Axillary dissection in primary breast cancer: variations of the surgical technique and influence on morbidity
Identifieur interne : 004497 ( Main/Curation ); précédent : 004496; suivant : 004498Axillary dissection in primary breast cancer: variations of the surgical technique and influence on morbidity
Auteurs : Sebastian Wojcinski [Allemagne] ; Sirin Nuengsri [Allemagne] ; Peter Hillemanns [Allemagne] ; Werner Schmidt [Allemagne] ; Mustafa Deryal [Allemagne] ; Kubilay Ertan [Allemagne] ; Friedrich Degenhardt [Allemagne]Source :
- Cancer Management and Research [ 1179-1322 ] ; 2012.
Abstract
Lymphedema of the arm is the most common and impairing complication after breast cancer surgery with axillary lymph node dissection (ALND). Our prospective study evaluated the effect of two different surgical techniques for ALND on postoperative morbidity. Patients were scheduled to undergo ALND. Patients in group 1 (n = 17) underwent the most common and standard technique of ALND, which uses sharp dissection of the tissue and subsequent electro-coagulation of bleedings. Patients in group 2 (n = 17) underwent a modified standard technique of ALND with clamping and ligatures of all resection margins. Postoperative wound secretion was quantified and patients were followed up for 6 months to assess long-term morbidity. The variations in surgical technique had no significant influence on the outcome variables. However, patients in group 2 showed a tendency to less wound secretion (713 versus 802 mL;
Url:
DOI: 10.2147/CMAR.S30207
PubMed: 22570566
PubMed Central: 3346198
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :003C51
- to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :003C50
- to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :002B50
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002128
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :002128
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :002128
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :004D56
- to stream Ncbi, to step Curation: Pour aller vers cette notice dans l'étape Curation :004D56
- to stream Ncbi, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :004D56
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :004518
Links to Exploration step
PMC:3346198Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Axillary dissection in primary breast cancer: variations of the surgical technique and influence on morbidity</title><author><name sortKey="Wojcinski, Sebastian" sort="Wojcinski, Sebastian" uniqKey="Wojcinski S" first="Sebastian" last="Wojcinski">Sebastian Wojcinski</name><affiliation wicri:level="1"><nlm:aff id="af1-cmar-4-121">Franziskus Hospital, Department of Obstetrics/Gynecology, Bielefeld, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Franziskus Hospital, Department of Obstetrics/Gynecology, Bielefeld</wicri:regionArea><wicri:noRegion>Bielefeld</wicri:noRegion><wicri:noRegion>Bielefeld</wicri:noRegion><wicri:noRegion>Bielefeld</wicri:noRegion></affiliation></author><author><name sortKey="Nuengsri, Sirin" sort="Nuengsri, Sirin" uniqKey="Nuengsri S" first="Sirin" last="Nuengsri">Sirin Nuengsri</name><affiliation wicri:level="3"><nlm:aff id="af2-cmar-4-121">Karlsruhe Hospital, Department of Internal Medicine, Karlsruhe, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Karlsruhe Hospital, Department of Internal Medicine, Karlsruhe</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Karlsruhe</settlement></placeName></affiliation></author><author><name sortKey="Hillemanns, Peter" sort="Hillemanns, Peter" uniqKey="Hillemanns P" first="Peter" last="Hillemanns">Peter Hillemanns</name><affiliation wicri:level="3"><nlm:aff id="af3-cmar-4-121">Hannover Medical School, Department of Obstetrics/Gynecology, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Hannover Medical School, Department of Obstetrics/Gynecology, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Schmidt, Werner" sort="Schmidt, Werner" uniqKey="Schmidt W" first="Werner" last="Schmidt">Werner Schmidt</name><affiliation wicri:level="1"><nlm:aff id="af4-cmar-4-121">University Hospital of Saarland, Department of Obstetrics/Gynecology, Homburg/Saar, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Hospital of Saarland, Department of Obstetrics/Gynecology, Homburg/Saar</wicri:regionArea><wicri:noRegion>Homburg/Saar</wicri:noRegion><wicri:noRegion>Homburg/Saar</wicri:noRegion><wicri:noRegion>Homburg/Saar</wicri:noRegion></affiliation></author><author><name sortKey="Deryal, Mustafa" sort="Deryal, Mustafa" uniqKey="Deryal M" first="Mustafa" last="Deryal">Mustafa Deryal</name><affiliation wicri:level="3"><nlm:aff id="af5-cmar-4-121">Caritas Hospital Saarbrücken St Theresia, Department of Obstetrics/Gynecology, Saarbrücken, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Caritas Hospital Saarbrücken St Theresia, Department of Obstetrics/Gynecology, Saarbrücken</wicri:regionArea><placeName><region type="land" nuts="2">Sarre (Land)</region><settlement type="city">Sarrebruck</settlement></placeName></affiliation></author><author><name sortKey="Ertan, Kubilay" sort="Ertan, Kubilay" uniqKey="Ertan K" first="Kubilay" last="Ertan">Kubilay Ertan</name><affiliation wicri:level="1"><nlm:aff id="af6-cmar-4-121">Leverkusen Hospital, Department of Obstetrics/Gynecology, Leverkusen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Leverkusen Hospital, Department of Obstetrics/Gynecology, Leverkusen</wicri:regionArea><wicri:noRegion>Leverkusen</wicri:noRegion><wicri:noRegion>Leverkusen</wicri:noRegion><wicri:noRegion>Leverkusen</wicri:noRegion></affiliation></author><author><name sortKey="Degenhardt, Friedrich" sort="Degenhardt, Friedrich" uniqKey="Degenhardt F" first="Friedrich" last="Degenhardt">Friedrich Degenhardt</name><affiliation wicri:level="1"><nlm:aff id="af1-cmar-4-121">Franziskus Hospital, Department of Obstetrics/Gynecology, Bielefeld, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Franziskus Hospital, Department of Obstetrics/Gynecology, Bielefeld</wicri:regionArea><wicri:noRegion>Bielefeld</wicri:noRegion><wicri:noRegion>Bielefeld</wicri:noRegion><wicri:noRegion>Bielefeld</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22570566</idno><idno type="pmc">3346198</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346198</idno><idno type="RBID">PMC:3346198</idno><idno type="doi">10.2147/CMAR.S30207</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">003C51</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003C51</idno><idno type="wicri:Area/Pmc/Curation">003C50</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003C50</idno><idno type="wicri:Area/Pmc/Checkpoint">002B50</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002B50</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">002128</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002128</idno><idno type="wicri:Area/PubMed/Curation">002128</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002128</idno><idno type="wicri:Area/PubMed/Checkpoint">002128</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002128</idno><idno type="wicri:Area/Ncbi/Merge">004D56</idno><idno type="wicri:Area/Ncbi/Curation">004D56</idno><idno type="wicri:Area/Ncbi/Checkpoint">004D56</idno><idno type="wicri:Area/Main/Merge">004518</idno><idno type="wicri:Area/Main/Curation">004497</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Axillary dissection in primary breast cancer: variations of the surgical technique and influence on morbidity</title><author><name sortKey="Wojcinski, Sebastian" sort="Wojcinski, Sebastian" uniqKey="Wojcinski S" first="Sebastian" last="Wojcinski">Sebastian Wojcinski</name><affiliation wicri:level="1"><nlm:aff id="af1-cmar-4-121">Franziskus Hospital, Department of Obstetrics/Gynecology, Bielefeld, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Franziskus Hospital, Department of Obstetrics/Gynecology, Bielefeld</wicri:regionArea><wicri:noRegion>Bielefeld</wicri:noRegion><wicri:noRegion>Bielefeld</wicri:noRegion><wicri:noRegion>Bielefeld</wicri:noRegion></affiliation></author><author><name sortKey="Nuengsri, Sirin" sort="Nuengsri, Sirin" uniqKey="Nuengsri S" first="Sirin" last="Nuengsri">Sirin Nuengsri</name><affiliation wicri:level="3"><nlm:aff id="af2-cmar-4-121">Karlsruhe Hospital, Department of Internal Medicine, Karlsruhe, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Karlsruhe Hospital, Department of Internal Medicine, Karlsruhe</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Karlsruhe</settlement></placeName></affiliation></author><author><name sortKey="Hillemanns, Peter" sort="Hillemanns, Peter" uniqKey="Hillemanns P" first="Peter" last="Hillemanns">Peter Hillemanns</name><affiliation wicri:level="3"><nlm:aff id="af3-cmar-4-121">Hannover Medical School, Department of Obstetrics/Gynecology, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Hannover Medical School, Department of Obstetrics/Gynecology, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Schmidt, Werner" sort="Schmidt, Werner" uniqKey="Schmidt W" first="Werner" last="Schmidt">Werner Schmidt</name><affiliation wicri:level="1"><nlm:aff id="af4-cmar-4-121">University Hospital of Saarland, Department of Obstetrics/Gynecology, Homburg/Saar, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Hospital of Saarland, Department of Obstetrics/Gynecology, Homburg/Saar</wicri:regionArea><wicri:noRegion>Homburg/Saar</wicri:noRegion><wicri:noRegion>Homburg/Saar</wicri:noRegion><wicri:noRegion>Homburg/Saar</wicri:noRegion></affiliation></author><author><name sortKey="Deryal, Mustafa" sort="Deryal, Mustafa" uniqKey="Deryal M" first="Mustafa" last="Deryal">Mustafa Deryal</name><affiliation wicri:level="3"><nlm:aff id="af5-cmar-4-121">Caritas Hospital Saarbrücken St Theresia, Department of Obstetrics/Gynecology, Saarbrücken, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Caritas Hospital Saarbrücken St Theresia, Department of Obstetrics/Gynecology, Saarbrücken</wicri:regionArea><placeName><region type="land" nuts="2">Sarre (Land)</region><settlement type="city">Sarrebruck</settlement></placeName></affiliation></author><author><name sortKey="Ertan, Kubilay" sort="Ertan, Kubilay" uniqKey="Ertan K" first="Kubilay" last="Ertan">Kubilay Ertan</name><affiliation wicri:level="1"><nlm:aff id="af6-cmar-4-121">Leverkusen Hospital, Department of Obstetrics/Gynecology, Leverkusen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Leverkusen Hospital, Department of Obstetrics/Gynecology, Leverkusen</wicri:regionArea><wicri:noRegion>Leverkusen</wicri:noRegion><wicri:noRegion>Leverkusen</wicri:noRegion><wicri:noRegion>Leverkusen</wicri:noRegion></affiliation></author><author><name sortKey="Degenhardt, Friedrich" sort="Degenhardt, Friedrich" uniqKey="Degenhardt F" first="Friedrich" last="Degenhardt">Friedrich Degenhardt</name><affiliation wicri:level="1"><nlm:aff id="af1-cmar-4-121">Franziskus Hospital, Department of Obstetrics/Gynecology, Bielefeld, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Franziskus Hospital, Department of Obstetrics/Gynecology, Bielefeld</wicri:regionArea><wicri:noRegion>Bielefeld</wicri:noRegion><wicri:noRegion>Bielefeld</wicri:noRegion><wicri:noRegion>Bielefeld</wicri:noRegion></affiliation></author></analytic><series><title level="j">Cancer Management and Research</title><idno type="eISSN">1179-1322</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Lymphedema of the arm is the most common and impairing complication after breast cancer surgery with axillary lymph node dissection (ALND). Our prospective study evaluated the effect of two different surgical techniques for ALND on postoperative morbidity. Patients were scheduled to undergo ALND. Patients in group 1 (n = 17) underwent the most common and standard technique of ALND, which uses sharp dissection of the tissue and subsequent electro-coagulation of bleedings. Patients in group 2 (n = 17) underwent a modified standard technique of ALND with clamping and ligatures of all resection margins. Postoperative wound secretion was quantified and patients were followed up for 6 months to assess long-term morbidity. The variations in surgical technique had no significant influence on the outcome variables. However, patients in group 2 showed a tendency to less wound secretion (713 versus 802 mL; <italic>P</italic> = nonsignificant), a decreased rate of immediate postoperative seromas (11.8 versus 23.5%; <italic>P</italic> = nonsignificant) and less lymphedema after 3 months (29.4 versus 41.2%; <italic>P</italic> = nonsignificant). Moreover, the number of resected lymph nodes correlated with the total amount of drained fluid (<italic>P</italic> = 0.006), the duration of the drain (<italic>P</italic> = 0.015), and the risk for the development of lymphedema after 3 months (<italic>P</italic> = 0.016). The described variations in surgical technique had no influence on the outcomes of the patients. The number of resected axillary lymph nodes remains the most important risk factor for treatment-related morbidity. Therefore, a well-balanced choice of the extent of the axillary dissection should be the surgeon’s main concern.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Wang, Z" uniqKey="Wang Z">Z Wang</name></author><author><name sortKey="Wu, Lc" uniqKey="Wu L">LC Wu</name></author><author><name sortKey="Chen, Jq" uniqKey="Chen J">JQ Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schijven, Mp" uniqKey="Schijven M">MP Schijven</name></author><author><name sortKey="Vingerhoets, Aj" uniqKey="Vingerhoets A">AJ Vingerhoets</name></author><author><name sortKey="Rutten, Hj" uniqKey="Rutten H">HJ Rutten</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mathew, J" uniqKey="Mathew J">J Mathew</name></author><author><name sortKey="Barthelmes, L" uniqKey="Barthelmes L">L Barthelmes</name></author><author><name sortKey="Neminathan, S" uniqKey="Neminathan S">S Neminathan</name></author><author><name sortKey="Crawford, D" uniqKey="Crawford D">D Crawford</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kahtcheressian, Jl" uniqKey="Kahtcheressian J">JL Kahtcheressian</name></author><author><name sortKey="Wolff, Ac" uniqKey="Wolff A">AC Wolff</name></author><author><name sortKey="Smith, Tj" uniqKey="Smith T">TJ Smith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kocak, Z" uniqKey="Kocak Z">Z Kocak</name></author><author><name sortKey="Overgaard, J" uniqKey="Overgaard J">J Overgaard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuehn, T" uniqKey="Kuehn T">T Kuehn</name></author><author><name sortKey="Bembenek, A" uniqKey="Bembenek A">A Bembenek</name></author><author><name sortKey="Decker, T" uniqKey="Decker T">T Decker</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Lucci, A" uniqKey="Lucci A">A Lucci</name></author><author><name sortKey="Mccall, Lm" uniqKey="Mccall L">LM McCall</name></author><author><name sortKey="Beitsch, Pd" uniqKey="Beitsch P">PD Beitsch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zuber, M" uniqKey="Zuber M">M Zuber</name></author><author><name sortKey="Oertli, D" uniqKey="Oertli D">D Oertli</name></author><author><name sortKey="Marti, Wr" uniqKey="Marti W">WR Marti</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Redon, H" uniqKey="Redon H">H Redon</name></author><author><name sortKey="Jost, A" uniqKey="Jost A">A Jost</name></author><author><name sortKey="Troques, A" uniqKey="Troques A">A Troques</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cheville, Al" uniqKey="Cheville A">AL Cheville</name></author><author><name sortKey="Mcgarvey, Cl" uniqKey="Mcgarvey C">CL McGarvey</name></author><author><name sortKey="Petrek, Ja" uniqKey="Petrek J">JA Petrek</name></author><author><name sortKey="Russo, Sa" uniqKey="Russo S">SA Russo</name></author><author><name sortKey="Thiadens, Sr" uniqKey="Thiadens S">SR Thiadens</name></author><author><name sortKey="Taylor, Me" uniqKey="Taylor M">ME Taylor</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pavy, Jj" uniqKey="Pavy J">JJ Pavy</name></author><author><name sortKey="Denekamp, J" uniqKey="Denekamp J">J Denekamp</name></author><author><name sortKey="Letschert, J" uniqKey="Letschert J">J Letschert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Agrawal, A" uniqKey="Agrawal A">A Agrawal</name></author><author><name sortKey="Ayatunde, Aa" uniqKey="Ayatunde A">AA Ayatunde</name></author><author><name sortKey="Cheung, Kl" uniqKey="Cheung K">KL Cheung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bonnema, J" uniqKey="Bonnema J">J Bonnema</name></author><author><name sortKey="Ligtenstein, Da" uniqKey="Ligtenstein D">DA Ligtenstein</name></author><author><name sortKey="Wiggers, T" uniqKey="Wiggers T">T Wiggers</name></author><author><name sortKey="Van Geel, An" uniqKey="Van Geel A">AN van Geel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tsai, Rj" uniqKey="Tsai R">RJ Tsai</name></author><author><name sortKey="Dennis, Lk" uniqKey="Dennis L">LK Dennis</name></author><author><name sortKey="Lynch, Cf" uniqKey="Lynch C">CF Lynch</name></author><author><name sortKey="Snetselaar, Lg" uniqKey="Snetselaar L">LG Snetselaar</name></author><author><name sortKey="Zamba, Gk" uniqKey="Zamba G">GK Zamba</name></author><author><name sortKey="Scott Conner, C" uniqKey="Scott Conner C">C Scott-Conner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Erickson, Vs" uniqKey="Erickson V">VS Erickson</name></author><author><name sortKey="Pearson, Ml" uniqKey="Pearson M">ML Pearson</name></author><author><name sortKey="Ganz, Pa" uniqKey="Ganz P">PA Ganz</name></author><author><name sortKey="Adams, J" uniqKey="Adams J">J Adams</name></author><author><name sortKey="Kahn, Kl" uniqKey="Kahn K">KL Kahn</name></author></analytic></biblStruct></listBibl></div1></back></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004497 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 004497 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Curation
|type= RBID
|clé= PMC:3346198
|texte= Axillary dissection in primary breast cancer: variations of the surgical technique and influence on morbidity
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Curation/RBID.i -Sk "pubmed:22570566" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Curation/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |