Novel bright-emission small-molecule NIR-II fluorophores for in vivo tumor imaging and image-guided surgery††Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc00251cClick here for additional data file.
Identifieur interne : 000336 ( Main/Exploration ); précédent : 000335; suivant : 000337Novel bright-emission small-molecule NIR-II fluorophores for in vivo tumor imaging and image-guided surgery††Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc00251cClick here for additional data file.
Auteurs : Yao Sun [République populaire de Chine] ; Mingmin Ding ; Xiaodong Zeng ; Yuling Xiao ; Huaping Wu ; Hui Zhou ; Bingbing Ding ; Chunrong Qu ; Wei Hou ; Aga Er-Bu [République populaire de Chine] ; Yejun Zhang [République populaire de Chine] ; Zhen Cheng [États-Unis] ; Xuechuan Hong [République populaire de Chine]Source :
- Chemical Science [ 2041-6520 ] ; 2017.
Abstract
This work presents the establishment of novel bright-emission small-molecule NIR-II fluorophores for
Url:
DOI: 10.1039/c7sc00251c
PubMed: 28507722
PubMed Central: 5418643
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Novel bright-emission small-molecule NIR-II fluorophores for <italic>in vivo</italic> tumor imaging and image-guided surgery<xref ref-type="fn" rid="fn1">†</xref><fn id="fn1"><p>†Electronic supplementary information (ESI) available. See DOI: <uri xlink:type="simple" xlink:href="http://dx.doi.org/10.1039/c7sc00251c">10.1039/c7sc00251c</uri><supplementary-material content-type="local-data" id="S1"><media xlink:href="SC-008-C7SC00251C-s001.pdf"><caption><p>Click here for additional data file.</p></caption></media></supplementary-material></p></fn></title><author><name sortKey="Sun, Yao" sort="Sun, Yao" uniqKey="Sun Y" first="Yao" last="Sun">Yao Sun</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="affb"> Key Laboratory of Pesticides and Chemical Biology , Ministry of Education , College of Chemistry , Central China Normal University , Wuhan 430079 , China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Key Laboratory of Pesticides and Chemical Biology , Ministry of Education , College of Chemistry , Central China Normal University , Wuhan 430079 </wicri:regionArea><wicri:noRegion>Wuhan 430079 </wicri:noRegion></affiliation></author><author><name sortKey="Ding, Mingmin" sort="Ding, Mingmin" uniqKey="Ding M" first="Mingmin" last="Ding">Mingmin Ding</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Zeng, Xiaodong" sort="Zeng, Xiaodong" uniqKey="Zeng X" first="Xiaodong" last="Zeng">Xiaodong Zeng</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Xiao, Yuling" sort="Xiao, Yuling" uniqKey="Xiao Y" first="Yuling" last="Xiao">Yuling Xiao</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Wu, Huaping" sort="Wu, Huaping" uniqKey="Wu H" first="Huaping" last="Wu">Huaping Wu</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Zhou, Hui" sort="Zhou, Hui" uniqKey="Zhou H" first="Hui" last="Zhou">Hui Zhou</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Ding, Bingbing" sort="Ding, Bingbing" uniqKey="Ding B" first="Bingbing" last="Ding">Bingbing Ding</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Qu, Chunrong" sort="Qu, Chunrong" uniqKey="Qu C" first="Chunrong" last="Qu">Chunrong Qu</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Hou, Wei" sort="Hou, Wei" uniqKey="Hou W" first="Wei" last="Hou">Wei Hou</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Er Bu, Aga" sort="Er Bu, Aga" uniqKey="Er Bu A" first="Aga" last="Er-Bu">Aga Er-Bu</name><affiliation wicri:level="1"><nlm:aff id="affd"> Medical College , Tibet University , Lasa , 850000 , China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Medical College , Tibet University , Lasa , 850000 </wicri:regionArea><wicri:noRegion>850000 </wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Yejun" sort="Zhang, Yejun" uniqKey="Zhang Y" first="Yejun" last="Zhang">Yejun Zhang</name><affiliation wicri:level="1"><nlm:aff id="affe"> Suzhou NIR-Optics Technologies Co., Ltd , Suzhou , 215123 , China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Suzhou NIR-Optics Technologies Co., Ltd , Suzhou , 215123 </wicri:regionArea><wicri:noRegion>215123 </wicri:noRegion></affiliation></author><author><name sortKey="Cheng, Zhen" sort="Cheng, Zhen" uniqKey="Cheng Z" first="Zhen" last="Cheng">Zhen Cheng</name><affiliation wicri:level="1"><nlm:aff id="affc"> Molecular Imaging Program at Stanford (MIPS) , Bio-X Program , Department of Radiology , Stanford University , California 94305-5344 , USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Molecular Imaging Program at Stanford (MIPS) , Bio-X Program , Department of Radiology , Stanford University , California 94305-5344 </wicri:regionArea><wicri:noRegion>California 94305-5344 </wicri:noRegion></affiliation></author><author><name sortKey="Hong, Xuechuan" sort="Hong, Xuechuan" uniqKey="Hong X" first="Xuechuan" last="Hong">Xuechuan Hong</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="affd"> Medical College , Tibet University , Lasa , 850000 , China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Medical College , Tibet University , Lasa , 850000 </wicri:regionArea><wicri:noRegion>850000 </wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">28507722</idno><idno type="pmc">5418643</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418643</idno><idno type="RBID">PMC:5418643</idno><idno type="doi">10.1039/c7sc00251c</idno><date when="2017">2017</date><idno type="wicri:Area/Pmc/Corpus">003D42</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003D42</idno><idno type="wicri:Area/Pmc/Curation">003D41</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003D41</idno><idno type="wicri:Area/Pmc/Checkpoint">000163</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000163</idno><idno type="wicri:Area/Ncbi/Merge">009082</idno><idno type="wicri:Area/Ncbi/Curation">009082</idno><idno type="wicri:Area/Ncbi/Checkpoint">009082</idno><idno type="wicri:doubleKey">2041-6520:2017:Sun Y:novel:bright:emission</idno><idno type="wicri:Area/Main/Merge">000336</idno><idno type="wicri:Area/Main/Curation">000336</idno><idno type="wicri:Area/Main/Exploration">000336</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Novel bright-emission small-molecule NIR-II fluorophores for <italic>in vivo</italic> tumor imaging and image-guided surgery<xref ref-type="fn" rid="fn1">†</xref><fn id="fn1"><p>†Electronic supplementary information (ESI) available. See DOI: <uri xlink:type="simple" xlink:href="http://dx.doi.org/10.1039/c7sc00251c">10.1039/c7sc00251c</uri><supplementary-material content-type="local-data" id="S1"><media xlink:href="SC-008-C7SC00251C-s001.pdf"><caption><p>Click here for additional data file.</p></caption></media></supplementary-material></p></fn></title><author><name sortKey="Sun, Yao" sort="Sun, Yao" uniqKey="Sun Y" first="Yao" last="Sun">Yao Sun</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="affb"> Key Laboratory of Pesticides and Chemical Biology , Ministry of Education , College of Chemistry , Central China Normal University , Wuhan 430079 , China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Key Laboratory of Pesticides and Chemical Biology , Ministry of Education , College of Chemistry , Central China Normal University , Wuhan 430079 </wicri:regionArea><wicri:noRegion>Wuhan 430079 </wicri:noRegion></affiliation></author><author><name sortKey="Ding, Mingmin" sort="Ding, Mingmin" uniqKey="Ding M" first="Mingmin" last="Ding">Mingmin Ding</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Zeng, Xiaodong" sort="Zeng, Xiaodong" uniqKey="Zeng X" first="Xiaodong" last="Zeng">Xiaodong Zeng</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Xiao, Yuling" sort="Xiao, Yuling" uniqKey="Xiao Y" first="Yuling" last="Xiao">Yuling Xiao</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Wu, Huaping" sort="Wu, Huaping" uniqKey="Wu H" first="Huaping" last="Wu">Huaping Wu</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Zhou, Hui" sort="Zhou, Hui" uniqKey="Zhou H" first="Hui" last="Zhou">Hui Zhou</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Ding, Bingbing" sort="Ding, Bingbing" uniqKey="Ding B" first="Bingbing" last="Ding">Bingbing Ding</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Qu, Chunrong" sort="Qu, Chunrong" uniqKey="Qu C" first="Chunrong" last="Qu">Chunrong Qu</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Hou, Wei" sort="Hou, Wei" uniqKey="Hou W" first="Wei" last="Hou">Wei Hou</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation></author><author><name sortKey="Er Bu, Aga" sort="Er Bu, Aga" uniqKey="Er Bu A" first="Aga" last="Er-Bu">Aga Er-Bu</name><affiliation wicri:level="1"><nlm:aff id="affd"> Medical College , Tibet University , Lasa , 850000 , China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Medical College , Tibet University , Lasa , 850000 </wicri:regionArea><wicri:noRegion>850000 </wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Yejun" sort="Zhang, Yejun" uniqKey="Zhang Y" first="Yejun" last="Zhang">Yejun Zhang</name><affiliation wicri:level="1"><nlm:aff id="affe"> Suzhou NIR-Optics Technologies Co., Ltd , Suzhou , 215123 , China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Suzhou NIR-Optics Technologies Co., Ltd , Suzhou , 215123 </wicri:regionArea><wicri:noRegion>215123 </wicri:noRegion></affiliation></author><author><name sortKey="Cheng, Zhen" sort="Cheng, Zhen" uniqKey="Cheng Z" first="Zhen" last="Cheng">Zhen Cheng</name><affiliation wicri:level="1"><nlm:aff id="affc"> Molecular Imaging Program at Stanford (MIPS) , Bio-X Program , Department of Radiology , Stanford University , California 94305-5344 , USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Molecular Imaging Program at Stanford (MIPS) , Bio-X Program , Department of Radiology , Stanford University , California 94305-5344 </wicri:regionArea><wicri:noRegion>California 94305-5344 </wicri:noRegion></affiliation></author><author><name sortKey="Hong, Xuechuan" sort="Hong, Xuechuan" uniqKey="Hong X" first="Xuechuan" last="Hong">Xuechuan Hong</name><affiliation><nlm:aff id="affa"> State Key Laboratory of Virology , Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) , Hubei Provincial Key Laboratory of Developmentally Originated Disease , Wuhan University School of Pharmaceutical Sciences , Wuhan 430071 , China . Email:<email>xhy78@whu.edu.cn</email></nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="affd"> Medical College , Tibet University , Lasa , 850000 , China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Medical College , Tibet University , Lasa , 850000 </wicri:regionArea><wicri:noRegion>850000 </wicri:noRegion></affiliation></author></analytic><series><title level="j">Chemical Science</title><idno type="ISSN">2041-6520</idno><idno type="eISSN">2041-6539</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><graphic xlink:href="c7sc00251c-ga.jpg" id="ga" position="float" orientation="portrait"></graphic>This work presents the establishment of novel bright-emission small-molecule NIR-II fluorophores for <italic>in vivo</italic> tumor imaging and NIR-II image-guided sentinel lymph node surgery.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Hong, G S" uniqKey="Hong G">G. 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