Intradermal radioisotope injection is superior to subdermal injection for the identification of the sentinel node in breast cancer patients
Identifieur interne : 006E45 ( Istex/Corpus ); précédent : 006E44; suivant : 006E46Intradermal radioisotope injection is superior to subdermal injection for the identification of the sentinel node in breast cancer patients
Auteurs : Kazuyoshi Motomura ; Yoshifumi Komoike ; Yoshihisa Hasegawa ; Tsutomu Kasugai ; Hideo Inaji ; Shinzaburo Noguchi ; Hiroki KoyamaSource :
- Journal of Surgical Oncology [ 0022-4790 ] ; 2003-02.
Abstract
The purpose of the present study was to evaluate whether the intradermal injection of radiocolloids would improve the identification rate of sentinel nodes over the subdermal injection in breast cancer patients.
Url:
DOI: 10.1002/jso.10200
Links to Exploration step
ISTEX:EB9D0C202042CE3E9EA657C2CB741B52BB5A0674Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Intradermal radioisotope injection is superior to subdermal injection for the identification of the sentinel node in breast cancer patients</title><author><name sortKey="Motomura, Kazuyoshi" sort="Motomura, Kazuyoshi" uniqKey="Motomura K" first="Kazuyoshi" last="Motomura">Kazuyoshi Motomura</name><affiliation><mods:affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, 1‐3‐3 Nakamichi, Higashinari‐ku, Osaka 537‐8511, Japan. Fax: +81‐6‐6981‐8055</mods:affiliation></affiliation></author><author><name sortKey="Komoike, Yoshifumi" sort="Komoike, Yoshifumi" uniqKey="Komoike Y" first="Yoshifumi" last="Komoike">Yoshifumi Komoike</name><affiliation><mods:affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</mods:affiliation></affiliation></author><author><name sortKey="Hasegawa, Yoshihisa" sort="Hasegawa, Yoshihisa" uniqKey="Hasegawa Y" first="Yoshihisa" last="Hasegawa">Yoshihisa Hasegawa</name><affiliation><mods:affiliation>Department of Nuclear Medicine, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</mods:affiliation></affiliation></author><author><name sortKey="Kasugai, Tsutomu" sort="Kasugai, Tsutomu" uniqKey="Kasugai T" first="Tsutomu" last="Kasugai">Tsutomu Kasugai</name><affiliation><mods:affiliation>Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</mods:affiliation></affiliation></author><author><name sortKey="Inaji, Hideo" sort="Inaji, Hideo" uniqKey="Inaji H" first="Hideo" last="Inaji">Hideo Inaji</name><affiliation><mods:affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</mods:affiliation></affiliation></author><author><name sortKey="Noguchi, Shinzaburo" sort="Noguchi, Shinzaburo" uniqKey="Noguchi S" first="Shinzaburo" last="Noguchi">Shinzaburo Noguchi</name><affiliation><mods:affiliation>Department of Surgical Oncology, Osaka University Medical School, Osaka, Japan</mods:affiliation></affiliation></author><author><name sortKey="Koyama, Hiroki" sort="Koyama, Hiroki" uniqKey="Koyama H" first="Hiroki" last="Koyama">Hiroki Koyama</name><affiliation><mods:affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:EB9D0C202042CE3E9EA657C2CB741B52BB5A0674</idno><date when="2003" year="2003">2003</date><idno type="doi">10.1002/jso.10200</idno><idno type="url">https://api.istex.fr/document/EB9D0C202042CE3E9EA657C2CB741B52BB5A0674/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">006E45</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">006E45</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Intradermal radioisotope injection is superior to subdermal injection for the identification of the sentinel node in breast cancer patients</title><author><name sortKey="Motomura, Kazuyoshi" sort="Motomura, Kazuyoshi" uniqKey="Motomura K" first="Kazuyoshi" last="Motomura">Kazuyoshi Motomura</name><affiliation><mods:affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, 1‐3‐3 Nakamichi, Higashinari‐ku, Osaka 537‐8511, Japan. Fax: +81‐6‐6981‐8055</mods:affiliation></affiliation></author><author><name sortKey="Komoike, Yoshifumi" sort="Komoike, Yoshifumi" uniqKey="Komoike Y" first="Yoshifumi" last="Komoike">Yoshifumi Komoike</name><affiliation><mods:affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</mods:affiliation></affiliation></author><author><name sortKey="Hasegawa, Yoshihisa" sort="Hasegawa, Yoshihisa" uniqKey="Hasegawa Y" first="Yoshihisa" last="Hasegawa">Yoshihisa Hasegawa</name><affiliation><mods:affiliation>Department of Nuclear Medicine, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</mods:affiliation></affiliation></author><author><name sortKey="Kasugai, Tsutomu" sort="Kasugai, Tsutomu" uniqKey="Kasugai T" first="Tsutomu" last="Kasugai">Tsutomu Kasugai</name><affiliation><mods:affiliation>Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</mods:affiliation></affiliation></author><author><name sortKey="Inaji, Hideo" sort="Inaji, Hideo" uniqKey="Inaji H" first="Hideo" last="Inaji">Hideo Inaji</name><affiliation><mods:affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</mods:affiliation></affiliation></author><author><name sortKey="Noguchi, Shinzaburo" sort="Noguchi, Shinzaburo" uniqKey="Noguchi S" first="Shinzaburo" last="Noguchi">Shinzaburo Noguchi</name><affiliation><mods:affiliation>Department of Surgical Oncology, Osaka University Medical School, Osaka, Japan</mods:affiliation></affiliation></author><author><name sortKey="Koyama, Hiroki" sort="Koyama, Hiroki" uniqKey="Koyama H" first="Hiroki" last="Koyama">Hiroki Koyama</name><affiliation><mods:affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Surgical Oncology</title><title level="j" type="alt">JOURNAL OF SURGICAL ONCOLOGY</title><idno type="ISSN">0022-4790</idno><idno type="eISSN">1096-9098</idno><imprint><biblScope unit="vol">82</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="91">91</biblScope><biblScope unit="page" to="97">97</biblScope><biblScope unit="page-count">7</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>New York</pubPlace><date type="published" when="2003-02">2003-02</date></imprint><idno type="ISSN">0022-4790</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0022-4790</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">The purpose of the present study was to evaluate whether the intradermal injection of radiocolloids would improve the identification rate of sentinel nodes over the subdermal injection in breast cancer patients.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>node</json:string><json:string>intradermal</json:string><json:string>subdermal</json:string><json:string>radioisotope</json:string><json:string>sentinel node biopsy</json:string><json:string>colloid</json:string><json:string>intradermal injection</json:string><json:string>sentinel node</json:string><json:string>axillary</json:string><json:string>sentinel</json:string><json:string>breast cancer</json:string><json:string>subdermal injection</json:string><json:string>surg</json:string><json:string>intradermal injection group</json:string><json:string>sentinel nodes</json:string><json:string>lymphoscintigraphy</json:string><json:string>peritumoral</json:string><json:string>radiocolloids</json:string><json:string>subdermal injection group</json:string><json:string>oncol</json:string><json:string>injection</json:string><json:string>lymphatic</json:string><json:string>biopsy</json:string><json:string>breast cancer patients</json:string><json:string>lymphatic mapping</json:string><json:string>surg oncol</json:string><json:string>gamma probe</json:string><json:string>motomura</json:string><json:string>success rate</json:string><json:string>peritumoral injection</json:string><json:string>intradermal radioisotope injection</json:string><json:string>colloidal albumin</json:string><json:string>large particle size</json:string><json:string>cardiovascular diseases</json:string><json:string>lymph</json:string><json:string>intraparenchymal injection</json:string><json:string>sulfur colloids</json:string><json:string>surgical</json:string><json:string>sulfur</json:string></teeft></keywords><author><json:item><name>Kazuyoshi Motomura MD</name><affiliations><json:string>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</json:string><json:string>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, 1‐3‐3 Nakamichi, Higashinari‐ku, Osaka 537‐8511, Japan. Fax: +81‐6‐6981‐8055</json:string></affiliations></json:item><json:item><name>Yoshifumi Komoike MD</name><affiliations><json:string>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</json:string></affiliations></json:item><json:item><name>Yoshihisa Hasegawa MD</name><affiliations><json:string>Department of Nuclear Medicine, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</json:string></affiliations></json:item><json:item><name>Tsutomu Kasugai MD</name><affiliations><json:string>Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</json:string></affiliations></json:item><json:item><name>Hideo Inaji MD</name><affiliations><json:string>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</json:string></affiliations></json:item><json:item><name>Shinzaburo Noguchi MD</name><affiliations><json:string>Department of Surgical Oncology, Osaka University Medical School, Osaka, Japan</json:string></affiliations></json:item><json:item><name>Hiroki Koyama MD</name><affiliations><json:string>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>sentinel node</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>breast cancer</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>sentinel node biopsy</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>intradermal injection</value></json:item></subject><articleId><json:string>JSO10200</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><qualityIndicators><score>4.349</score><pdfVersion>1.3</pdfVersion><pdfPageSize>594 x 792 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>211</abstractCharCount><pdfWordCount>3977</pdfWordCount><pdfCharCount>25887</pdfCharCount><pdfPageCount>6</pdfPageCount><abstractWordCount>31</abstractWordCount></qualityIndicators><title>Intradermal radioisotope injection is superior to subdermal injection for the identification of the sentinel node in breast cancer patients</title><genre><json:string>article</json:string></genre><host><title>Journal of Surgical Oncology</title><language><json:string>unknown</json:string></language><doi><json:string>10.1002/(ISSN)1096-9098</json:string></doi><issn><json:string>0022-4790</json:string></issn><eissn><json:string>1096-9098</json:string></eissn><publisherId><json:string>JSO</json:string></publisherId><volume>82</volume><issue>2</issue><pages><first>91</first><last>97</last><total>7</total></pages><genre><json:string>journal</json:string></genre><subject><json:item><value>Research Article</value></json:item></subject></host><categories><wos><json:string>science</json:string><json:string>surgery</json:string><json:string>oncology</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>clinical medicine</json:string><json:string>oncology & carcinogenesis</json:string></scienceMetrix></categories><publicationDate>2003</publicationDate><copyrightDate>2003</copyrightDate><doi><json:string>10.1002/jso.10200</json:string></doi><id>EB9D0C202042CE3E9EA657C2CB741B52BB5A0674</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/EB9D0C202042CE3E9EA657C2CB741B52BB5A0674/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/EB9D0C202042CE3E9EA657C2CB741B52BB5A0674/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/EB9D0C202042CE3E9EA657C2CB741B52BB5A0674/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Intradermal radioisotope injection is superior to subdermal injection for the identification of the sentinel node in breast cancer patients</title></titleStmt><publicationStmt><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>New York</pubPlace><availability><licence>Copyright © 2003 Wiley‐Liss, Inc.</licence></availability><date type="published" when="2003-02"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main" xml:lang="en">Intradermal radioisotope injection is superior to subdermal injection for the identification of the sentinel node in breast cancer patients</title><title level="a" type="short" xml:lang="en">Sentinel Node Biopsy Using Intradermal Radioisotope Injection</title><author xml:id="author-0000" role="corresp"><persName><forename type="first">Kazuyoshi</forename><surname>Motomura</surname><roleName type="degree">MD</roleName></persName><email>motomurak@hotmail.com</email><affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan<address><country key="JP"></country></address></affiliation><affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, 1‐3‐3 Nakamichi, Higashinari‐ku, Osaka 537‐8511, Japan. Fax: +81‐6‐6981‐8055</affiliation></author><author xml:id="author-0001"><persName><forename type="first">Yoshifumi</forename><surname>Komoike</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan<address><country key="JP"></country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">Yoshihisa</forename><surname>Hasegawa</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Nuclear Medicine, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan<address><country key="JP"></country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">Tsutomu</forename><surname>Kasugai</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan<address><country key="JP"></country></address></affiliation></author><author xml:id="author-0004"><persName><forename type="first">Hideo</forename><surname>Inaji</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan<address><country key="JP"></country></address></affiliation></author><author xml:id="author-0005"><persName><forename type="first">Shinzaburo</forename><surname>Noguchi</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Surgical Oncology, Osaka University Medical School, Osaka, Japan<address><country key="JP"></country></address></affiliation></author><author xml:id="author-0006"><persName><forename type="first">Hiroki</forename><surname>Koyama</surname><roleName type="degree">MD</roleName></persName><affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan<address><country key="JP"></country></address></affiliation></author><idno type="istex">EB9D0C202042CE3E9EA657C2CB741B52BB5A0674</idno><idno type="DOI">10.1002/jso.10200</idno><idno type="unit">JSO10200</idno><idno type="toTypesetVersion">file:JSO.JSO10200.pdf</idno></analytic><monogr><title level="j" type="main">Journal of Surgical Oncology</title><title level="j" type="alt">JOURNAL OF SURGICAL ONCOLOGY</title><idno type="pISSN">0022-4790</idno><idno type="eISSN">1096-9098</idno><idno type="book-DOI">10.1002/(ISSN)1096-9098</idno><idno type="book-part-DOI">10.1002/jso.v82:2</idno><idno type="product">JSO</idno><imprint><biblScope unit="vol">82</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="91">91</biblScope><biblScope unit="page" to="97">97</biblScope><biblScope unit="page-count">7</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>New York</pubPlace><date type="published" when="2003-02"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><head>Abstract</head>
Background and Objectives
<p>The purpose of the present study was to evaluate whether the intradermal injection of radiocolloids would improve the identification rate of sentinel nodes over the subdermal injection in breast cancer patients.</p>
Methods
<p>Sentinel node biopsy was performed in T2 breast cancer patients with clinically negative nodes, using subdermal or intradermal injection of radioisotopes with the peritumoral dye injection. We used Tc‐99m tin colloid, with a larger particle size (0.4–5 μm), rather than sulfur colloid and colloidal albumin.</p>
Results
<p>The initial 55 patients underwent subdermal injection of radiocolloids; the next 61 patients underwent intradermal injection of radiocolloids for sentinel node biopsy. The detection rate of sentinel nodes was significantly (<hi rend="italic">P</hi> = 0.048) higher in the intradermal injection group (61/61, 100%) than in the subdermal injection group (51/55, 92.7%). False‐negative rates were comparable between the two groups. Lymphoscintigraphy visualized the sentinel nodes significantly (<hi rend="italic">P</hi> < 0.0001) more often in the intradermal injection group (59/61, 96.7%) than in the subdermal injection group (20/54, 37.0%).</p>
Conclusions
<p>A significantly higher identification rate of sentinel node biopsy and lymphoscintigraphy can be achieved by intradermal injection of Tc‐99m tin colloid with a large particle size than by subdermal injection. J. Surg. Oncol. 2003;82:91–97. © 2003 Wiley‐Liss, Inc.</p></abstract><textClass><keywords xml:lang="en"><term xml:id="kwd1">sentinel node</term><term xml:id="kwd2">breast cancer</term><term xml:id="kwd3">sentinel node biopsy</term><term xml:id="kwd4">intradermal injection</term></keywords><classCode scheme="articleCategory">Research Article</classCode><classCode scheme="tocHeading1">Research Articles</classCode></textClass><langUsage><language ident="EN"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/EB9D0C202042CE3E9EA657C2CB741B52BB5A0674/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>New York</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1096-9098</doi><issn type="print">0022-4790</issn><issn type="electronic">1096-9098</issn><idGroup><id type="product" value="JSO"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="JOURNAL OF SURGICAL ONCOLOGY">Journal of Surgical Oncology</title><title type="short">J. Surg. Oncol.</title></titleGroup></publicationMeta><publicationMeta level="part" position="20"><doi origin="wiley" registered="yes">10.1002/jso.v82:2</doi><numberingGroup><numbering type="journalVolume" number="82">82</numbering><numbering type="journalIssue">2</numbering></numberingGroup><coverDate startDate="2003-02">February 2003</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="3" status="forIssue"><doi origin="wiley" registered="yes">10.1002/jso.10200</doi><idGroup><id type="unit" value="JSO10200"></id></idGroup><countGroup><count type="pageTotal" number="7"></count></countGroup><titleGroup><title type="articleCategory">Research Article</title><title type="tocHeading1">Research Articles</title></titleGroup><copyright ownership="publisher">Copyright © 2003 Wiley‐Liss, Inc.</copyright><eventGroup><event type="manuscriptAccepted" date="2002-11-01"></event><event type="firstOnline" date="2003-01-29"></event><event type="publishedOnlineFinalForm" date="2003-01-29"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.3.2 mode:FullText source:HeaderRef result:HeaderRef" date="2010-03-10"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-01"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-30"></event></eventGroup><numberingGroup><numbering type="pageFirst">91</numbering><numbering type="pageLast">97</numbering></numberingGroup><correspondenceTo>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, 1‐3‐3 Nakamichi, Higashinari‐ku, Osaka 537‐8511, Japan. Fax: +81‐6‐6981‐8055</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:JSO.JSO10200.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="0"></count><count type="tableTotal" number="4"></count><count type="referenceTotal" number="29"></count><count type="wordTotal" number="932"></count></countGroup><titleGroup><title type="main" xml:lang="en">Intradermal radioisotope injection is superior to subdermal injection for the identification of the sentinel node in breast cancer patients</title><title type="short" xml:lang="en">Sentinel Node Biopsy Using Intradermal Radioisotope Injection</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Kazuyoshi</givenNames><familyName>Motomura</familyName><degrees>MD</degrees></personName><contactDetails><email>motomurak@hotmail.com</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Yoshifumi</givenNames><familyName>Komoike</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Yoshihisa</givenNames><familyName>Hasegawa</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af3"><personName><givenNames>Tsutomu</givenNames><familyName>Kasugai</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Hideo</givenNames><familyName>Inaji</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au6" creatorRole="author" affiliationRef="#af4"><personName><givenNames>Shinzaburo</givenNames><familyName>Noguchi</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au7" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Hiroki</givenNames><familyName>Koyama</familyName><degrees>MD</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="JP" type="organization"><unparsedAffiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="JP" type="organization"><unparsedAffiliation>Department of Nuclear Medicine, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="JP" type="organization"><unparsedAffiliation>Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</unparsedAffiliation></affiliation><affiliation xml:id="af4" countryCode="JP" type="organization"><unparsedAffiliation>Department of Surgical Oncology, Osaka University Medical School, Osaka, Japan</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">sentinel node</keyword><keyword xml:id="kwd2">breast cancer</keyword><keyword xml:id="kwd3">sentinel node biopsy</keyword><keyword xml:id="kwd4">intradermal injection</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><section xml:id="abs1-1"><title type="main">Background and Objectives</title><p>The purpose of the present study was to evaluate whether the intradermal injection of radiocolloids would improve the identification rate of sentinel nodes over the subdermal injection in breast cancer patients.</p></section><section xml:id="abs1-2"><title type="main">Methods</title><p>Sentinel node biopsy was performed in T2 breast cancer patients with clinically negative nodes, using subdermal or intradermal injection of radioisotopes with the peritumoral dye injection. We used Tc‐99m tin colloid, with a larger particle size (0.4–5 μm), rather than sulfur colloid and colloidal albumin.</p></section><section xml:id="abs1-3"><title type="main">Results</title><p>The initial 55 patients underwent subdermal injection of radiocolloids; the next 61 patients underwent intradermal injection of radiocolloids for sentinel node biopsy. The detection rate of sentinel nodes was significantly (<i>P</i> = 0.048) higher in the intradermal injection group (61/61, 100%) than in the subdermal injection group (51/55, 92.7%). False‐negative rates were comparable between the two groups. Lymphoscintigraphy visualized the sentinel nodes significantly (<i>P</i> < 0.0001) more often in the intradermal injection group (59/61, 96.7%) than in the subdermal injection group (20/54, 37.0%).</p></section><section xml:id="abs1-4"><title type="main">Conclusions</title><p>A significantly higher identification rate of sentinel node biopsy and lymphoscintigraphy can be achieved by intradermal injection of Tc‐99m tin colloid with a large particle size than by subdermal injection. J. Surg. Oncol. 2003;82:91–97. © 2003 Wiley‐Liss, Inc.</p></section></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Intradermal radioisotope injection is superior to subdermal injection for the identification of the sentinel node in breast cancer patients</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Sentinel Node Biopsy Using Intradermal Radioisotope Injection</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Intradermal radioisotope injection is superior to subdermal injection for the identification of the sentinel node in breast cancer patients</title></titleInfo><name type="personal"><namePart type="given">Kazuyoshi</namePart><namePart type="family">Motomura</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</affiliation><affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, 1‐3‐3 Nakamichi, Higashinari‐ku, Osaka 537‐8511, Japan. Fax: +81‐6‐6981‐8055</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yoshifumi</namePart><namePart type="family">Komoike</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yoshihisa</namePart><namePart type="family">Hasegawa</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Nuclear Medicine, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Tsutomu</namePart><namePart type="family">Kasugai</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hideo</namePart><namePart type="family">Inaji</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Shinzaburo</namePart><namePart type="family">Noguchi</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Surgical Oncology, Osaka University Medical School, Osaka, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hiroki</namePart><namePart type="family">Koyama</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">New York</placeTerm></place><dateIssued encoding="w3cdtf">2003-02</dateIssued><dateValid encoding="w3cdtf">2002-11-01</dateValid><copyrightDate encoding="w3cdtf">2003</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="tables">4</extent><extent unit="references">29</extent><extent unit="words">932</extent></physicalDescription><abstract>The purpose of the present study was to evaluate whether the intradermal injection of radiocolloids would improve the identification rate of sentinel nodes over the subdermal injection in breast cancer patients.</abstract><abstract>Sentinel node biopsy was performed in T2 breast cancer patients with clinically negative nodes, using subdermal or intradermal injection of radioisotopes with the peritumoral dye injection. We used Tc‐99m tin colloid, with a larger particle size (0.4–5 μm), rather than sulfur colloid and colloidal albumin.</abstract><abstract>The initial 55 patients underwent subdermal injection of radiocolloids; the next 61 patients underwent intradermal injection of radiocolloids for sentinel node biopsy. The detection rate of sentinel nodes was significantly (P = 0.048) higher in the intradermal injection group (61/61, 100%) than in the subdermal injection group (51/55, 92.7%). False‐negative rates were comparable between the two groups. Lymphoscintigraphy visualized the sentinel nodes significantly (P < 0.0001) more often in the intradermal injection group (59/61, 96.7%) than in the subdermal injection group (20/54, 37.0%).</abstract><abstract>A significantly higher identification rate of sentinel node biopsy and lymphoscintigraphy can be achieved by intradermal injection of Tc‐99m tin colloid with a large particle size than by subdermal injection. J. Surg. Oncol. 2003;82:91–97. © 2003 Wiley‐Liss, Inc.</abstract><subject lang="en"><genre>keywords</genre><topic>sentinel node</topic><topic>breast cancer</topic><topic>sentinel node biopsy</topic><topic>intradermal injection</topic></subject><relatedItem type="host"><titleInfo><title>Journal of Surgical Oncology</title></titleInfo><titleInfo type="abbreviated"><title>J. Surg. Oncol.</title></titleInfo><genre type="journal">journal</genre><subject><genre>article-category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0022-4790</identifier><identifier type="eISSN">1096-9098</identifier><identifier type="DOI">10.1002/(ISSN)1096-9098</identifier><identifier type="PublisherID">JSO</identifier><part><date>2003</date><detail type="volume"><caption>vol.</caption><number>82</number></detail><detail type="issue"><caption>no.</caption><number>2</number></detail><extent unit="pages"><start>91</start><end>97</end><total>7</total></extent></part></relatedItem><identifier type="istex">EB9D0C202042CE3E9EA657C2CB741B52BB5A0674</identifier><identifier type="DOI">10.1002/jso.10200</identifier><identifier type="ArticleID">JSO10200</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2003 Wiley‐Liss, Inc.</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 006E45 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 006E45 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:EB9D0C202042CE3E9EA657C2CB741B52BB5A0674
|texte= Intradermal radioisotope injection is superior to subdermal injection for the identification of the sentinel node in breast cancer patients
}}
| This area was generated with Dilib version V0.6.31. |  |