Older Breast Cancer Survivors: Factors Associated with Self‐reported Symptoms of Persistent Lymphedema Over 7 years of Follow‐up
Identifieur interne : 007096 ( Istex/Corpus ); précédent : 007095; suivant : 007097Older Breast Cancer Survivors: Factors Associated with Self‐reported Symptoms of Persistent Lymphedema Over 7 years of Follow‐up
Auteurs : Kerri M. Clough-Gorr ; Patricia A. Ganz ; Rebecca A. SillimanSource :
- The Breast Journal [ 1075-122X ] ; 2010-03.
Abstract
Abstract: Lymphedema of the arm is a common complication of breast cancer with symptoms that can persist over long periods of time. For older women (over 50% of breast cancer cases) it means living with the potential for long‐term complications of persistent lymphedema in conjunction with the common diseases and disabilities of aging over survivorship. We identified women ≥65 years diagnosed with primary stage I–IIIA breast cancer. Data were collected over 7 years of follow‐up from consenting patients’ medical records and telephone interviews. Data collected included self‐reported symptoms of persistent lymphedema, breast cancer characteristics, and selected sociodemographic and health‐related characteristics. The overall prevalence of symptoms of persistent lymphedema was 36% over 7 years of follow‐up. Having stage II or III (OR = 1.77, 95% CI: 1.07–2.93) breast cancer and having a BMI >30 (OR = 3.04, 95% CI: 1.69–5.45) were statistically significantly predictive of symptoms of persistent lymphedema. Women ≥80 years were less likely to report symptoms of persistent lymphedema when compared to younger women (OR = 0.44, 95% CI: 0.18–0.95). Women with symptoms of persistent lymphedema consistently reported worse general mental health and physical function. Symptoms of persistent lymphedema were common in this population of older breast cancer survivors and had a noticeable effect on both physical function and general mental health. Our findings provide evidence of the impact of symptoms of persistent lymphedema on the quality of survivorship of older women. Clinical and research efforts focused on risk factors for symptoms of persistent lymphedema in older breast cancer survivors may lead to preventative and therapeutic measures that help maintain their health and well‐being over increasing periods of survivorship.
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DOI: 10.1111/j.1524-4741.2009.00878.x
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Clough-Gorr</name><affiliation><mods:affiliation>Geriatrics Section, Boston University Schools of Medicine and Public Health, Boston, Massachusetts</mods:affiliation></affiliation><affiliation><mods:affiliation>Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Geriatrics, Inselspital University of Bern Hospital, Bern, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Ganz, Patricia A" sort="Ganz, Patricia A" uniqKey="Ganz P" first="Patricia A." last="Ganz">Patricia A. 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Silliman</name><affiliation><mods:affiliation>Geriatrics Section, Boston University Schools of Medicine and Public Health, Boston, Massachusetts</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">The Breast Journal</title><title level="j" type="alt">BREAST JOURNAL</title><idno type="ISSN">1075-122X</idno><idno type="eISSN">1524-4741</idno><imprint><biblScope unit="vol">16</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="147">147</biblScope><biblScope unit="page" to="155">155</biblScope><biblScope unit="page-count">9</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2010-03">2010-03</date></imprint><idno type="ISSN">1075-122X</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1075-122X</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">Abstract: Lymphedema of the arm is a common complication of breast cancer with symptoms that can persist over long periods of time. For older women (over 50% of breast cancer cases) it means living with the potential for long‐term complications of persistent lymphedema in conjunction with the common diseases and disabilities of aging over survivorship. We identified women ≥65 years diagnosed with primary stage I–IIIA breast cancer. Data were collected over 7 years of follow‐up from consenting patients’ medical records and telephone interviews. Data collected included self‐reported symptoms of persistent lymphedema, breast cancer characteristics, and selected sociodemographic and health‐related characteristics. The overall prevalence of symptoms of persistent lymphedema was 36% over 7 years of follow‐up. Having stage II or III (OR = 1.77, 95% CI: 1.07–2.93) breast cancer and having a BMI >30 (OR = 3.04, 95% CI: 1.69–5.45) were statistically significantly predictive of symptoms of persistent lymphedema. Women ≥80 years were less likely to report symptoms of persistent lymphedema when compared to younger women (OR = 0.44, 95% CI: 0.18–0.95). Women with symptoms of persistent lymphedema consistently reported worse general mental health and physical function. Symptoms of persistent lymphedema were common in this population of older breast cancer survivors and had a noticeable effect on both physical function and general mental health. Our findings provide evidence of the impact of symptoms of persistent lymphedema on the quality of survivorship of older women. Clinical and research efforts focused on risk factors for symptoms of persistent lymphedema in older breast cancer survivors may lead to preventative and therapeutic measures that help maintain their health and well‐being over increasing periods of survivorship.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>lymphedema</json:string><json:string>sopl</json:string><json:string>breast cancer</json:string><json:string>persistent lymphedema</json:string><json:string>survivor</json:string><json:string>older breast cancer survivors</json:string><json:string>alnd</json:string><json:string>oncol</json:string><json:string>clin</json:string><json:string>mhi5</json:string><json:string>older women</json:string><json:string>axillary</json:string><json:string>predictor</json:string><json:string>node</json:string><json:string>baseline</json:string><json:string>morbidity</json:string><json:string>surg</json:string><json:string>ganz</json:string><json:string>clin oncol</json:string><json:string>risk factors</json:string><json:string>sociodemographic</json:string><json:string>mental health</json:string><json:string>physical function</json:string><json:string>breast cancer treatment</json:string><json:string>breast cancer patients</json:string><json:string>survivorship</json:string><json:string>tamoxifen</json:string><json:string>axillary lymph node dissection</json:string><json:string>breast cancer survivors</json:string><json:string>transient lymphedema</json:string><json:string>longitudinal study</json:string><json:string>mental health index</json:string><json:string>physical function index</json:string><json:string>breast</json:string><json:string>symptom</json:string><json:string>body mass index</json:string><json:string>baseline population</json:string><json:string>breast lymphedema</json:string><json:string>older survivors</json:string><json:string>psychological distress</json:string><json:string>analytic population</json:string><json:string>therapy mastectomy</json:string><json:string>sentinel lymph node biopsy</json:string><json:string>small numbers</json:string><json:string>baseline predictors</json:string><json:string>high school</json:string><json:string>mhi5 scores</json:string><json:string>older breast cancer survivors symptoms</json:string><json:string>functional impairment</json:string><json:string>national cancer institute</json:string><json:string>american cancer society</json:string><json:string>rhode island</json:string><json:string>study population</json:string><json:string>independent variables</json:string><json:string>therapeutic measures</json:string><json:string>report sopl</json:string><json:string>cancer</json:string></teeft></keywords><author><json:item><name>Kerri M. 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For older women (over 50% of breast cancer cases) it means living with the potential for long‐term complications of persistent lymphedema in conjunction with the common diseases and disabilities of aging over survivorship. We identified women ≥65 years diagnosed with primary stage I–IIIA breast cancer. Data were collected over 7 years of follow‐up from consenting patients’ medical records and telephone interviews. Data collected included self‐reported symptoms of persistent lymphedema, breast cancer characteristics, and selected sociodemographic and health‐related characteristics. The overall prevalence of symptoms of persistent lymphedema was 36% over 7 years of follow‐up. Having stage II or III (OR = 1.77, 95% CI: 1.07–2.93) breast cancer and having a BMI >30 (OR = 3.04, 95% CI: 1.69–5.45) were statistically significantly predictive of symptoms of persistent lymphedema. Women ≥80 years were less likely to report symptoms of persistent lymphedema when compared to younger women (OR = 0.44, 95% CI: 0.18–0.95). Women with symptoms of persistent lymphedema consistently reported worse general mental health and physical function. Symptoms of persistent lymphedema were common in this population of older breast cancer survivors and had a noticeable effect on both physical function and general mental health. Our findings provide evidence of the impact of symptoms of persistent lymphedema on the quality of survivorship of older women. 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Follow‐up</title></titleStmt><publicationStmt><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><availability><licence>© 2009 Wiley Periodicals, Inc.</licence></availability><date type="published" when="2010-03"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Older Breast Cancer Survivors: Factors Associated with Self‐reported Symptoms of Persistent Lymphedema Over 7 years of Follow‐up</title><title level="a" type="short">Older Breast Cancer Survivors Symptoms of Lymphedema</title><author xml:id="author-0000"><persName><forename type="first">Kerri M.</forename><surname>Clough‐Gorr</surname><roleName type="degree">DSc, MPH</roleName></persName><affiliation>Geriatrics Section, Boston University Schools of Medicine and Public Health, Boston, Massachusetts<address><country key="US"></country></address></affiliation><affiliation>Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland<address><country key="CH"></country></address></affiliation><affiliation>Department of Geriatrics, Inselspital University of Bern Hospital, Bern, Switzerland<address><country key="CH"></country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">Patricia A.</forename><surname>Ganz</surname><roleName type="degree">MD</roleName></persName><affiliation>University of California at Los Angeles Schools of Medicine and Public Health, Los Angeles, California<address><country key="US"></country></address></affiliation><affiliation>Jonsson Comprehensive Cancer Center at UCLA, Los Angeles, California<address><country key="US"></country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">Rebecca A.</forename><surname>Silliman</surname><roleName type="degree">MD, PhD</roleName></persName><affiliation>Geriatrics Section, Boston University Schools of Medicine and Public Health, Boston, Massachusetts<address><country key="US"></country></address></affiliation></author><idno type="istex">F0DFAD1FAC4C36D539968EDC5A91ED247D145B16</idno><idno type="DOI">10.1111/j.1524-4741.2009.00878.x</idno><idno type="unit">TBJ878</idno><idno type="toTypesetVersion">file:TBJ.TBJ878.pdf</idno></analytic><monogr><title level="j" type="main">The Breast Journal</title><title level="j" type="alt">BREAST JOURNAL</title><idno type="pISSN">1075-122X</idno><idno type="eISSN">1524-4741</idno><idno type="book-DOI">10.1111/(ISSN)1524-4741</idno><idno type="book-part-DOI">10.1111/tbj.2010.16.issue-2</idno><idno type="product">TBJ</idno><idno type="publisherDivision">ST</idno><imprint><biblScope unit="vol">16</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="147">147</biblScope><biblScope unit="page" to="155">155</biblScope><biblScope unit="page-count">9</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2010-03"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><p><hi rend="bold">Abstract: </hi> Lymphedema of the arm is a common complication of breast cancer with symptoms that can persist over long periods of time. For older women (over 50% of breast cancer cases) it means living with the potential for long‐term complications of persistent lymphedema in conjunction with the common diseases and disabilities of aging over survivorship. We identified women ≥65 years diagnosed with primary stage I–IIIA breast cancer. Data were collected over 7 years of follow‐up from consenting patients’ medical records and telephone interviews. Data collected included self‐reported symptoms of persistent lymphedema, breast cancer characteristics, and selected sociodemographic and health‐related characteristics. The overall prevalence of symptoms of persistent lymphedema was 36% over 7 years of follow‐up. Having stage II or III (OR = 1.77, 95% CI: 1.07–2.93) breast cancer and having a BMI >30 (OR = 3.04, 95% CI: 1.69–5.45) were statistically significantly predictive of symptoms of persistent lymphedema. Women ≥80 years were less likely to report symptoms of persistent lymphedema when compared to younger women (OR = 0.44, 95% CI: 0.18–0.95). Women with symptoms of persistent lymphedema consistently reported worse general mental health and physical function. Symptoms of persistent lymphedema were common in this population of older breast cancer survivors and had a noticeable effect on both physical function and general mental health. Our findings provide evidence of the impact of symptoms of persistent lymphedema on the quality of survivorship of older women<hi rend="italic">.</hi> Clinical and research efforts focused on risk factors for symptoms of persistent lymphedema in older breast cancer survivors may lead to preventative and therapeutic measures that help maintain their health and well‐being over increasing periods of survivorship.</p></abstract><textClass><keywords xml:lang="en"><term xml:id="k1">breast cancer</term><term xml:id="k2">lymphedema</term><term xml:id="k3">older women</term><term xml:id="k4">persistent lymphedema</term><term xml:id="k5">survivor</term><term xml:id="k6">symptoms</term></keywords><classCode scheme="tocHeading1">ORIGINAL ARTICLES</classCode></textClass><langUsage><language ident="EN"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/F0DFAD1FAC4C36D539968EDC5A91ED247D145B16/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1524-4741</doi><issn type="print">1075-122X</issn><issn type="electronic">1524-4741</issn><idGroup><id type="product" value="TBJ"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="BREAST JOURNAL">The Breast Journal</title></titleGroup></publicationMeta><publicationMeta level="part" position="03002"><doi origin="wiley">10.1111/tbj.2010.16.issue-2</doi><numberingGroup><numbering type="journalVolume" number="16">16</numbering><numbering type="journalIssue" number="2">2</numbering></numberingGroup><coverDate startDate="2010-03">March/April 2010</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="6" status="forIssue"><doi origin="wiley">10.1111/j.1524-4741.2009.00878.x</doi><idGroup><id type="unit" value="TBJ878"></id></idGroup><countGroup><count type="pageTotal" number="9"></count></countGroup><titleGroup><title type="tocHeading1">ORIGINAL ARTICLES</title></titleGroup><copyright>© 2009 Wiley Periodicals, Inc.</copyright><eventGroup><event type="firstOnline" date="2009-11-24"></event><event type="publishedOnlineFinalForm" date="2010-03-12"></event><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.2 mode:FullText source:FullText result:FullText" date="2010-03-16"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-10"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-11-04"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="147">147</numbering><numbering type="pageLast" number="155">155</numbering></numberingGroup><correspondenceTo>Address correspondence and reprint requests to: Kerri M. Clough‐Gorr, DSc, MPH, Boston University Medical Center, 88 East Newton Street, Robinson 2, Boston, MA 02118, USA, or e‐mail: <email>kmclough@bu.edu</email></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:TBJ.TBJ878.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="3"></count><count type="tableTotal" number="3"></count></countGroup><titleGroup><title type="main">Older Breast Cancer Survivors: Factors Associated with Self‐reported Symptoms of Persistent Lymphedema Over 7 years of Follow‐up</title><title type="shortAuthors">CLOUGH‐GORR ET AL.</title><title type="short"><i>Older Breast Cancer Survivors Symptoms of Lymphedema</i></title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1 #a2 #a3"><personName><givenNames>Kerri M.</givenNames><familyName>Clough‐Gorr</familyName><degrees>DSc, MPH</degrees></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a4 #a5"><personName><givenNames>Patricia A.</givenNames><familyName>Ganz</familyName><degrees>MD</degrees></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#a1"><personName><givenNames>Rebecca A.</givenNames><familyName>Silliman</familyName><degrees>MD, PhD</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="a1" countryCode="US"><unparsedAffiliation>Geriatrics Section, Boston University Schools of Medicine and Public Health, Boston, Massachusetts</unparsedAffiliation></affiliation><affiliation xml:id="a2" countryCode="CH"><unparsedAffiliation>Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland</unparsedAffiliation></affiliation><affiliation xml:id="a3" countryCode="CH"><unparsedAffiliation>Department of Geriatrics, Inselspital University of Bern Hospital, Bern, Switzerland</unparsedAffiliation></affiliation><affiliation xml:id="a4" countryCode="US"><unparsedAffiliation>University of California at Los Angeles Schools of Medicine and Public Health, Los Angeles, California</unparsedAffiliation></affiliation><affiliation xml:id="a5" countryCode="US"><unparsedAffiliation>Jonsson Comprehensive Cancer Center at UCLA, Los Angeles, California</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1">breast cancer</keyword><keyword xml:id="k2">lymphedema</keyword><keyword xml:id="k3">older women</keyword><keyword xml:id="k4">persistent lymphedema</keyword><keyword xml:id="k5">survivor</keyword><keyword xml:id="k6">symptoms</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><p><b>Abstract: </b> Lymphedema of the arm is a common complication of breast cancer with symptoms that can persist over long periods of time. For older women (over 50% of breast cancer cases) it means living with the potential for long‐term complications of persistent lymphedema in conjunction with the common diseases and disabilities of aging over survivorship. We identified women ≥65 years diagnosed with primary stage I–IIIA breast cancer. Data were collected over 7 years of follow‐up from consenting patients’ medical records and telephone interviews. Data collected included self‐reported symptoms of persistent lymphedema, breast cancer characteristics, and selected sociodemographic and health‐related characteristics. The overall prevalence of symptoms of persistent lymphedema was 36% over 7 years of follow‐up. Having stage II or III (OR = 1.77, 95% CI: 1.07–2.93) breast cancer and having a BMI >30 (OR = 3.04, 95% CI: 1.69–5.45) were statistically significantly predictive of symptoms of persistent lymphedema. Women ≥80 years were less likely to report symptoms of persistent lymphedema when compared to younger women (OR = 0.44, 95% CI: 0.18–0.95). Women with symptoms of persistent lymphedema consistently reported worse general mental health and physical function. Symptoms of persistent lymphedema were common in this population of older breast cancer survivors and had a noticeable effect on both physical function and general mental health. Our findings provide evidence of the impact of symptoms of persistent lymphedema on the quality of survivorship of older women<i>.</i> Clinical and research efforts focused on risk factors for symptoms of persistent lymphedema in older breast cancer survivors may lead to preventative and therapeutic measures that help maintain their health and well‐being over increasing periods of survivorship.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Older Breast Cancer Survivors: Factors Associated with Self‐reported Symptoms of Persistent Lymphedema Over 7 years of Follow‐up</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Older Breast Cancer Survivors Symptoms of Lymphedema</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Older Breast Cancer Survivors: Factors Associated with Self‐reported Symptoms of Persistent Lymphedema Over 7 years of Follow‐up</title></titleInfo><name type="personal"><namePart type="given">Kerri M.</namePart><namePart type="family">Clough‐Gorr</namePart><namePart type="termsOfAddress">DSc, MPH</namePart><affiliation>Geriatrics Section, Boston University Schools of Medicine and Public Health, Boston, Massachusetts</affiliation><affiliation>Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland</affiliation><affiliation>Department of Geriatrics, Inselspital University of Bern Hospital, Bern, Switzerland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Patricia A.</namePart><namePart type="family">Ganz</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>University of California at Los Angeles Schools of Medicine and Public Health, Los Angeles, California</affiliation><affiliation>Jonsson Comprehensive Cancer Center at UCLA, Los Angeles, California</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Rebecca A.</namePart><namePart type="family">Silliman</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>Geriatrics Section, Boston University Schools of Medicine and Public Health, Boston, Massachusetts</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2010-03</dateIssued><copyrightDate encoding="w3cdtf">2010</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">3</extent><extent unit="tables">3</extent></physicalDescription><abstract>Abstract: Lymphedema of the arm is a common complication of breast cancer with symptoms that can persist over long periods of time. For older women (over 50% of breast cancer cases) it means living with the potential for long‐term complications of persistent lymphedema in conjunction with the common diseases and disabilities of aging over survivorship. We identified women ≥65 years diagnosed with primary stage I–IIIA breast cancer. Data were collected over 7 years of follow‐up from consenting patients’ medical records and telephone interviews. Data collected included self‐reported symptoms of persistent lymphedema, breast cancer characteristics, and selected sociodemographic and health‐related characteristics. The overall prevalence of symptoms of persistent lymphedema was 36% over 7 years of follow‐up. Having stage II or III (OR = 1.77, 95% CI: 1.07–2.93) breast cancer and having a BMI >30 (OR = 3.04, 95% CI: 1.69–5.45) were statistically significantly predictive of symptoms of persistent lymphedema. Women ≥80 years were less likely to report symptoms of persistent lymphedema when compared to younger women (OR = 0.44, 95% CI: 0.18–0.95). Women with symptoms of persistent lymphedema consistently reported worse general mental health and physical function. Symptoms of persistent lymphedema were common in this population of older breast cancer survivors and had a noticeable effect on both physical function and general mental health. Our findings provide evidence of the impact of symptoms of persistent lymphedema on the quality of survivorship of older women. Clinical and research efforts focused on risk factors for symptoms of persistent lymphedema in older breast cancer survivors may lead to preventative and therapeutic measures that help maintain their health and well‐being over increasing periods of survivorship.</abstract><subject lang="en"><genre>keywords</genre><topic>breast cancer</topic><topic>lymphedema</topic><topic>older women</topic><topic>persistent lymphedema</topic><topic>survivor</topic><topic>symptoms</topic></subject><relatedItem type="host"><titleInfo><title>The Breast Journal</title></titleInfo><genre type="journal">journal</genre><identifier type="ISSN">1075-122X</identifier><identifier type="eISSN">1524-4741</identifier><identifier type="DOI">10.1111/(ISSN)1524-4741</identifier><identifier type="PublisherID">TBJ</identifier><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>16</number></detail><detail type="issue"><caption>no.</caption><number>2</number></detail><extent unit="pages"><start>147</start><end>155</end><total>9</total></extent></part></relatedItem><identifier type="istex">F0DFAD1FAC4C36D539968EDC5A91ED247D145B16</identifier><identifier type="DOI">10.1111/j.1524-4741.2009.00878.x</identifier><identifier type="ArticleID">TBJ878</identifier><accessCondition type="use and reproduction" contentType="copyright">© 2009 Wiley Periodicals, Inc.</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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