Impact of Platelet-Rich Plasma on Viability and Proliferation in Wound Healing Processes after External Radiation
Identifieur interne : 000495 ( Main/Exploration ); précédent : 000494; suivant : 000496Impact of Platelet-Rich Plasma on Viability and Proliferation in Wound Healing Processes after External Radiation
Auteurs : Yvonne Reinders [Allemagne] ; Oliver Felthaus ; Gero Brockhoff ; Fabian Pohl ; Norbert Ahrens ; Lukas Prantl ; Frank Haubner [Allemagne]Source :
- International Journal of Molecular Sciences [ 1422-0067 ] ; 2017.
Abstract
Platelet-rich plasma is a current subject of studies on chronic wound healing therapy due to possible pro-angiogenic effects. Microvascular compromise represents the major component in radiogenic wound healing complications. The effects of platelet-rich plasma on irradiated cells of the cutaneous wound healing process are poorly understood so far. In this study, the interaction of endothelial cells and adipose-derived stem cells in conjunction with treatment with platelet-rich plasma is investigated in the context of radiation effects. Therefore, the expression of surface-marker CD90 and CD31 was determined. Moreover, cell proliferation and viability after external radiation was analyzed with and without treatment by platelet-rich plasma.
Url:
DOI: 10.3390/ijms18081819
PubMed: 28829358
PubMed Central: 5578205
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>Platelet-rich plasma is a current subject of studies on chronic wound healing therapy due to possible pro-angiogenic effects. Microvascular compromise represents the major component in radiogenic wound healing complications. The effects of platelet-rich plasma on irradiated cells of the cutaneous wound healing process are poorly understood so far. In this study, the interaction of endothelial cells and adipose-derived stem cells in conjunction with treatment with platelet-rich plasma is investigated in the context of radiation effects. Therefore, the expression of surface-marker CD90 and CD31 was determined. Moreover, cell proliferation and viability after external radiation was analyzed with and without treatment by platelet-rich plasma.</p>
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</TEI>
<affiliations><list><country><li>Allemagne</li>
</country>
<region><li>Basse-Saxe</li>
<li>Bavière</li>
<li>District de Haute-Bavière</li>
</region>
<settlement><li>Göttingen</li>
<li>Munich</li>
</settlement>
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<name sortKey="Felthaus, Oliver" sort="Felthaus, Oliver" uniqKey="Felthaus O" first="Oliver" last="Felthaus">Oliver Felthaus</name>
<name sortKey="Pohl, Fabian" sort="Pohl, Fabian" uniqKey="Pohl F" first="Fabian" last="Pohl">Fabian Pohl</name>
<name sortKey="Prantl, Lukas" sort="Prantl, Lukas" uniqKey="Prantl L" first="Lukas" last="Prantl">Lukas Prantl</name>
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<name sortKey="Haubner, Frank" sort="Haubner, Frank" uniqKey="Haubner F" first="Frank" last="Haubner">Frank Haubner</name>
<name sortKey="Haubner, Frank" sort="Haubner, Frank" uniqKey="Haubner F" first="Frank" last="Haubner">Frank Haubner</name>
<name sortKey="Haubner, Frank" sort="Haubner, Frank" uniqKey="Haubner F" first="Frank" last="Haubner">Frank Haubner</name>
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</record>
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