Detection of Serum IgG Antibodies Specific for Wolbachia Surface Protein in Rhesus Monkeys Infected with Brugia malayi
Identifieur interne : 003251 ( Istex/Curation ); précédent : 003250; suivant : 003252Detection of Serum IgG Antibodies Specific for Wolbachia Surface Protein in Rhesus Monkeys Infected with Brugia malayi
Auteurs : George A. Punkosdy [Géorgie (pays)] ; Vida A. Dennis [États-Unis] ; Barbara L. Lasater [États-Unis] ; George Tzertzinis [États-Unis] ; Jeremy M. Foster [États-Unis] ; Patrick J. Lammie [Géorgie (pays)]Source :
- The Journal of Infectious Diseases [ 0022-1899 ] ; 2001-08-01.
Abstract
The mechanism of lymphedema development in individuals with lymphatic filariasis is presently poorly understood. To investigate whether Wolbachia, symbiotic bacteria living within filarial nematodes, may be involved in disease progression, Wolbachia‐specific immune responses were assayed in a group of Brugia malayi–infected rhesus monkeys. Serum IgG antibodies specific for a major Wolbachia surface protein (WSP) were detected in 2 of 12 infected monkeys. It is interesting that both of these monkeys developed lymphedema after becoming amicrofilaremic. WSP‐specific antibody responses were temporally associated with increases in antifilarial IgG1 antibodies as well as lymphedema development. These findings suggest that Wolbachia may be important in understanding disease caused by filarial worms.
Url:
DOI: 10.1086/322023
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :003251
Links to Exploration step
ISTEX:6C00FDF13A2963AABFD4B1931452EDEB724EF92BLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Detection of Serum IgG Antibodies Specific for Wolbachia Surface Protein in Rhesus Monkeys Infected with Brugia malayi</title><author><name sortKey="Punkosdy, George A" sort="Punkosdy, George A" uniqKey="Punkosdy G" first="George A." last="Punkosdy">George A. Punkosdy</name><affiliation><mods:affiliation>Department of Cellular Biology, University of Georgia, Athens, and</mods:affiliation><wicri:noCountry code="subField">and</wicri:noCountry></affiliation><affiliation wicri:level="1"><mods:affiliation>Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</mods:affiliation><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Dennis, Vida A" sort="Dennis, Vida A" uniqKey="Dennis V" first="Vida A." last="Dennis">Vida A. Dennis</name><affiliation wicri:level="2"><mods:affiliation>Department of Parasitology, Tulane Regional Primate Research Center, Tulane University School of Medicine, Covington, Louisiana</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Louisiane</region></placeName><wicri:cityArea>Department of Parasitology, Tulane Regional Primate Research Center, Tulane University School of Medicine, Covington</wicri:cityArea></affiliation></author><author><name sortKey="Lasater, Barbara L" sort="Lasater, Barbara L" uniqKey="Lasater B" first="Barbara L." last="Lasater">Barbara L. Lasater</name><affiliation wicri:level="2"><mods:affiliation>Department of Parasitology, Tulane Regional Primate Research Center, Tulane University School of Medicine, Covington, Louisiana</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Louisiane</region></placeName><wicri:cityArea>Department of Parasitology, Tulane Regional Primate Research Center, Tulane University School of Medicine, Covington</wicri:cityArea></affiliation></author><author><name sortKey="Tzertzinis, George" sort="Tzertzinis, George" uniqKey="Tzertzinis G" first="George" last="Tzertzinis">George Tzertzinis</name><affiliation wicri:level="2"><mods:affiliation>New England Biolabs, Beverly, Massachusetts</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>New England Biolabs, Beverly</wicri:cityArea></affiliation></author><author><name sortKey="Foster, Jeremy M" sort="Foster, Jeremy M" uniqKey="Foster J" first="Jeremy M." last="Foster">Jeremy M. Foster</name><affiliation wicri:level="2"><mods:affiliation>New England Biolabs, Beverly, Massachusetts</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>New England Biolabs, Beverly</wicri:cityArea></affiliation></author><author><name sortKey="Lammie, Patrick J" sort="Lammie, Patrick J" uniqKey="Lammie P" first="Patrick J." last="Lammie">Patrick J. Lammie</name><affiliation wicri:level="1"><mods:affiliation>Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</mods:affiliation><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation><affiliation><mods:affiliation>E-mail: pjl1@cdc.gov</mods:affiliation><wicri:noCountry code="no comma">E-mail: pjl1@cdc.gov</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:6C00FDF13A2963AABFD4B1931452EDEB724EF92B</idno><date when="2001" year="2001">2001</date><idno type="doi">10.1086/322023</idno><idno type="url">https://api.istex.fr/document/6C00FDF13A2963AABFD4B1931452EDEB724EF92B/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">003251</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">003251</idno><idno type="wicri:Area/Istex/Curation">003251</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Detection of Serum IgG Antibodies Specific for Wolbachia Surface Protein in Rhesus Monkeys Infected with Brugia malayi</title><author><name sortKey="Punkosdy, George A" sort="Punkosdy, George A" uniqKey="Punkosdy G" first="George A." last="Punkosdy">George A. Punkosdy</name><affiliation><mods:affiliation>Department of Cellular Biology, University of Georgia, Athens, and</mods:affiliation></affiliation><affiliation wicri:level="1"><mods:affiliation>Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</mods:affiliation><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation></author><author><name sortKey="Dennis, Vida A" sort="Dennis, Vida A" uniqKey="Dennis V" first="Vida A." last="Dennis">Vida A. Dennis</name><affiliation wicri:level="2"><mods:affiliation>Department of Parasitology, Tulane Regional Primate Research Center, Tulane University School of Medicine, Covington, Louisiana</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Louisiane</region></placeName><wicri:cityArea>Department of Parasitology, Tulane Regional Primate Research Center, Tulane University School of Medicine, Covington</wicri:cityArea></affiliation></author><author><name sortKey="Lasater, Barbara L" sort="Lasater, Barbara L" uniqKey="Lasater B" first="Barbara L." last="Lasater">Barbara L. Lasater</name><affiliation wicri:level="2"><mods:affiliation>Department of Parasitology, Tulane Regional Primate Research Center, Tulane University School of Medicine, Covington, Louisiana</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Louisiane</region></placeName><wicri:cityArea>Department of Parasitology, Tulane Regional Primate Research Center, Tulane University School of Medicine, Covington</wicri:cityArea></affiliation></author><author><name sortKey="Tzertzinis, George" sort="Tzertzinis, George" uniqKey="Tzertzinis G" first="George" last="Tzertzinis">George Tzertzinis</name><affiliation wicri:level="2"><mods:affiliation>New England Biolabs, Beverly, Massachusetts</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>New England Biolabs, Beverly</wicri:cityArea></affiliation></author><author><name sortKey="Foster, Jeremy M" sort="Foster, Jeremy M" uniqKey="Foster J" first="Jeremy M." last="Foster">Jeremy M. Foster</name><affiliation wicri:level="2"><mods:affiliation>New England Biolabs, Beverly, Massachusetts</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>New England Biolabs, Beverly</wicri:cityArea></affiliation></author><author><name sortKey="Lammie, Patrick J" sort="Lammie, Patrick J" uniqKey="Lammie P" first="Patrick J." last="Lammie">Patrick J. Lammie</name><affiliation wicri:level="1"><mods:affiliation>Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia</mods:affiliation><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta</wicri:regionArea></affiliation><affiliation><mods:affiliation>E-mail: pjl1@cdc.gov</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">The Journal of Infectious Diseases</title><title level="j" type="abbrev">The Journal of Infectious Diseases</title><idno type="ISSN">0022-1899</idno><idno type="eISSN">1537-6613</idno><imprint><publisher>University of Chicago Press</publisher><date type="published" when="2001-08-01">2001-08-01</date><biblScope unit="volume">184</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="385">385</biblScope><biblScope unit="page" to="389">389</biblScope></imprint><idno type="ISSN">0022-1899</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0022-1899</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">The mechanism of lymphedema development in individuals with lymphatic filariasis is presently poorly understood. To investigate whether Wolbachia, symbiotic bacteria living within filarial nematodes, may be involved in disease progression, Wolbachia‐specific immune responses were assayed in a group of Brugia malayi–infected rhesus monkeys. Serum IgG antibodies specific for a major Wolbachia surface protein (WSP) were detected in 2 of 12 infected monkeys. It is interesting that both of these monkeys developed lymphedema after becoming amicrofilaremic. WSP‐specific antibody responses were temporally associated with increases in antifilarial IgG1 antibodies as well as lymphedema development. These findings suggest that Wolbachia may be important in understanding disease caused by filarial worms.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Istex/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003251 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Curation/biblio.hfd -nk 003251 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Istex
|étape= Curation
|type= RBID
|clé= ISTEX:6C00FDF13A2963AABFD4B1931452EDEB724EF92B
|texte= Detection of Serum IgG Antibodies Specific for Wolbachia Surface Protein in Rhesus Monkeys Infected with Brugia malayi
}}
| This area was generated with Dilib version V0.6.31. |  |