Some morphological aspects of Wuchereria bancrofti uterus after treatment with diethylcarbamazine.
Identifieur interne : 007E74 ( Main/Curation ); précédent : 007E73; suivant : 007E75Some morphological aspects of Wuchereria bancrofti uterus after treatment with diethylcarbamazine.
Auteurs : Christina Alves Peixoto [Brésil]Source :
- Micron (Oxford, England : 1993) [ 0968-4328 ] ; 2005.
Descripteurs français
- KwdFr :
- Animaux, Diéthylcarbamazine (usage thérapeutique), Femelle, Filaricides (usage thérapeutique), Filariose lymphatique (parasitologie), Filariose lymphatique (traitement médicamenteux), Humains, Microfilaria (), Microfilaria (ultrastructure), Microscopie confocale, Microscopie électronique, Mâle, Utérus (), Utérus (ultrastructure), Wuchereria bancrofti (), Wuchereria bancrofti (ultrastructure).
- MESH :
- parasitologie : Filariose lymphatique.
- traitement médicamenteux : Filariose lymphatique.
- usage thérapeutique : Diéthylcarbamazine, Filaricides, Microfilaria, Utérus, Wuchereria bancrofti.
- Animaux, Femelle, Humains, Microfilaria, Microscopie confocale, Microscopie électronique, Mâle, Utérus, Wuchereria bancrofti.
English descriptors
- KwdEn :
- Animals, Diethylcarbamazine (therapeutic use), Elephantiasis, Filarial (drug therapy), Elephantiasis, Filarial (parasitology), Female, Filaricides (therapeutic use), Humans, Male, Microfilariae (drug effects), Microfilariae (ultrastructure), Microscopy, Confocal, Microscopy, Electron, Uterus (drug effects), Uterus (ultrastructure), Wuchereria bancrofti (drug effects), Wuchereria bancrofti (ultrastructure).
- MESH :
- chemical , therapeutic use : Diethylcarbamazine, Filaricides.
- drug effects : Microfilariae, Uterus, Wuchereria bancrofti.
- drug therapy : Elephantiasis, Filarial.
- parasitology : Elephantiasis, Filarial.
- ultrastructure : Microfilariae, Uterus, Wuchereria bancrofti.
- Animals, Female, Humans, Male, Microscopy, Confocal, Microscopy, Electron.
Abstract
Confocal and EM analyses revealed that some female Wuchereria bancrofti, obtained from volunteers that received recommended diethylcarbamazine dose regimens, showed few or no embryos. Furthermore, inside the gravid uterus of female W. bancrofti treated with DEC we observed a finely granular, electron-dense material organised as strings of pearls, approximately 70 nm in maximal length surrounding intra-uterine microfilariae and apparently secreted by the embryo. Over the eggshells a similar material was also observed, possibly secreted by the uterine wall. The surface of intra-uterine microfilariae presented a material with identical electron-density to the scattered structures observed inside the egg. Similarly, the sheath of blood microfilariae of W. bancrofti also showed electron-dense projections, with shape and size similar to that observed inside the uterus.
DOI: 10.1016/j.micron.2004.07.002
PubMed: 15582474
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pubmed:15582474Le document en format XML
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50670-420</wicri:regionArea><wicri:noRegion>CEP 50670-420</wicri:noRegion></affiliation></author></analytic><series><title level="j">Micron (Oxford, England : 1993)</title><idno type="ISSN">0968-4328</idno><imprint><date when="2005" type="published">2005</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Diethylcarbamazine (therapeutic use)</term><term>Elephantiasis, Filarial (drug therapy)</term><term>Elephantiasis, Filarial (parasitology)</term><term>Female</term><term>Filaricides (therapeutic use)</term><term>Humans</term><term>Male</term><term>Microfilariae (drug effects)</term><term>Microfilariae (ultrastructure)</term><term>Microscopy, Confocal</term><term>Microscopy, Electron</term><term>Uterus (drug effects)</term><term>Uterus (ultrastructure)</term><term>Wuchereria bancrofti (drug effects)</term><term>Wuchereria bancrofti (ultrastructure)</term></keywords><keywords 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Filarial</term></keywords><keywords scheme="MESH" qualifier="parasitologie" xml:lang="fr"><term>Filariose lymphatique</term></keywords><keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Filariose lymphatique</term></keywords><keywords scheme="MESH" qualifier="ultrastructure" xml:lang="en"><term>Microfilariae</term><term>Uterus</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Diéthylcarbamazine</term><term>Filaricides</term><term>Microfilaria</term><term>Utérus</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Female</term><term>Humans</term><term>Male</term><term>Microscopy, Confocal</term><term>Microscopy, Electron</term></keywords><keywords scheme="MESH" 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Furthermore, inside the gravid uterus of female W. bancrofti treated with DEC we observed a finely granular, electron-dense material organised as strings of pearls, approximately 70 nm in maximal length surrounding intra-uterine microfilariae and apparently secreted by the embryo. Over the eggshells a similar material was also observed, possibly secreted by the uterine wall. The surface of intra-uterine microfilariae presented a material with identical electron-density to the scattered structures observed inside the egg. Similarly, the sheath of blood microfilariae of W. bancrofti also showed electron-dense projections, with shape and size similar to that observed inside the uterus.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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