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Proteomics analysis of serous fluids and effusions: Pleural, pericardial, and peritoneal

Identifieur interne : 003197 ( Istex/Curation ); précédent : 003196; suivant : 003198

Proteomics analysis of serous fluids and effusions: Pleural, pericardial, and peritoneal

Auteurs : Yu-Chang Tyan [Taïwan] ; Pao-Chi Liao [Taïwan]

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RBID : ISTEX:6AD8E916CF1D28EB78036C2AFC387EC0CA3FDCC5

Abstract

Serous body fluids are normally present in small amounts in the cavities lined by serous membranes, and effusions are the term usually used to represent an excess of these fluids. Thus, any changes in the effusions may accurately reflect various pathological processes. In this review, we will introduce the present status of effusion analysis. Proteomics allows the global study of protein expression and offers a comprehensive view to analyze effusion proteins at a system level. It deals with the study of proteins, their structures, localizations, PTM, functions, and interactions with other proteins. This paper reviews the variety of analytical methods that have been used for the analysis of effusions. The proteins expressed in effusions, which have been identified by proteomics methods are discussed.

Url:
DOI: 10.1002/prca.200700036

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ISTEX:6AD8E916CF1D28EB78036C2AFC387EC0CA3FDCC5

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