Handheld Reflectance Confocal Microscopy to Aid in the Management of Complex Facial Lentigo Maligna
Identifieur interne : 000523 ( Main/Exploration ); précédent : 000522; suivant : 000524Handheld Reflectance Confocal Microscopy to Aid in the Management of Complex Facial Lentigo Maligna
Auteurs : Brian P. Hibler ; Oriol Yélamos ; Miguel Cordova ; Heidy Sierra ; Milind Rajadhyaksha ; Kishwer S. Nehal ; Anthony M. RossiSource :
- Cutis [ 0011-4162 ] ; 2017.
Abstract
Diagnosis and management of lentigo maligna (LM) and LM melanoma (LMM) is challenging. Novel noninvasive imaging technologies such as reflectance confocal microscopy (RCM) have advanced the ability to better diagnose and monitor challenging lesions. In addition, the new handheld RCM (HRCM) together with the use of videomosaics has allowed an accurate evaluation of large lesions in concave/convex areas of the body (eg, the face). Herein, we review the impact of HRCM in the detection, treatment decision-making, and monitoring of 5 cases of complex facial LM/LMM. In the cases presented, HRCM enabled the detection of subclinical margins, presence of invasion, detection of persistence/recurrence, and monitoring of surgical and nonsurgical therapies. In this preliminary report, our results suggest that HRCM is a versatile ancillary tool in pretreatment decision-making, intraoperative surgical mapping, and posttreatment monitoring of complex facial LM/LMM.
Url:
PubMed: 28632796
PubMed Central: 5569302
Affiliations:
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Hibler</name></author><author><name sortKey="Yelamos, Oriol" sort="Yelamos, Oriol" uniqKey="Yelamos O" first="Oriol" last="Yélamos">Oriol Yélamos</name></author><author><name sortKey="Cordova, Miguel" sort="Cordova, Miguel" uniqKey="Cordova M" first="Miguel" last="Cordova">Miguel Cordova</name></author><author><name sortKey="Sierra, Heidy" sort="Sierra, Heidy" uniqKey="Sierra H" first="Heidy" last="Sierra">Heidy Sierra</name></author><author><name sortKey="Rajadhyaksha, Milind" sort="Rajadhyaksha, Milind" uniqKey="Rajadhyaksha M" first="Milind" last="Rajadhyaksha">Milind Rajadhyaksha</name></author><author><name sortKey="Nehal, Kishwer S" sort="Nehal, Kishwer S" uniqKey="Nehal K" first="Kishwer S." last="Nehal">Kishwer S. Nehal</name></author><author><name sortKey="Rossi, Anthony M" sort="Rossi, Anthony M" uniqKey="Rossi A" first="Anthony M." last="Rossi">Anthony M. 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Hibler</name></author><author><name sortKey="Yelamos, Oriol" sort="Yelamos, Oriol" uniqKey="Yelamos O" first="Oriol" last="Yélamos">Oriol Yélamos</name></author><author><name sortKey="Cordova, Miguel" sort="Cordova, Miguel" uniqKey="Cordova M" first="Miguel" last="Cordova">Miguel Cordova</name></author><author><name sortKey="Sierra, Heidy" sort="Sierra, Heidy" uniqKey="Sierra H" first="Heidy" last="Sierra">Heidy Sierra</name></author><author><name sortKey="Rajadhyaksha, Milind" sort="Rajadhyaksha, Milind" uniqKey="Rajadhyaksha M" first="Milind" last="Rajadhyaksha">Milind Rajadhyaksha</name></author><author><name sortKey="Nehal, Kishwer S" sort="Nehal, Kishwer S" uniqKey="Nehal K" first="Kishwer S." last="Nehal">Kishwer S. Nehal</name></author><author><name sortKey="Rossi, Anthony M" sort="Rossi, Anthony M" uniqKey="Rossi A" first="Anthony M." last="Rossi">Anthony M. Rossi</name></author></analytic><series><title level="j">Cutis</title><idno type="ISSN">0011-4162</idno><idno type="eISSN">2326-6929</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Diagnosis and management of lentigo maligna (LM) and LM melanoma (LMM) is challenging. Novel noninvasive imaging technologies such as reflectance confocal microscopy (RCM) have advanced the ability to better diagnose and monitor challenging lesions. In addition, the new handheld RCM (HRCM) together with the use of videomosaics has allowed an accurate evaluation of large lesions in concave/convex areas of the body (eg, the face). Herein, we review the impact of HRCM in the detection, treatment decision-making, and monitoring of 5 cases of complex facial LM/LMM. In the cases presented, HRCM enabled the detection of subclinical margins, presence of invasion, detection of persistence/recurrence, and monitoring of surgical and nonsurgical therapies. In this preliminary report, our results suggest that HRCM is a versatile ancillary tool in pretreatment decision-making, intraoperative surgical mapping, and posttreatment monitoring of complex facial LM/LMM.</p></div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Cordova, Miguel" sort="Cordova, Miguel" uniqKey="Cordova M" first="Miguel" last="Cordova">Miguel Cordova</name><name sortKey="Hibler, Brian P" sort="Hibler, Brian P" uniqKey="Hibler B" first="Brian P." last="Hibler">Brian P. Hibler</name><name sortKey="Nehal, Kishwer S" sort="Nehal, Kishwer S" uniqKey="Nehal K" first="Kishwer S." last="Nehal">Kishwer S. Nehal</name><name sortKey="Rajadhyaksha, Milind" sort="Rajadhyaksha, Milind" uniqKey="Rajadhyaksha M" first="Milind" last="Rajadhyaksha">Milind Rajadhyaksha</name><name sortKey="Rossi, Anthony M" sort="Rossi, Anthony M" uniqKey="Rossi A" first="Anthony M." last="Rossi">Anthony M. Rossi</name><name sortKey="Sierra, Heidy" sort="Sierra, Heidy" uniqKey="Sierra H" first="Heidy" last="Sierra">Heidy Sierra</name><name sortKey="Yelamos, Oriol" sort="Yelamos, Oriol" uniqKey="Yelamos O" first="Oriol" last="Yélamos">Oriol Yélamos</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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