Orofacial granulomatosis: three case reports illustrating the spectrum of disease and overlap with Crohn's disease
Identifieur interne : 003A95 ( Main/Curation ); précédent : 003A94; suivant : 003A96Orofacial granulomatosis: three case reports illustrating the spectrum of disease and overlap with Crohn's disease
Auteurs : V. M. Smith [Royaume-Uni] ; R. Murphy [Royaume-Uni]Source :
- Clinical and Experimental Dermatology [ 0307-6938 ] ; 2013-01.
Abstract
We report three cases of orofacial granulomatosis (OFG) to illustrate the spectrum of this disease, and to discuss the appropriate management steps, consider its overlap with Crohn's disease (CD) and raise its awareness among paediatric dermatologists. The term ‘orofacial granulomatosis’ was first used in 1985 to describe granulomas in the orofacial region in the absence of any recognized systemic condition. It is uncommon but becoming increasingly recognized in children. The clinical features of the disease may vary greatly, and often present with subtle changes that can be missed. There is a debate about whether OFG exists as a separate condition or whether it is an oral feature of CD, as some patients go on to develop CD several years later. Identifying those most at risk is important, as ongoing investigations may be necessary. The three cases presented in this series illustrate the range of disease signs and symptoms, and the investigations required.
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DOI: 10.1111/j.1365-2230.2012.04377.x
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