sortKey="Chen, D" uniqKey="Chen D">D. Chen</name></author><author><name sortKey="Han, X Q" uniqKey="Han X">X.-Q. Han</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, L" uniqKey="Yang L">L. Yang</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J. Zhang</name></author><author><name sortKey="Wang, C" uniqKey="Wang C">C. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Balmanno, K" uniqKey="Balmanno K">K. Balmanno</name></author><author><name sortKey="Cook, S J" uniqKey="Cook S">S. J. Cook</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tobler, N E" uniqKey="Tobler N">N. E. Tobler</name></author><author><name sortKey="Detmar, M" uniqKey="Detmar M">M. Detmar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cao, Y" uniqKey="Cao Y">Y. Cao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alitalo, K" uniqKey="Alitalo K">K. Alitalo</name></author><author><name sortKey="Tammela, T" uniqKey="Tammela T">T. Tammela</name></author><author><name sortKey="Petrova, T V" uniqKey="Petrova T">T. V. Petrova</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Skobe, M" uniqKey="Skobe M">M. Skobe</name></author><author><name sortKey="Hawighorst, T" uniqKey="Hawighorst T">T. Hawighorst</name></author><author><name sortKey="Jackson, D G" uniqKey="Jackson D">D. G. Jackson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stacker, S A" uniqKey="Stacker S">S. A. Stacker</name></author><author><name sortKey="Caesar, C" uniqKey="Caesar C">C. Caesar</name></author><author><name sortKey="Baldwin, M E" uniqKey="Baldwin M">M. E. Baldwin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pepper, M S" uniqKey="Pepper M">M. S. Pepper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, C L" uniqKey="Yang C">C. L. Yang</name></author><author><name sortKey="Qi, Y J" uniqKey="Qi Y">Y. J. Qi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cao, R" uniqKey="Cao R">R. Cao</name></author><author><name sortKey="Eriksson, A" uniqKey="Eriksson A">A. Eriksson</name></author><author><name sortKey="Kubo, H" uniqKey="Kubo H">H. Kubo</name></author><author><name sortKey="Alitalo, K" uniqKey="Alitalo K">K. Alitalo</name></author><author><name sortKey="Cao, Y" uniqKey="Cao Y">Y. Cao</name></author><author><name sortKey="Thyberg, J" uniqKey="Thyberg J">J. Thyberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Karkkainen, M J" uniqKey="Karkkainen M">M. J. Karkkainen</name></author><author><name sortKey="Ferrell, R E" uniqKey="Ferrell R">R. E. Ferrell</name></author><author><name sortKey="Lawrence, E C" uniqKey="Lawrence E">E. C. Lawrence</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guo, S" uniqKey="Guo S">S. Guo</name></author><author><name sortKey="Yu, L" uniqKey="Yu L">L. Yu</name></author><author><name sortKey="Cheng, Y" uniqKey="Cheng Y">Y. Cheng</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li></country><settlement><li>Tianjin</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Ding, Xiu Li" sort="Ding, Xiu Li" uniqKey="Ding X" first="Xiu-Li" last="Ding">Xiu-Li Ding</name></noRegion><name sortKey="Hao, Jian" sort="Hao, Jian" uniqKey="Hao J" first="Jian" last="Hao">Jian Hao</name><name sortKey="Liu, Chang" sort="Liu, Chang" uniqKey="Liu C" first="Chang" last="Liu">Chang Liu</name><name sortKey="Man, Ya Nan" sort="Man, Ya Nan" uniqKey="Man Y" first="Ya-Nan" last="Man">Ya-Nan Man</name><name sortKey="Wu, Xiong Zhi" sort="Wu, Xiong Zhi" uniqKey="Wu X" first="Xiong-Zhi" last="Wu">Xiong-Zhi Wu</name><name sortKey="Yang, Xue" sort="Yang, Xue" uniqKey="Yang X" first="Xue" last="Yang">Xue Yang</name><name sortKey="Zhu, Cui Hong" sort="Zhu, Cui Hong" uniqKey="Zhu C" first="Cui-Hong" last="Zhu">Cui-Hong Zhu</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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