The pathophysiology of lymphedema - 2012.
Identifieur interne : 003E05 ( Main/Curation ); précédent : 003E04; suivant : 003E06The pathophysiology of lymphedema - 2012.
Auteurs : W L Olszewski [Pologne]Source :
- Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... [ 1439-3980 ] ; 2012.
Descripteurs français
- KwdFr :
- Anastomose chirurgicale (), Bras (), Bras (anatomopathologie), Cicatrisation de plaie (physiologie), Humains, Immunité cellulaire (physiologie), Lymphe (physiologie), Lymphoedème (anatomopathologie), Lymphoedème (physiopathologie), Lymphoedème (étiologie), Maladies lymphatiques (), Maladies lymphatiques (anatomopathologie), Maladies lymphatiques (physiopathologie), Microchirurgie (), Tissu lymphoïde (), Tissu lymphoïde (anatomopathologie), Tissu lymphoïde (physiopathologie), Vaisseaux lymphatiques (), Vaisseaux lymphatiques (anatomopathologie).
- MESH :
- anatomopathologie : Bras, Lymphoedème, Maladies lymphatiques, Tissu lymphoïde, Vaisseaux lymphatiques.
- physiologie : Cicatrisation de plaie, Immunité cellulaire, Lymphe.
- physiopathologie : Lymphoedème, Maladies lymphatiques, Tissu lymphoïde.
- étiologie : Lymphoedème.
- Anastomose chirurgicale, Bras, Humains, Maladies lymphatiques, Microchirurgie, Tissu lymphoïde, Vaisseaux lymphatiques.
English descriptors
- KwdEn :
- Anastomosis, Surgical (methods), Arm (pathology), Arm (surgery), Humans, Immunity, Cellular (physiology), Lymph (physiology), Lymphatic Diseases (pathology), Lymphatic Diseases (physiopathology), Lymphatic Diseases (surgery), Lymphatic Vessels (pathology), Lymphatic Vessels (surgery), Lymphedema (etiology), Lymphedema (pathology), Lymphedema (physiopathology), Lymphoid Tissue (pathology), Lymphoid Tissue (physiopathology), Lymphoid Tissue (surgery), Microsurgery (methods), Wound Healing (physiology).
- MESH :
- etiology : Lymphedema.
- methods : Anastomosis, Surgical, Microsurgery.
- pathology : Arm, Lymphatic Diseases, Lymphatic Vessels, Lymphedema, Lymphoid Tissue.
- physiology : Immunity, Cellular, Lymph, Wound Healing.
- physiopathology : Lymphatic Diseases, Lymphedema, Lymphoid Tissue.
- surgery : Arm, Lymphatic Diseases, Lymphatic Vessels, Lymphoid Tissue.
- Humans.
Abstract
Lymphedema of the limbs has become a frequent pathological condition after soft tissue inflammation, trauma, removal of lymph nodes in cancer and long-lasting ulcerations. Lymphatics draining the diseased tissues become occluded. Microsurgery helps in the formation of anastomoses and collaterals bypassing the obstruction site. Surgeons operating on the lymphatics should be aware of the tissue fluid/lymph formation mechanism, hydraulics of tissue fluid/lymph, tissue metabolism and waste material utilization, immune function in terms of elimination of microbial and tumor antigens and raising tolerance to own tissue antigens of injured tissues necessary for wound healing as well as classification of diseases of lymphatics. In this review we present the actual definition of the lymphatic system, how it is changed in lymphedema, and, in particular, tissue fluid/lymph biochemistry, pressure and flow, histopathology and tissue fluid location, and finally how to manage the most common complication dermato-lymphangioadenitis. Detailed knowledge of the anatomy of upper limb limphaties should prevent their damage and loss of function.
DOI: 10.1055/s-0032-1323737
PubMed: 23283812
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pubmed:23283812Le document en format XML
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<front><div type="abstract" xml:lang="en">Lymphedema of the limbs has become a frequent pathological condition after soft tissue inflammation, trauma, removal of lymph nodes in cancer and long-lasting ulcerations. Lymphatics draining the diseased tissues become occluded. Microsurgery helps in the formation of anastomoses and collaterals bypassing the obstruction site. Surgeons operating on the lymphatics should be aware of the tissue fluid/lymph formation mechanism, hydraulics of tissue fluid/lymph, tissue metabolism and waste material utilization, immune function in terms of elimination of microbial and tumor antigens and raising tolerance to own tissue antigens of injured tissues necessary for wound healing as well as classification of diseases of lymphatics. In this review we present the actual definition of the lymphatic system, how it is changed in lymphedema, and, in particular, tissue fluid/lymph biochemistry, pressure and flow, histopathology and tissue fluid location, and finally how to manage the most common complication dermato-lymphangioadenitis. Detailed knowledge of the anatomy of upper limb limphaties should prevent their damage and loss of function.</div>
</front>
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