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Management of subclavian-axillary vein thrombosis: a review

Identifieur interne : 00B094 ( Main/Curation ); précédent : 00B093; suivant : 00B095

Management of subclavian-axillary vein thrombosis: a review

Auteurs : Gary J. Hicken ; F. Michael Ameli

Source :

RBID : PMC:3950057

Abstract

Objective

To study, by literature review, the management of subclavian-axillary vein thrombosis (SAVT) and to make recommendations.

Data sources

The MEDLINE database and cross-referenced articles.

Study selection

Key words subclavian-axillary vein thrombosis, venous thrombosis, Paget–Schroetter syndrome, anticoagulation, and thrombolysis were used to extract articles related to SAVT.

Data extraction

Independent extraction of articles by 2 observers.

Data synthesis

Although numerous studies are available in the literature, they vary widely in their patient selection, treatment methods, follow-up and conclusions. As such, the management of patients with SAVT remains controversial.

Conclusions

Anticoagulation remains the initial treatment of choice for acute SAVT although there is definitely a role for thrombolysis and surgery in selected cases. Surgical intervention should be reserved for patients in whom there is a specific indication. Since chronic symptoms depend largely on the etiology of the disease, treatment should be tailored to address the causative factors. A multicentre, prospective study is necessary to evaluate the optimum management strategies for patients with SAVT.


Url:
PubMed: 9492744
PubMed Central: 3950057

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PMC:3950057

Le document en format XML

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<title>Objective</title>
<p>To study, by literature review, the management of subclavian-axillary vein thrombosis (SAVT) and to make recommendations.</p>
</sec>
<sec sec-type="methods">
<title>Data sources</title>
<p>The MEDLINE database and cross-referenced articles.</p>
</sec>
<sec sec-type="methods">
<title>Study selection</title>
<p>Key words subclavian-axillary vein thrombosis, venous thrombosis, Paget–Schroetter syndrome, anticoagulation, and thrombolysis were used to extract articles related to SAVT.</p>
</sec>
<sec sec-type="methods">
<title>Data extraction</title>
<p>Independent extraction of articles by 2 observers.</p>
</sec>
<sec sec-type="methods">
<title>Data synthesis</title>
<p>Although numerous studies are available in the literature, they vary widely in their patient selection, treatment methods, follow-up and conclusions. As such, the management of patients with SAVT remains controversial.</p>
</sec>
<sec sec-type="conclusions">
<title>Conclusions</title>
<p>Anticoagulation remains the initial treatment of choice for acute SAVT although there is definitely a role for thrombolysis and surgery in selected cases. Surgical intervention should be reserved for patients in whom there is a specific indication. Since chronic symptoms depend largely on the etiology of the disease, treatment should be tailored to address the causative factors. A multicentre, prospective study is necessary to evaluate the optimum management strategies for patients with SAVT.</p>
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